Project Title: Type VII collagen restoration in Recessive Dystrophic Epidermolysis Bullosa using a non-viral CRISPR gene-editing approach
Thematic Area: Rare Skin Diseases
Focus of Research: Gene Therapy
Overview: The main aim of this project is to develop new therapeutic approaches for RDEB based on CRISPR/Cas systems to be delivered into the target cells by hyperbranched cationic polymers (Cat-Polymers).
Funded by: China Scholarship Council
PI: Prof. Wenxin Wang
Other Group/team members: Xianqing Wang
Project Duration: December 2021-December 2024
