The Charles Institute of Dermatology has several active research projects, spread across 5 different groups and categorized into 8 different thematic areas, which you can view below.
Inflammatory Skin Diseases Projects
![Breast Cancer Ireland](/charles/t4media/microscope-275984 200w200h.jpg)
Elucidation of the survival characteristics of immature melanocytes in the depigmenting skin disorders vitiligo
![Breast Cancer Ireland](/charles/t4media/microscope-275984 200w200h.jpg)
Systemic and pilo-sebaceous inflammation in hidradenitis suppurativa
![Breast Cancer Ireland](/charles/t4media/microscope-275984 200w200h.jpg)
Wound Healing and Wound Care Projects
![Breast Cancer Ireland](/charles/t4media/microscope-275984 200w200h.jpg)
Chronic wound repair via cell-free delivery of tailored ADSC-derived exosomes using an injectable hydrogel through polarizing M2 macrophages
![Breast Cancer Ireland](/charles/t4media/microscope-275984 200w200h.jpg)
Diabetic Wound Healing through an Injectable and Tuneable Extracellular Matrix Derived Hydrogel as a Stem Cell Delivery Niche
![Breast Cancer Ireland](/charles/t4media/microscope-275984 200w200h.jpg)
Mechanism study of the Cu(0)-mediated RDRP; Controlled polymerization of multivinyl monomers
![Breast Cancer Ireland](/charles/t4media/microscope-275984 200w200h.jpg)
Hyperbranched Poly(beta-amino ester)s based functionalised hydrogel scaffolds for wound healing
![Breast Cancer Ireland](/charles/t4media/microscope-275984 200w200h.jpg)
Design and development of an injectable hydrogel loaded with exosomes derived of AD-SCs for treatment of chronic skin wounds
![Breast Cancer Ireland](/charles/t4media/microscope-275984 200w200h.jpg)
Injectable hydrogel combining exosomes for chronic wound repair
![Breast Cancer Ireland](/charles/t4media/microscope-275984 200w200h.jpg)
Design and development of ECM-based material for wound healing applications
Rare Skin Diseases Projects
![Breast Cancer Ireland](/charles/t4media/microscope-275984 200w200h.jpg)
A Disruptive Gene Therapy Platform, Replacing viruses in the Treatment of Genetic Conditions (DTIF)
![Breast Cancer Ireland](/charles/t4media/microscope-275984 200w200h.jpg)
Multifunctional single-chain cyclized/knot polymers and their applications for Recessive Dystrophic Epidermolysis Bullosa (RDEB) wound healing
![Breast Cancer Ireland](/charles/t4media/microscope-275984 200w200h.jpg)
Investigate the interaction of top-performing non-viral vectors for gene therapy within live system
![Breast Cancer Ireland](/charles/t4media/microscope-275984 200w200h.jpg)
Development Of Gene-Editing Therapy To Restore Type Vii Collagen For The Treatment Of RDEB Using A Topical RNP Crispr System
![Breast Cancer Ireland](/charles/t4media/microscope-275984 200w200h.jpg)
Development of Novel Hyperbranched Poly(β-amino ester)s as a New Generation of Biodegradable Tissue Adhesive
![Breast Cancer Ireland](/charles/t4media/microscope-275984 200w200h.jpg)
Type VII collagen restoration in Recessive Dystrophic Epidermolysis Bullosa using a non-viral CRISPR gene-editing approach
Melanoma and other Skin Cancers Projects
![Breast Cancer Ireland](/charles/t4media/microscope-275984 200w200h.jpg)
Quantitative analysis of signaling pathway rewiring in melanocytes and melanomas mediated by microenvironmental cues and cell intrinsic factors
![Breast Cancer Ireland](/charles/t4media/microscope-275984 200w200h.jpg)
Investigations of the homeo-dynamic status of heterogeneous subpopulations of normal human cutaneous melanocytes: a paradigm for understanding melanoma-genesis.
Hair Growth Biology Projects
![Breast Cancer Ireland](/charles/t4media/microscope-275984 200w200h.jpg)
Discovery of autoantigens that trigger immune-mediated hair loss in Alopecia areata
Skin-Non-Skin Axes Projects
![Breast Cancer Ireland](/charles/t4media/microscope-275984 200w200h.jpg)
Skin biomarker study in Parkinsonian syndromes
Innovation & Consultancy Services Projects
![Breast Cancer Ireland](/charles/t4media/microscope-275984 200w200h.jpg)
Skin & Hair Pigmentation Projects
No active projects currently in this area.