January-April 2021
Wall D, Meah N, York K, Bhoyrul B, Bokhari L, Abraham LS, Adams R, Bergfeld W, Betz RC, Blume-Peytavi U, Callender V, Campbell C, Chambers J, Chen G, Chitreddy V, Cotsarelis G, Craiglow B, Dhurat R, Dlova N, Donovan J, Duque-Estrada B, Eisman S, Ellison A, Farrant P, Barberá JF, Gadzhigoroeva A, Grimalt R, Harries M, Hordinsky M, Irvine AD, Jolliffe V, Jones L, King B, Lee WS, Lortkipanidze N, McMichael A, Messenger A, Mirmirani P, Olsen E, Orlow SJ, Ovcharenko Y, Piraccini BM, Pirmez R, Rakowska A, Reygagne P, Riley M, Rudnicka L, Saceda Corralo D, Shapiro J, Sharma P, Silyuk T, Kaiumov S, Tobin DJ, Tosti A, Vañó-Galván S, Vogt A, Wade M, Yip L, Zlotogorski A, Zhou C, Sinclair R. A Global eDelphi Exercise to Identify Core Domains and Domain Items for the Development of a Global Registry of Alopecia Areata Disease Severity and Treatment Safety (GRASS). JAMA Dermatol. 2021 Mar 3. doi: 10.1001/jamadermatol.2020.5839. Epub ahead of print.
Castellano-Pellicena I, Morrison CG, Bell M, O'Connor C, Tobin DJ. Melanin Distribution in Human Skin: Influence of Cytoskeletal, Polarity, and Centrosome-Related Machinery of Stratum basale Keratinocytes. Int J Mol Sci. 2021 Mar 19;22(6):3143. doi: 10.3390/ijms22063143. PMID: 33808676; PMCID: PMC8003549.
O'Sullivan JDB, Nicu C, Picard M, Chéret J, Bedogni B, Tobin DJ, Paus R. The biology of human hair greying. Biol Rev Camb Philos Soc. 2021 Feb;96(1):107-128. doi: 10.1111/brv.12648. Epub 2020 Sep 23. PMID: 32965076.
Bollard SM, Casalou C, Goh CY, Tobin DJ, Kelly P, McCann A, Potter SM. Circulating Melanoma-Derived Extracellular Vesicles: Impact on Melanoma Diagnosis, Progression Monitoring, and Treatment Response. Pharmaceuticals (Basel). 2020 Dec 18;13(12):475. doi: 10.3390/ph13120475 PMID: 33353043; PMCID: PMC7766072.
Tobin DJ. Unpicking the Gordian knot of identifying metastasis development-relevant proteins in cutaneous squamous cell carcinoma. Br J Dermatol. 2020 Dec 16. doi: 10.1111/bjd.19697. Epub ahead of print. PMID: 33325538.
Al-Rikabi AHA, Tobin DJ, Riches-Suman K, Thornton MJ. Dermal fibroblasts cultured from donors with type 2 diabetes mellitus retain an epigenetic memory associated with poor wound healing responses. Sci Rep. 2021 Jan 14;11(1):1474. doi: 10.1038/s41598-020-80072-z PMID: 33446687; PMCID: PMC7809350.
Williams R, Castellano-Pelicena I, Al-Rikabi AHA, Sikkink SK, Baker R, Riches-Suman K, Thornton MJ. Laser Capture Microdissection on Surgical Tissues to Identify Aberrant Gene Expression in Impaired Wound Healing in Type 2 Diabetes. J Vis Exp. 2021 Jan 13;(167). doi: 10.3791/62091. PMID: 33522515.
Lynch M, Malara A, Timoney I, Vencken S, Ahern T, Awdeh F, Sweeney C, Galligan M, Kelly G, Hughes R, Murad A, Hambly R, O'Shea D, Doran P, Kirby B. Sitagliptin and Narrow-Band Ultraviolet-B for Moderate Psoriasis (DINUP): A Randomised Controlled Clinical Trial. Dermatology. 2021 Apr 16:1-8. doi: 10.1159/000514494. Epub ahead of print. PMID: 33866313.
Lynch M, Malara A, Timoney I, Ahern T, Awdeh F, Sweeney C, Galligan M, Venckens S, Kelly G, Hughes R, O Apos Shea D, Doran P, Kirby B. Dipeptidyl Peptidase-4 Inhibition in Psoriasis Patients with Diabetes: A Double-Blind Randomized Controlled Trial. Dermatology. 2021;237(1):66-69. doi: 10.1159/000502130. Epub 2019 Aug 30. PMID: 31473741.
Foley R, Kelly P, Gatault S, Powell F. Demodex: a skin resident in man and his best friend. J Eur Acad Dermatol Venereol. 2021 Jan;35(1):62-72. doi: 10.1111/jdv.16461. Epub 2020 May 15. PMID: 32294279.
Cai, Y., Johnson, M., A, S., Xu, Q.*, Tai, H., Wang, W.*. ‘A Hybrid Injectable and Self-Healable Hydrogel System As 3D Cell Culture Scaffold’. MACROMOLECULAR BIOSCIENCE, 2021, in press.
A, S., Xu, Q., Johnson, M., Creagh-Flynn, J., Venet, M., Zhou, D., Lara-Saez, I., Tai, H., Wang, W. ‘An Injectable Multi-Responsive Hydrogel as Self-Healable and On-demand Dissolution Tissue Adhesive’. APPLIED MATERIALS TODAY, 2021, 22, 100967, DOI: 10.1016/j.apmt.2021.100967.
Newland B, Newland H, Lorenzi F, Eigel D, Welzel PB, Fischer D, Wang W, Freudenberg U, Rosser A, Werner C. Injectable Glycosaminoglycan-Based Cryogels from Well-Defined Microscale Templates for Local Growth Factor Delivery. ACS Chem Neurosci. 2021 Apr 7;12(7):1178-1188. doi: 10.1021/acschemneuro.1c00005. Epub 2021 Mar 23. PMID: 33754692; PMCID: PMC8033563.
López-Cano JJ, Sigen A, Andrés-Guerrero V, Tai H, Bravo-Osuna I, Molina-Martínez IT, Wang W, Herrero-Vanrell R. Thermo-Responsive PLGA-PEG-PLGA Hydrogels as Novel Injectable Platforms for Neuroprotective Combined Therapies in the Treatment of Retinal Degenerative Diseases. Pharmaceutics. 2021 Feb 7;13(2):234. doi: 10.3390/pharmaceutics13020234. PMID: 33562265; PMCID: PMC7915560.
Charles Affiliates
Fahlstedt M, Abayazid F, Panzer MB, Trotta A, Zhao W, Ghajari M, Gilchrist MD, Ji S, Kleiven S, Li X, Annaidh AN, Halldin P. Ranking and Rating Bicycle Helmet Safety Performance in Oblique Impacts Using Eight Different Brain Injury Models. Ann Biomed Eng. 2021 Mar;49(3):1097-1109. doi: 10.1007/s10439-020-02703-w. Epub 2021 Jan 21. PMID: 33475893.
Zouzias D, De Bruyne G, Ni Annaidh A, Trotta A, Ivens J. The effect of the scalp on the effectiveness of bicycle helmets' anti-rotational acceleration technologies. Traffic Inj Prev. 2021;22(1):51-56. doi: 10.1080/15389588.2020.1841179. Epub 2020 Nov 30. PMID: 33252249.
Golbari NM, van der Walt JM, Blauvelt A, Ryan C, van de Kerkhof P, Kimball AB. Psoriasis severity: commonly used clinical thresholds may not adequately convey patient impact. J Eur Acad Dermatol Venereol. 2021 Feb;35(2):417-421. doi: 10.1111/jdv.16966. Epub 2020 Dec 9. PMID: 32978847.
Successful use of Guselkumab in the treatment of severe hidradenitis suppurativa. Kearney N, Byrne N, Kirby B, Hughes R. Clin Exp Dermatol. 2020 Feb 18. doi: 10.1111/ced.14199
Remission of severe hidradenitis suppurativa following chemotherapy for Hodgkin lymphoma.Byrne N, Hughes R, Murphy LA, Kirby B. Br J Dermatol. 2020 Feb;182(2):483-484. doi: 10.1111/bjd.18423. Epub 2019 Oct 9.
Evaluating patients' unmet needs in hidradenitis suppurativa: Results from the Global Survey Of Impact and Healthcare Needs (VOICE) Project. Garg A, Neuren E, Cha D, Kirby JS, Ingram JR, Jemec GBE, Esmann S, Thorlacius L, Villumsen B, Marmol VD, Nassif A, Delage M, Tzellos T, Moseng D, Grimstad Ø, Naik H, Micheletti R, Guilbault S, Miller AP, Hamzavi I, van der Zee H, Prens E, Kappe N, Ardon C, Kirby B, Hughes R, Zouboulis CC, Nikolakis G, Bechara FG, Matusiak L, Szepietowski J, Glowaczewska A, Smith SD, Goldfarb N, Daveluy S, Avgoustou C, Giamarellos-Bourboulis E, Cohen S, Soliman Y, Brant EG, Akilov O, Sayed C, Tan J, Alavi A, Lowes MA, Pascual JC, Riad H, Fisher S, Cohen A, Paek SY, Resnik B, Ju Q, Wang L, Strunk A. J Am Acad Dermatol. 2020 Feb;82(2):366-376. doi: 10.1016/j.jaad.2019.06.1301. Epub 2019 Jul 3.
Recategorization of psoriasis severity: Delphi consensus from the International Psoriasis Council. Strober B, Ryan C, van de Kerkhof P, van der Walt J, Kimball AB, Barker J, Blauvelt A; International Psoriasis Council Board Members and Councilors. J Am Acad Dermatol. 2020 Jan;82(1):117-122. doi: 10.1016/j.jaad.2019.08.026. Epub 2019 Aug 16.
A microstructurally inspired constitutive model for skin mechanics.Chen S, Ní Annaidh A, Roccabianca S. Biomech Model Mechanobiol. 2020 Feb;19(1):275-289. doi:1007/s10237-019-01210-9. Epub 2019 Aug 8.
Complex polymer architectures through free-radical polymerization of multivinyl monomers. Gao, Y., Zhou, D., Lyu J., A, S., Xu, Q., Newland, B., Matyjaszewski, K., Tai, H., Wang, W. Nature Reviews Chemistry, 2020, March 23 doi: 10.1038/s41570-020-0170-7
‘Effects of Branching Strategy on the Gene Transfection of Highly Branched Poly(β-amino ester)s. Wang, Y., Wang, C., Li, M., Zhou, D.*, Huang, W., Wang, W., Yan, D. Chinese Journal of Polymer Science, 2020, DOI: 10.1007/s10118-020-2393-y
Characterization of serotonin and N-acetylserotonin systems in the human epidermis and skin cells. Slominski AT, Kim TK, Kleszczyński K, Semak I, Janjetovic Z, Sweatman T,Skobowiat C, Steketee JD, Lin Z, Postlethwaite A, Li W, Reiter RJ, Tobin DJ.J Pineal Res. 2020 Mar;68(2):e12626. Doi: 10.1111/jpi.12626. Epub 2019 Dec 20.
Bacteria-Resistant Single Chain Cyclized/Knotted Polymer Coatings, Xu, Q., Sigen, A., Wang, W et. al. Angewandte Chemie - International Edition 58(31), pp. 10616-10620, EPub 2019 June 26.
Surface patterning of a novel PEG-functionalized poly-l-lactide polymer to improve its biocompatibility: Applications to bioresorbable vascular stents. Pacharra S, Ortiz R, McMahon S, Wang W, Viebahn R, Salber J, Quintana I. Journal of Biomedical Materials Research - Part B Applied Biomaterials, 107(3), pp. 624-634, 2019 April.
Branched polystyrenes from suspension "strathclyde" polymerization using a vulcanization accelerator as a chain transfer agent. Haiyang Yong, Yongpeng Miao, Sigen A, Dong Quan, Alojz Ivankovic, Krutika Singh, Jing Zhang, Dezhong Zhou, Wenxin Wang. Polymer Chemistry 10(7), pp. 885-890. 2019 Jan 1st.
Rebuilding Postinfarcted Cardiac Functions by Injecting TIIA@PDA Nanoparticle-Cross-linked ROS-Sensitive Hydrogels. Wang W, Chen J, Li M, Jia H, Han X, Zhang J, Zou Y, Tan B, Liang W, Shang Y, Xu Q, A S, Wang W, Mao J, Gao X, Fan G, Liu W. ACS Applied Materials and Interfaces 11(3), pp. 2880-2890. 2019 Jan 10.
Manipulation of Transgene Expression in Fibroblast Cells by a Multifunctional Linear-Branched Hybrid Poly(β-Amino Ester) Synthesized through an Oligomer Combination Approach. Zeng M, Zhou D, Alshehri F, Lara-Sáez I, Lyu Y, Creagh-Flynn J, Xu Q, A S, Zhang J, Wang W. Nano Letters 19(1), pp. 381-391. 2019 Jan 9.
Controlled Polymerization of Methyl Methacrylate and Styrene via Cu(0)-Mediated RDRP by Selecting the Optimal Reaction Conditions. Miao YP, Lyu J, Yong HY, A Sigen, Gao YS, Wang W. Chinese Journal of Polymer Science (English Edition) 2019 March 11
A GWAS in Latin Americans highlights the convergent evolution of lighter skin pigmentation in Eurasia. Adhikari K, Mendoza-Revilla J, Sohail A, Fuentes-Guajardo M, Lampert J, Chacón-Duque JC, Hurtado M, Villegas V, Granja V, Acuña-Alonzo V, Jaramillo C, Arias W, Lozano RB, Everardo P, Gómez-Valdés J, Villamil-Ramírez H, Silva de Cerqueira CC, Hunemeier T, Ramallo V, Schuler-Faccini L, Salzano FM, Gonzalez-José R, Bortolini MC, Canizales-Quinteros S, Gallo C, Poletti G, Bedoya G, Rothhammer F, Tobin DJ, Fumagalli M, Balding D, Ruiz-Linares A. Nat Commun. 2019 Jan 21;10(1):358. doi: 10.1038/s41467-018-08147-0.
Interleukin-4 and interleukin-13 evoke scratching behaviour in mice. Campion M, Smith L, Gatault S, Métais C, Buddenkotte J, Steinhoff M. Exp Dermatol. 2019 Dec;28(12):1501-1504. doi: 10.1111/exd.14034. Epub 2019 Oct 1.
House dust mite-treated PAR2 over-expressor mouse: A novel model of atopic dermatitis. Smith L, Gatault S, Casals-Diaz L, Kelly PA, Camerer E, Métais C, Knaus UG, Eissner G, Steinhoff M. Exp Dermatol. 2019 Nov;28(11):1298-1308. doi: 10.1111/exd.14030. Epub 2019 Sep 17.
TLR3 in Chronic Human Itch: A Keratinocyte-Associated Mechanism of Peripheral Itch Sensitization. Szöllősi AG, McDonald I, Szabó IL, Meng J, van den Bogaard E, Steinhoff M. J Invest Dermatol. 2019 Nov;139(11):2393-2396.e6. doi: 10.1016/j.jid.2019.04.018. Epub 2019 May 24
Pharmacologic inhibition of hypoxia-inducible factor (HIF)-hydroxylases ameliorates allergic contact dermatitis. Manresa MC, Smith L, Casals-Diaz L, Fagundes RR, Brown E, Radhakrishnan P, Murphy SJ, Crifo B, Strowitzki MJ, Halligan DN, van den Bogaard EH, Niehues H, Schneider M, Taylor CT, Steinhoff M. Allergy. 2019 Apr;74(4):753-766. doi: 10.1111/all.13655. Epub 2018 Dec 12.
Evaluation of Demodex mite viability using motility and scattered light intensity. Gatault S, Foley R, Shiels L, Powell FC. Exp Appl Acarol. 2019 Apr;77(4):463-469. doi: 10.1007/s10493-019-00358-4. Epub 2019 Apr 19.
Enhancing survival of Demodex mites in vitro. Shiels L, Foley R, Gatault S, Powell FC. J Eur Acad Dermatol Venereol. 2019 Feb;33(2):e57-e58. doi: 10.1111/jdv.15189. Epub 2018 Aug 14.
Examining Individual Differences in Wellbeing, Anxiety and Depression in Psoriasis Using a Clinically Modified Buddhist Psychological Model. Maddock A, Hevey D, D'Alton P, Kirby B. J Clin Psychol Med Settings. 2019 Dec 4. doi: 10.1007/s10880-019-09686-4.
Enrichment of Plasma Cells in the Peripheral Blood and Skin of Patients with Hidradenitis Suppurativa. Musilova J, Moran B, Sweeney CM, Malara A, Zaborowski A, Hughes R, Winter DC, Fletcher JM, Kirby B. J Invest Dermatol. 2019 Nov 1. pii: S0022-202X(19)33374-3. doi: 10.1016/j.jid.2019.08.453. [Epub ahead of print]
Secukinumab for patients failing previous tumour necrosis factor-α inhibitor therapy: results of a randomized open-label study (SIGNATURE).Warren RB, Barker JNWB, Finlay AY, Burden AD, Kirby B, Armendariz Y, Williams R, Hatchard C, Khare S, Griffiths CEM. Br J Dermatol. 2019 Oct 18. doi: 10.1111/bjd.18623. [Epub ahead of print]
Dipeptidyl Peptidase-4 Inhibition in Psoriasis Patients with Diabetes: A Double-Blind Randomized Controlled Trial. Lynch M, Malara A, Timoney I, Ahern T, Awdeh F, Sweeney C, Galligan M, Venckens S, Kelly G, Hughes R, O Apos Shea D, Doran P, Kirby B. Dermatology. 2019 Aug 30:1-4. doi: 10.1159/000502130. [Epub ahead of print]
Validation and psychometric evaluation of a brief screening questionnaire for psychological distress in patients with psoriasis. Nearchou F, D'Alton P, Donnelly A, O'Driscoll L, O'Flanagan S, Kirby B. J Eur Acad Dermatol Venereol. 2019 Jul;33(7):1325-1330. doi: 10.1111/jdv.15612. Epub 2019 May 10.
Prolonged clindamycin and rifampicin for hidradenitis suppurativa: resist to prevent resistance. Hambly R, Kirby B. Br J Dermatol. 2019 Apr;180(4):702-703. doi: 10.1111/bjd.17615.
Metformin use in hidradenitis suppurativa. Jennings L, Hambly R, Hughes R, Moriarty B, Kirby B. J Dermatolog Treat. 2019 Mar 20:1-3. doi: 10.1080/09546634.2019.1592100. [Epub ahead of print]
Investigation of the skin microbiome: swabs vs. biopsies. Prast-Nielsen S, Tobin AM, Adamzik K, Powles A, Hugerth LW, Sweeney C, Kirby B, Engstrand L, Fry L. Br J Dermatol. 2019 Sep;181(3):572-579. doi: 10.1111/bjd.17691. Epub 2019 May 6.
Psychological Distress, Alexithymia and Alcohol Misuse in Patients with Psoriasis: A Cross-Sectional Study. Founta O, Adamzik K, Tobin AM, Kirby B, Hevey D. J Clin Psychol Med Settings. 2019 Jun;26(2):200-219. doi: 10.1007/s10880-018-9580-9.
Clinical considerations for the management of psoriasis in women. Gottlieb AB, Ryan C, Murase JE. Int J Womens Dermatol. 2019 Apr 10;5(3):141-150. doi: 10.1016/j.ijwd.2019.04.021. eCollection 2019 Jul. Review.
Risankizumab compared with adalimumab in patients with moderate-to-severe plaque psoriasis (IMMvent): a randomised, double-blind, active-comparator-controlled phase 3 trial. Reich K, Gooderham M, Thaçi D, Crowley JJ, Ryan C, Krueger JG, Tsai TF, Flack M, Gu Y, Williams DA, Thompson EHZ, Paul C. Lancet. 2019 Aug 17;394(10198):576-586. doi: 10.1016/S0140-6736(19)30952-3. Epub 2019 Jul 4. Erratum in: Lancet. 2019 Jul 16
Genital psoriasis: the failure of dermatologists to identify genital involvement. Ryan C. Br J Dermatol. 2019 Mar;180(3):460-461. doi: 10.1111/bjd.17505.
Mechanical characterisation of human and porcine scalp tissue at dynamic strain rates. Trotta A, Ní Annaidh A. J Mech Behav Biomed Mater. 2019 Dec;100:103381.doi: 10.1016/j.jmbbm.2019.103381. Epub 2019 Aug
Versatile Hyperbranched Poly(β-hydrazide ester) Macromers as Injectable Antioxidative Hydrogels. Xu Q, Venet M, Wang W, Creagh-Flynn J, Wang X, Li X, Gao Y, Zhou D, Zeng M,Lara-Sáez I, A S, Tai H, Wang W. ACS Applied Materials and Interfaces 10(46), pp. 39494-39504. 2018 Nov 21.
Cartilage regeneration using arthroscopic flushing fluid-derived mesenchymal stem cells encapsulated in a one-step rapid cross-linked hydrogel. Li J, Huang Y, Song J, Li X, Zhang X, Zhou Z, Chen D, Ma PX, Peng W, Wang W, Zhou G. 2018. Acta Biomaterialia 79, pp. 202-215. 2018 Oct 1.
Monte Carlo Simulations of Atom Transfer Radical (Homo)polymerization of Divinyl Monomers: Applicability of Flory-Stockmayer Theory. Lyu J, Gao Y, Zhan Z, , Greiser U, Polanowski P, Jeszka JK, Matyjaszewski K, Tai H, Wang W. Macromolecules 2018 51(17), pp. 6673-6681. 2018 Aug 21.
Structural Design of Robust and Biocompatible Photonic Hydrogels from an in Situ Cross-Linked Hyperbranched Polymer System. Zhang, J., Yong, H., A, S., Xu, Q., Miao, Y., Lyu, J., Gao, Y., Zeng, M., Zhou, D.*, Yu, Z., Tai, H., Wang, W. Chemistry of Materials 2018 30(17), pp. 6091-6098. 2018 Aug 21.
Acceleration of Diabetic Wound Regeneration using an In Situ–Formed Stem-Cell-Based Skin Substitute. Dong, Y.*, Rodrigues, M., Kwon, S., Li, X., A, S., Brett, E., Elvassore, N., Wang, W., Gurtner, G. Advanced Healthcare Materials, 2018 7(17),1800432. 2018 Jul 13.
The Effect Acetic Acid has on Poly(N-Vinylcaprolactam) LCST for Biomedical Applications. Dalton, M., Halligan, S., Killion, J., Wang, W., Dong, Y., Nugent, M., Geever, L. Polymer - Plastics Technology and Engineering, 2018 57(12), pp. 1165-1174. 2018 Jan 03.
Bio-resorbable polymer stents: a review of material progress and prospects.
McMahon, S., Bertollo, N., O'Cearbhaill, E., Salber, J., Pierucci, L., Duffy, P., Dürig, T., Bi, V., Wang, W. Progress in Polymer Science, 2018 83, pp. 79-96. 2018 Aug.
A hybrid injectable hydrogel from hyperbranched PEG macromer as a stem cell delivery and retention platform for diabetic wound healing. Xu, Q., A, S., Gao, Y., Guo, L., Creagh-Flynn, J., Zhou, D., Greiser, U., Dong, Y., Wang, F., Tai, H., Liu, W., Wang, W. Acta Biomaterialia 2018 75, pp. 63-74. 2018 May 25
Paintable and Rapidly Bondable Conductive Hydrogels as Therapeutic Cardiac Patches, Liang, S., Zhang, Y., Wang, H., Xu, Z., Chen, J., Bao, R., Tan, B., Cui, Y., Fan, G., Wang, W., Liu, W. Advanced Materials, 2018 30(23),1704235. 2018 Apr 24.
Short poly(ethylene glycol) block initiation of poly(l-lactide) di-block copolymers: a strategy for tuning the degradation of resorbable devices. Azhari, Z., McMahon, S., Pierucci, L., Wang, W., Cameron, R. Polymer International, 2018 67(6), pp. 726-738. 2018 Feb 15.
Double-Cross-Linked Hydrogel Strengthened by UV Irradiation from a Hyperbranched PEG-Based Trifunctional Polymer. Xu, Q., A, S.*, McMichael, P., Creagh-Flynn, J., Zhou, D., Gao, Y., Li, X., Wang, X., Wang, W. ACS Macro Letters, 2018 7(5), pp. 509-513. 2018 April 9.
Brushlike Cationic Polymers with Low Charge Density for Gene Delivery. O'Keeffe Ahern, J., A, S., Zhou, D., Gao, Y., Lyu, J., Meng, Z., Cutlar, L., Pierucci, L., Wang, W. Biomacromolecules, 2018 19(5), pp. 1410-1415
Soft and flexible poly(ethylene glycol) nanotubes for local drug delivery. Newland, B.*, Taplan, C., Pette, D., Friedrichs, J., Steinhart, M., Wang, W., Voit, B., Seib, F. P., Werner, C. Nanoscale, 2018 10(18), pp. 8413-8421. 2018 May 10.
miRNA delivery for skin wound healing. Meng, Z., Zhou, D.*, Gao, Y., Zeng, M., Wang, W. Advanced Drug Delivery Reviews, 2018 129, pp. 308-318. 2018 April.
Can Flory-Stockmayer theory be applied to predict conventional free radical polymerization of multivinyl monomers? A study via Monte Carlo simulations. Lyu, J., Gao, Y.*, Zhang, Z., Greiser, U., Tai, H., Wang, W. Science China Chemistry, 2018 61(3), pp. 319-327.
Catechol functionalized hyperbranched polymers as biomedical materials. Zhang, H., Zhao, T., Newland, B., Liu, W., Wang, W.*, Wang, W. Progress in Polymer Science, 2018 78, pp. 47-55.
A hyperbranched amphiphilic acetal polymer for pH-sensitive drug delivery. Cao, H., Chen, C., Xie, D., Chen, X., Wang, P., Wang, Y., Song, H., Wang, W. Polymer Chemistry 2018, 9(2), pp. 169-177.
A facile one-pot synthesis of acrylated hyaluronic acid. A, S., Xu, Q., McMichael, P.,Gao, Y., Li, X., Wang, X., Greiser, U., Zhou, D., Wang, W. Chemical Communications, 2018 54(9), pp. 1081-1084.
Star Polymers from Single-Chain Cyclized/Knotted Nanoparticles as a Core. Huang, X., Zhou, D., A, S., Gao, Y., Wang, X., Li, X., Xu, Q., Greiser, U., Yin, G., Wang, W. Macromolecular Chemistry and Physics, 2018 219(2),1700473
Structural Design of Robust and Biocompatible Photonic Hydrogels from an in Situ Cross-Linked Hyperbranched Polymer System. Zhang, J., Yong, H., A, S., Xu, Q., Miao, Y., Lyu, J., Gao, Y., Zeng, M., Zhou, D., Yu, Z., Tai, H., Wang, W. Journal of the American Chemical Society 2018
Injectable hyperbranched poly(β-amino ester) hydrogels with on-demand degradation profiles to match wound healing processes. Xu, Q., Guo, L., A, S., Gao, Y., Zhou, D., Greiser, U., Creagh-Flynn, J., Zhang, H., Dong, Y., Cutlar, L., Wang, F., Liu, W., Wang, W, Wang, W. Chemical Science, 2018 9(8), pp. 2179-2187
Early evidence for opposing effects of full versus fragmented adiponectin on melanogenesis in human epidermal melanocytes. Tobin DJ. Br J Dermatol. 2018 Sep;179(3):561-562. doi: 10.1111/bjd.16909.
Role of mast cells and basophils in pruritus. Steinhoff M, Buddenkotte J, Lerner EA. Immunol Rev. 2018 Mar;282(1):248-264. doi: 10.1111/imr.12635. Review.
Rosacea comorbidities and future research: The 2017 update by the National Rosacea Society Expert Committee. Gallo RL, Granstein RD, Kang S, Mannis M, Steinhoff M, Tan J, Thiboutot D. J Am Acad Dermatol. 2018 Jan;78(1):167-170. doi: 10.1016/j.jaad.2017.06.150.
Standard classification and pathophysiology of rosacea: The 2017 update by the National Rosacea Society Expert Committee.Gallo RL, Granstein RD, Kang S, Mannis M, Steinhoff M, Tan J, Thiboutot D. J Am Acad Dermatol. 2018 Jan;78(1):148-155. doi: 10.1016/j.jaad.2017.08.037. Epub 2017 Oct 28. Review.
Mast cells are critical for the limitation of thrombin-induced skin inflammation. Suender CA, Leist M, Åbrink M, Valentin P, Geldmacher A, Steinhoff M, Metz M, Maurer M. Exp Dermatol. 2018 Jan;27(1):50-57. doi: 10.1111/exd.13407. Epub 2017 Oct 19.
Demodex mites modulate sebocyte immune reaction: possible role in the pathogenesis of rosacea.Lacey N, Russell-Hallinan A, Zouboulis CC, Powell FC. Br J Dermatol. 2018 Aug;179(2):420-430. doi: 10.1111/bjd.16540. Epub 2018 Jun 1.
Diagnostic Criteria of Ulcerative Pyoderma Gangrenosum: A Delphi Consensus of International Experts. Maverakis E, Ma C, Shinkai K, Fiorentino D, Callen JP, Wollina U, Marzano AV, Wallach D, Kim K, Schadt C, Ormerod A, Fung MA, Steel A, Patel F, Qin R, Craig F, Williams HC, Powell F, Merleev A, Cheng MY. JAMA Dermatol. 2018 Apr 1;154(4):461-466. doi: 10.1001/jamadermatol.2017.5980.
Clinical use of dimethyl fumarate in moderate-to-severe plaque-type psoriasis: a European expert consensus. Mrowietz U, Barker J, Boehncke WH, Iversen L, Kirby B, Naldi L, Reich K,Tanew A, van de Kerkhof PCM, Warren RB. J Eur Acad Dermatol Venereol. 2018 Oct;32 Suppl 3:3-14. doi: 10.1111/jdv.15218. Epub 2018 Sep 20.
Naturally derived Heme-Oxygenase 1 inducers attenuate inflammatory responses in human dendritic cells and T cells: relevance for psoriasis treatment. Campbell NK, Fitzgerald HK, Malara A, Hambly R, Sweeney CM, Kirby B, Fletcher JM, Dunne A. Sci Rep. 2018 Jul 6;8(1):10287. doi: 10.1038/s41598-018-28488-6.
The Development of a Patient-Reported Outcome Measure for Assessment of Genital Psoriasis Symptoms: The Genital Psoriasis Symptoms Scale (GPSS).Gottlieb AB, Kirby B, Ryan C, Naegeli AN, Burge R, Potts Bleakman A, Anatchkova MD, Yosipovitch G. Dermatol Ther (Heidelb). 2018 Mar;8(1):45-56. doi: 10.1007/s13555-017-0213-2. Epub 2017 Dec 4.
The Development of the Genital Psoriasis Sexual Frequency Questionnaire (GenPs-SFQ) to Assess the Impact of Genital Psoriasis on Sexual Health.Gottlieb AB, Kirby B, Ryan C, Naegeli AN, Burge R, Potts Bleakman A, Anatchkova MD, Cather J. Dermatol Ther (Heidelb). 2018 Mar;8(1):33-44. doi: 10.1007/s13555-017-0212-3. Epub 2017 Dec 4.
Medication adherence among patients with psoriasis on traditional systemic and biologics treatment.Hambly R, Kelly A, Gilhooley E, Nic Dhonncha E, Murad A, Hughes R, Lally A, Kirby B.Br J Dermatol. 2018 Jan;178(1):e46-e48. doi: 10.1111/bjd.15856. Epub 2017 Dec 12. No abstract available.
Trotta A, Zouzias D, De Bruyne G, Ní Annaidh A. The Importance of the Scalp in
Head Impact Kinematics. Ann Biomed Eng. 2018 Jun;46(6):831-840. doi:1007/s10439-018-2003-0. Epub 2018 Mar 1. PubMed PMID: 29497893.
Trotta A, Ní Annaidh A, Burek RO, Pelgrims B, Ivens J. Evaluation of the
head-helmet sliding properties in an impact test. J Biomech. 2018 Jun
25;75:28-34. doi: 10.1016/j.jbiomech.2018.05.003. Epub 2018 May 18. PubMed PMID:
A new developing class of gene delivery: Messenger RNA-based therapeutics.Meng, Z., O'Keeffe Ahern, J., Lyu, J., Pierucci, L., Zhou, D, Wang, W. Biomaterials Science, 2017 5(12), pp. 2381-2392
Synthesis, characterisation and phase transition behaviour of temperature-responsive physically crosslinked poly (N-vinylcaprolactam) based polymers for biomedical applications. Halligana, S., Daltona, M., Murraya, K., Dong, Y., Wang, W., Lyonsa, J., Geevera, L. Materials Science and Engineering: C, 2017, 79, pp. 130-139
Thermoresponsive and reducible hyperbranched polymers synthesized by RAFT polymerisation. Tochwin, A., El-Betany, A., Tai, H., Chan, K., Blackburn, C., Wang, W. Polymers, 2017, 9(9),443
Biodegradable Highly Branched Poly(β-Amino Ester)s for Targeted Cancer Cell Gene Transfection. Liu, S., Gao, Y., A, S., Zhou, D., Greiser, U., Guo, T., Wang, W. ACS Biomaterials Science and Engineering, 2017, p. 1283-1286
Injectable and Tunable Gelatin Hydrogels Enhance Stem Cell Retention and Improve Cutaneous Wound Healing. Dong, Y., A, S., Rodrigues, M., Li, X., Kwon, S., Kosaric, N., Khong, S., Gao, Y., Wang, W., Gurtner, G. Advanced Functional Materials, 2017, 27(24),1606619
Star Poly(β-amino esters) Obtained from the Combination of Linear Poly(β-amino esters) and Polyethylenimine. Huang, X., Zhou, D., Zeng, M., Alshehri, F., Li, X., O'Keeffe Ahern, J., Gao, Y., Pierucci, L., Greiser, U., Yin, G., Wang, W. ACS Macro Letters, 2017, 6(6), pp. 575-579
Biodegradable and biocompatible PDLLA-PEG1k-PDLLA diacrylate macromers: Synthesis, characterisation and preparation of soluble hyperbranched polymers and crosslinked hydrogels. Hughes, A., Tai, H., Tochwin, A., Wang, W. Processes, 2017, 5(2),18.
Highly branched poly(5-amino-1-pentanol-co-1, 4butanediol diacrylate) for high performance gene transfection. Zeng, M., Zhou, D., Ng, S., O'Keeffe Ahern, J., Alshehri, F., Gao, Y., Pierucci, L., Greiser, U., Wang, W. Polymers, 2017, 9(5),161.
Hyperbranched PEG-based multi-NHS polymer and bioconjugation with BSA. A, S., Xu, Q., Zhou, D., Gao, Y., Vasquez, J., Greiser, U., Wang, W., Liu, W., Wang, W. Polymer Chemistry, 2017, 8(8), pp. 1283-1287
Thermo- and pH-Responsive, Coacervate-Forming Hyperbranched Poly(β-amino ester)s for Selective Cell Binding. Zhou, D., Pierucci, L., Gao, Y., O'Keeffe Ahern, J., Huang, X., A, S., Wang, W. ACS Applied Materials and Interfaces, 2017, 9(7), pp. 5793-5802
Viscoelastic study of single chain cyclized polymeric nanoparticles and linear polymers blends. Li, S., Guo, L., Gao, Y., Zhou, D., Wang, W. Acta Polymerica Sinica, 2017, (2), pp. 386-392
Controlled Polymerization of Multivinyl Monomers: Formation of Cyclized/Knotted Single-Chain Polymer Architectures. Gao, Y., Newland, B., Zhou, D., Matyjaszewski, K., Wang, W. Angewandte Chemie - International Edition, 2017, 56(2), pp. 450-460
FRT - FONDATION RENE TOURAINE: An International Foundation For Dermatology.Carstens E, Schmelz M, Hunter HJA, Lerner EA, Misery L, Steinhoff M, Yosipovitch G, Ständer S. Exp Dermatol. 2017 Oct;26(10):972-985. doi: 10.1111/exd.13406.
Synergistic antipruritic effects of gamma aminobutyric acid A and B agonists in a mouse model of atopic dermatitis.Cevikbas F, Braz JM, Wang X, Solorzano C, Sulk M, Buhl T, Steinhoff M, Basbaum AI. J Allergy Clin Immunol. 2017 Aug;140(2):454-464.e2. doi: 10.1016/j.jaci.2017.02.001. Epub 2017 Feb 2
Emerging strategies for the diagnosis and treatment of meibomian gland dysfunction: Proceedings of the OCEAN group meeting.Geerling G, Baudouin C, Aragona P, Rolando M, Boboridis KG, Benítez-Del-Castillo JM, Akova YA, Merayo-Lloves J, Labetoulle M, Steinhoff M, Messmer EM. Ocul Surf. 2017 Apr;15(2):179-192. doi: 10.1016/j.jtos.2017.01.006. Epub 2017 Jan 27.
Shortcomings in rosacea diagnosis and classification. Tan J, Steinhoff M, Berg M, Del Rosso J, Layton A, Leyden J, Schauber J, Schaller M, Cribier B, Thiboutot D, Webster G; Rosacea International Study Group. Br J Dermatol. 2017 Jan;176(1):197-199. doi: 10.1111/bjd.14819.
Rosacea treatment update: recommendations from the global ROSacea COnsensus (ROSCO) panel.Schaller M, Almeida LM, Bewley A, Cribier B, Dlova NC, Kautz G, Mannis M, Oon HH, Rajagopalan M, Steinhoff M, Thiboutot D, Troielli P, Webster G, Wu Y, van Zuuren E, Tan J.Br J Dermatol. 2017 Feb;176(2):465-471. doi: 10.1111/bjd.15173. Epub 2017 Feb 5.
Updating the diagnosis, classification and assessment of rosacea: recommendations from the global ROSacea COnsensus (ROSCO) panel.Tan J, Almeida LM, Bewley A, Cribier B, Dlova NC, Gallo R, Kautz G, Mannis M, Oon HH, Rajagopalan M, Steinhoff M, Thiboutot D, Troielli P, Webster G, Wu Y, van Zuuren EJ, Schaller M. Br J Dermatol. 2017 Feb;176(2):431-438. doi: 10.1111/bjd.15122. Epub 2017 Jan 23.
Involvement of TRPV1 and TDAG8 in Pruriception Associated with Noxious Acidosis.Lin SH, Steinhoff M, Ikoma A, Chang YC, Cheng YR, Chandra Kopparaju R, Ishii S, Sun WH, Chen CC. J Invest Dermatol. 2017 Jan;137(1):170-178. doi: 10.1016/j.jid.2016.07.037. Epub 2016 Aug 24.
Integrative concepts of rosacea pathophysiology, clinical presentation and new therapeutics. Holmes AD, Steinhoff M. Exp Dermatol. 2017 Aug;26(8):659-667. doi: 10.1111/exd.13143. Epub 2016 Oct 9. Review.
Demodex and rosacea revisited. Moran EM, Foley R, Powell FC. Clin Dermatol. 2017 Mar - Apr;35(2):195-200. doi: 10.1016/j.clindermatol.2016.10.014. Epub 2016 Oct 27.
Drug survival of methotrexate in psoriasis. Kirby B. Br J Dermatol. 2017 Aug;177(2):345-346. doi: 10.1111/bjd.15693.
The relevance of serum vitamin D in psoriasis: a review .H ambly R, Kirby B. Arch Dermatol Res. 2017 Sep;309(7):499-517. doi: 10.1007/s00403-017-1751-2. Epub 2017 Jul 3. Review.
Hidradenitis Suppurativa Is Characterized by Dysregulation of the Th17:Treg Cell Axis, Which Is Corrected by Anti-TNF Therapy.Moran B, Sweeney CM, Hughes R, Malara A, Kirthi S, Tobin AM, Kirby B, Fletcher JM. J Invest Dermatol. 2017 Nov;137(11):2389-2395. doi: 10.1016/j.jid.2017.05.033. Epub 2017 Jun 23.
Progressive multifocal leucoencephalopathy and psoriasis. Molloy OE, Foley CC, Lally A, Moriarty B, Collins P, O'Gorman J, de Gascun CF, Kirby B. Br J Dermatol. 2017 Jul;177(1):271-272. doi: 10.1111/bjd.15028. Epub 2017 Jun 5. No abstract available.
Natural killer cells from psoriasis vulgaris patients have reduced levels of cytotoxicity associated degranulation and cytokine production. Dunphy SE, Sweeney CM, Kelly G, Tobin AM, Kirby B, Gardiner CM. Clin Immunol. 2017 Apr;177:43-49. doi: 10.1016/j.clim.2015.10.004. Epub 2015 Oct 20.
Main-chain degradable single-chain cyclized polymers as gene delivery vectors. Gao, Y., Böhmera, V., Zhou, D., Zhao, T., Wang, W. Journal of Controlled Release, 2016, 244, pp. 375-383
Highly branched poly(β-amino ester)s for skin gene therapy. Zhou, D., Gao Y., Aied, A., Cutlar, L., Igoucheva, O., Newland, B., Alexeeve, V., Greiser, U., Uitto, J., Wang, W. Journal of Controlled Release, 2016, 244, pp. 336-346
Development of Branched Poly(5-Amino-1-pentanol-co-1,4-butanediol Diacrylate) with High Gene Transfection Potency Across Diverse Cell Types. Zhou, D., Gao, Y., O'Keeffe Ahern, J., A, S., Xu, Q., Huang, X., Greiser, U., Wang, W. ACS Applied Materials and Interfaces, 2016, 8(50), pp. 34218-34226.
Non-viral xylosyltransferase-1 siRNA delivery as an effective alternative to chondroitinase in an in vitro model of reactive astrocytes. Abu-Rub, M. T., Newland, B., Naughton, M., Wang, W., McMahon, S., & Pandit, A. Neuroscience, 2016, 339, pp. 267-275
Anticancer Drug Disulfiram for in Situ RAFT Polymerization: Controlled Polymerization, Multifacet Self-Assembly, and Efficient Drug Delivery. Zhou, D., Gao, Y., A, S., Xu, Q., Meng, Z., Greiser, U., Wang, W. ACS Macro Letters, 2016, 5(11), pp. 1266-1272
Highly Branched Poly(β-amino esters) for Non-Viral Gene Delivery: High Transfection Efficiency and Low Toxicity Achieved by Increasing Molecular Weight. Gao, Y., Huang, J.Y., O’Keeffe-Ahern, J., Cutlar, L., Zhou, D., Lin, F.H., Wang, W. Biomacromolecules, 2016, 17(11), pp. 3640-3647
Poly(ethylene glycol)-Based Hyperbranched Polymer from RAFT and Its Application as a Silver-Sulfadiazine-Loaded Antibacterial Hydrogel in Wound Care. McMahon, S., Kennedy, R., Duffy, P., Vasquez, J., Wall, J. G., Tai, H., Wang, W. ACS Applied Materials and Interfaces, 2016, 8(40), pp. 26648-26656
A non-viral gene therapy for treatment of recessive dystrophic epidermolysis bullosa. Cutlar, L., Zhou, D., Hu, X., Duarte, B., Greiser, U., Larcher, F., Wang, W. Experimental Dermatology, 2016, 25(10), pp. 818-820.
In situ-formed bioactive hydrogels for delivery of stem cells and biomolecules for wound healing ( Book Chapter). Dong, Y., Wang, W. Wound Healing Biomaterials, 2016, 2, pp. 289-307.
The transition from linear to highly branched poly(β-amino ester)s: Branching matters for gene delivery. Zhou, D., Cutlar, L., Gao, Y., Wang, W., O’Keeffe-Ahern, J., McMahon, S., Duarte, B., Larcher, F., Rodriguez, B.J., Greiser, U., Wang, W. Science Advances, 2016, 2(6)
Synthesis of ROS scavenging microspheres from a dopamine containing poly(β-amino ester) for applications for neurodegenerative disorders. Newland, B., Wolff, P., Zhou, D., Wang, W., Zhang, H., Rosser, A., Wang, W., Werner, C. Biomaterials Science, 2016, 4(3), pp. 400-404.
A hyperbranched dopamine-containing PEG-based polymer for the inhibition of α-synuclein fibrillation. Breydo, L., Newland, B., Zhang, H., Rosser, A., Werner, C., Uversky, V.N., Wang, W. Biochemical and Biophysical Research Communications, 2016, 469(4), pp. 830-835
An acetal-based polymeric crosslinker with controlled pH-sensitivity. Cao, H., Dong, Y., Bre, L., Tapeinos, C., Wang, W., Pandit, A. RSC Advances, 2016, 6(12), pp. 9604-9611.
GSH-responsive polymeric micelles based on the thio-ene reaction for controlled drug release. Cao, H., Huajie, S., Xie, D., Chao, C., Chen, X., Wang, P., Wang, W. RSC Advances, 2016, 6(84), pp. 80896-80904
A knot polymer mediated non-viral gene transfection for skin cells. utlar, L., Aied, A., Gao, Y., Greiser, U., Murauer E. M., Zhou, D., Wang, W. Biomaterials Science, 2016, 4(1), pp. 92-95
Rosacea Management: Update on general measures and topical treatment options. Schaller M, Schöfer H, Homey B, Hofmann M, Gieler U, Lehmann P, Luger TA, Ruzicka T, Steinhoff M. J Dtsch Dermatol Ges. 2016 Dec;14 Suppl 6:17-27. doi: 10.1111/ddg.13143. Review.
Pathogenese und Klinik der Rosazea als Schlüssel für eine symptomorientierte Therapie.Reinholz M, Ruzicka T, Steinhoff M, Schaller M, Gieler U, Schöfer H, Homey B, Lehmann P, Luger TA. J Dtsch Dermatol Ges. 2016 Dec;14 Suppl 6:4-16. doi: 10.1111/ddg.13139_g. Review.
State of the art: systemic rosacea management. Schaller M, Schöfer H, Homey B, Gieler U, Lehmann P, Luger TA, Ruzicka T, Steinhoff M . J Dtsch Dermatol Ges. 2016 Dec;14 Suppl 6:29-37. doi: 10.1111/ddg.13141. Review.
Pathogenesis and clinical presentation of rosacea as a key for a symptom-oriented therapy. Reinholz M, Ruzicka T, Steinhoff M, Schaller M, Gieler U, Schöfer H, Homey B, Lehmann P, Luger TA.J Dtsch Dermatol Ges. 2016 Dec;14 Suppl 6:4-15. doi: 10.1111/ddg.13139. Review.
New light on proteases regulating pigmentation. Smith L, Casals-Diaz L, Steinhoff M. Exp Dermatol. 2016 Nov;25(11):861-862. doi: 10.1111/exd.13090.
Multidisciplinary Consideration of Potential Pathophysiologic Mechanisms of Paradoxical Erythema with Topical Brimonidine Therapy. Docherty JR, Steinhoff M, Lorton D, Detmar M, Schäfer G, Holmes A, Di Nardo A. Adv Ther. 2016 Nov;33(11):1885-1895. Epub 2016 Aug 25. Review.
Topical Ivermectin 10 mg/g and Oral Doxycycline 40 mg Modified-Release: Current Evidence on the Complementary Use of Anti-Inflammatory Rosacea Treatments. Steinhoff M, Vocanson M, Voegel JJ, Hacini-Rachinel F, Schäfer G. Adv Ther. 2016 Sep;33(9):1481-501. doi: 10.1007/s12325-016-0380-z. Epub 2016 Jul 18. Review.
The pruritus- and TH2-associated cytokine IL-31 promotes growth of sensory nerves. Feld M, Garcia R, Buddenkotte J, Katayama S, Lewis K, Muirhead G, Hevezi P, Plesser K, Schrumpf H, Krjutskov K, Sergeeva O, Müller HW, Tsoka S, Kere J, Dillon SR, Steinhoff M, Homey B. n J Allergy Clin Immunol. 2016 Aug;138(2):500-508.e24. doi: 10.1016/j.jaci.2016.02.020. Epub 2016 Apr 6.
TNFα induces co-trafficking of TRPV1/TRPA1 in VAMP1-containing vesicles to the plasmalemma via Munc18-1/syntaxin1/SNAP-25 mediated fusion. Meng J, Wang J, Steinhoff M, Dolly JO. Sci Rep. 2016 Feb 18;6:21226. doi: 10.1038/srep21226.
Involvement of TRPV4 in Serotonin-Evoked Scratching. Akiyama T, Ivanov M, Nagamine M, Davoodi A, Carstens MI, Ikoma A, Cevikbas F, Kempkes C, Buddenkotte J, Steinhoff M, Carstens E. J Invest Dermatol. 2016 Jan;136(1):154-160. doi: 10.1038/JID.2015.388.
Facial Erythema of Rosacea - Aetiology, Different Pathophysiologies and Treatment Options. Steinhoff M, Schmelz M, Schauber J. Acta Derm Venereol. 2016 Jun 15;96(5):579-86. doi: 10.2340/00015555-2335. Review.
Study of Demodex mites: Challenges and Solutions. Lacey N, Russell-Hallinan A, Powell FC. J Eur Acad Dermatol Venereol. 2016 May;30(5):764-75. doi: 10.1111/jdv.13517. Epub 2015 Dec 23. Review.
Is late-onset psoriasis a distinct subtype of chronic plaque psoriasis? Kirby B. Br J Dermatol. 2016 Nov;175(5):869-870. doi: 10.1111/bjd.15035.
Human ß-Defensin 3 and Its Mouse Ortholog Murine ß-Defensin 14 Activate Langerhans Cells and Exacerbate Psoriasis-Like Skin Inflammation in Mice. Sweeney CM, Russell SE, Malara A, Kelly G, Hughes R, Tobin AM, Adamzik K, Walsh PT, Kirby B. J Invest Dermatol. 2016 Mar;136(3):723-727. doi: 10.1016/j.jid.2015.12.011. Epub 2015 Dec 18. No abstract available.
Computational Bench Testing to Evaluate the Short-Term Mechanical Performance of a Polymeric Stent. Bobel, A.C., Petisco, S., Sarasua, J.R., Wang, W., McHugh, P.E. Cardiovascular Engineering and Technology, 2015, 6(4), pp. 519-532
Magnetically Controllable Polymer Nanotubes from a Cyclized Crosslinker for Site-Specific Delivery of Doxorubicin. Newland, B., Leupelt, D., Zheng, Y., Thomas, L.S., Werner, C., Steinhart, M., Wang, W. Scientific Reports, 2015, 5,17478
Hydrolytically Degradable Hyperbranched PEG-Polyester Adhesive with Low Swelling and Robust Mechanical Properties. Zhang, H., Zhao, T., Duffy, P., Dong, Y., Annaidh, A. N., O’Cearbhaill, E., Wang, W. Advanced Healthcare Materials, 2015, 4(15), pp. 2260-2268
Intramolecular Cyclization Dominating Homopolymerization of Multivinyl Monomers toward Single-Chain Cyclized/Knotted Polymeric Nanoparticles. Gao, Y., Zhou, D., Zhao, T., Wei, X., McMahon, S., O’Keeffe-Ahern, J., Wang， W., Greiser, U., Rodriguez, B., Wang, W. Macromolecules, 2015, 48(19), pp. 6882-6889
Highly Branched Poly(β-Amino Esters): Synthesis and Application in Gene Delivery. Cutlar, L., Zhou, D., Gao, Y., Zhao, Y., Greiser, U., Wang, W., Wang, W. Biomacromolecules, 16(9), pp. 2609-2617
A rapid crosslinking injectable hydrogel for stem cell delivery, from multifunctional hyperbranched polymers via RAFT homopolymerization of PEGDA. Dong, Y., Qin, Y., Dubaa M., Killion, J, Gao, Y., Zhao, T., Zhou, D., Duscher, D., Geever, L., Gurtner, G., Wang, W. Polymer Chemistry, 2015, 6(34), pp. 6182-6192
On-demand and negative-thermo-swelling tissue adhesive based on highly branched ambivalent PEG-catechol copolymers. Zhang, H., Zhao, T., Newland, B., Duffy, P., Annaidh, A., O'Cearbhaill, E., Wang, W. Journal of Materials Chemistry B, 2015, 3(31), pp. 6420-6428
Supramolecular Fluorescent Nanoparticles Constructed via Multiple Non-Covalent Interactions for the Detection of Hydrogen Peroxide in Cancer Cells. Wei, X., Dong, R., Wang, D., Zhao, T,. Gao, Y., Duffy, P., Zhu, X.,* Wang, W. Chemistry - A European Journal, 2015, 21(32), pp. 11427-11434
Insights into relevant mechanistic aspects about the induction period of Cu0/Me6TREN-mediated reversible-deactivation radical polymerization, Gao, Y., Zhao, T., Zhou, D., Greiser, U., Wang, W. Chemical Communications, 2015, 51(77), pp. 14435-14438
Supramolecularly engineered phospholipids constructed by nucleobase molecular recognition: upgraded generation of phospholipids for drug delivery, Wang, D., Tu, C., Su, Y., Zhang, C., Greiser, U., Zhu, X., Yan, D., Wang, W. Chemical Science, 2015, 6(7), pp. 3775-3787
Tailoring highly branched poly(β-amino ester)s: A synthetic platform for epidermal gene therapy. Huang, J.Y., Gao, Y., Cutlar, L., O’Keeffe-Ahern, J., Zhao, T., Lin, F.H., Zhou, D., McMahon, S., Greiser, U., Wang, W., Wang, W. Chemical Communications, 2015, 51(40), pp. 8473-8476
Prospects for polymer therapeutics in Parkinson's disease and other neurodegenerative disorders. Newland, B., Newland, H., Werner, C., Rosser, A., Wang, W. Progress in Polymer Science, 2015, 44, pp. 79-112
Synthesis of polymer-silica hybrid microparticles with defined geometry using surface initiated atom transfer radical polymerization. Lang, Y., del Monte, F., Finn, D. P.,Wang, W., Pandit, A. Polymer Chemistry, 2015, 6(16), pp. 3014-3017
Bioapplications of hyperbranched polymers. Wang, D., Zhao, T., Zhu, X., Yan, D., Wang, W. Chemical Society Reviews, 2015, Chemical Society Reviews, 44(12), pp. 4023-4071
Hydrogels from dextran and soybean oil by UV photo-polymerization. Omer, R. A., Hughes, A., Hama J. R., Wang, W. and Tai, H. Journal of Applied Polymer Science, 132(6),41446.
Water soluble hyperbranched polymers from controlled radical homopolymerization of PEG diacrylate. Zhao, T., Zhang, H., Zhou, D., Gao, Y., Dong, Y., Greiser, U., Tai, H., Wang, W. RSC Advances, 2015, 5(43), pp. 33823-33830.
Intradermal endothelin-1 excites bombesin-responsive superficial dorsal horn neurons in the mouse. Akiyama T, Nagamine M, Davoodi A, Iodi Carstens M, Cevikbas F, Steinhoff M, Carstens E. J Neurophysiol. 2015 Oct;114(4):2528-34. doi: 10.1152/jn.00723.2015. Epub 2015 Aug 26.
Pituitary Adenylate Cyclase-Activating Polypeptide Is Upregulated in Murine Skin Inflammation and Mediates Transient Receptor Potential Vanilloid-1-Induced Neurogenic Edema.Helyes Z, Kun J, Dobrosi N, Sándor K, Németh J, Perkecz A, Pintér E, Szabadfi K, Gaszner B, Tékus V, Szolcsányi J, Steinhoff M, Hashimoto H, Reglődi D, Bíró T. J Invest Dermatol. 2015 Sep;135(9):2209-2218. doi: 10.1038/jid.2015.156. Epub 2015 Apr 23.
Role of cytokines and chemokines in itch. Storan ER, O'Gorman SM, McDonald ID, Steinhoff M. Handb Exp Pharmacol. 2015;226:163-76. doi: 10.1007/978-3-662-44605-8_9. Review.
Molecular and Morphological Characterization of Inflammatory Infiltrate in Rosacea Reveals Activation of Th1/Th17 Pathways. Buhl T, Sulk M, Nowak P, Buddenkotte J, McDonald I, Aubert J, Carlavan I, Déret S, Reiniche P, Rivier M, Voegel JJ, Steinhoff M. J Invest Dermatol. 2015 Sep;135(9):2198-2208. doi: 10.1038/jid.2015.141. Epub 2015 Apr 7.
Understanding rosacea. Powell FC. Br J Dermatol. 2015 Sep;173(3):635-7. doi: 10.1111/bjd.14058.
Dysregulated cytokine expression in lesional and nonlesional skin in hidradenitis suppurativa. Kelly G, Hughes R, McGarry T, van den Born M, Adamzik K, Fitzgerald R, Lawlor C, Tobin AM, Sweeney CM, Kirby B. Br J Dermatol. 2015 Dec;173(6):1431-9. doi: 10.1111/bjd.14075. Epub 2015 Nov 17.
Diagnostic delay in hidradenitis suppurativa is a global problem. Saunte DM, Boer J, Stratigos A, Szepietowski JC, Hamzavi I, Kim KH, Zarchi K, Antoniou C, Matusiak L, Lim HW, Williams M, Kwon HH, Gürer MA, Mammadova F, Kaminsky A, Prens E, van der Zee HH, Bettoli V, Zauli S, Hafner J, Lauchli S, French LE, Riad H, El-Domyati M, Abdel-Wahab H, Kirby B, Kelly G, Calderon P, del Marmol V, Benhadou F, Revuz J, Zouboulis CC, Karagiannidis I, Sartorius K, Hagströmer L, McMeniman E, Ong N, Dolenc-Voljc M, Mokos ZB, Borradori L, Hunger RE, Sladden C, Scheinfeld N, Moftah N, Emtestam L, Lapins J, Doss N, Kurokawa I, Jemec GB. Br J Dermatol. 2015, Dec;173(6):1546-9. doi: 10.1111/bjd.14038. Epub 2015 Nov 3.
Psoriasis is a systemic disease with multiple cardiovascular and metabolic comorbidities.Ryan C, Kirby B. Dermatol Clin. 2015 Jan;33(1):41-55. doi: 10.1016/j.det.2014.09.004. Review.
Acetal-linked branched poly(dimethyl-aminoethyl methacrylate) as an acid cleavable gene vector with reduced cytotoxicity. Cao, H. L.*, Dong, Y. X., Aied, A., Zhao, T. Y., Chen, X., Wang, W. X., and Pandit, A. Chemical Communications, 2014, 50(98), pp. 15565-15568
Beyond branching: Multiknot structured polymer for gene delivery. Aied, A., Zheng, Y., Newland, B., Wang, W. Biomacromolecules, 2014, 15(12), pp. 4520-4527
A biomimetic hyperbranched poly(amino ester)-based nanocomposite as a tunable bone adhesive for sternal closure. Zhang, H., Bre, L., Zhao, T., Newland, B., Da Costa, M., Wang, W. Journal of Materials Chemistry B, 2014, 2(26), pp. 4067-4071
Untying a nanoscale knotted polymer structure to linear chains for efficient gene delivery in vitro and to the brain. Newland B, Aied A, Pinoncely AV, Zheng Y, Zhao T, Zhang H, Niemeier R, Dowd E,Pandit A, Wang W. Nanoscale, 2014, 6(13), pp. 7526-7533.
Significance of branching for transfection: Synthesis of highly branched degradable functional poly(dimethylaminoethyl methacrylate) by vinyl oligomer combination. Zhao, T., Zhang, H., Newland, B., Aied, A., Zhou, D., Wang, W. Angewandte Chemie - International Edition, 2014, 53(24), pp. 6095-6100
In situ formed hybrid hydrogels from PEG based multifunctional hyperbranched copolymers: A RAFT approach. Kennedy, R., Hassan, W., Tochwin, A., Zhao, T., Dong, Y., Wang, Q., Tai, H., Wang, W. Polymer Chemistry, 2014, 5(6), pp. 1838-1842
Nano-structured polymer-silica composite derived from a marine diatom via deactivation enhanced atom transfer radical polymerization grafting. O’Connor, J., Lang, Y., Chao, J., Cao, H., Collins, L., Rodriguez, B.J., Dockery, P., Finn, D.P., Wang, W., Pandit, A. Small, 2014, 10(3), pp. 469-473
Is it ATRP or SET-LRP? Part I: Cu0&CuII/PMDETA-mediated reversible-deactivation radical polymerization. Gao, Y., Tianyu Zhao, Y., Wang, W. RSC Advances, 2014, (106), pp. 61687-61690
Prevention of bioprosthetic heart valve calcification: Strategies and outcomes. Bré, L., McCarthy, R., Wang, W. Current Medicinal Chemistry, 2014, 21(22), pp. 2553-2564
Role of adipose-derived stem cells in wound healing. Hassan, W., Greiser, U., Wang, W. Wound Repair and Regeneration, 2014, 22(3), pp. 313-325
Gene therapy: Pursuing restoration of dermal adhesion in recessive dystrophic epidermolysis bullosa. Cutlar, L., Greiser, U., Wang, W. Experimental Dermatology, 23(1), pp. 1-6
A new generation of poly(lactide/ε-caprolactone) polymeric biomaterials for application in the medical field. Fernández, J., Larrañaga, A., Etxeberria, A., Wang, W. Journal of Biomedical Materials Research - Part A, 2014, 102(10), pp. 3573-3584.
Mussel-inspired hyperbranched poly(amino ester) polymer as strong wet tissue adhesive, Zhang, H., Bré, L., Zhao, T., Zheng, Y, Newland, B., Wang, W. Biomaterials, 2014, 35(2), pp. 711-719
Performance of an in situ formed bioactive hydrogel dressing from a PEG-based hyperbranched multifunctional copolymer. Dong, Y., Hassan, W., Kennedy, R., Greiser, U., Pandit, A., Garcia, Y., Wang, W. Acta Biomaterialia, 2014, 10(5), pp. 2076-2085
Continual exposure to cigarette smoke extracts induces tumor-like transformation of human nontumor bronchial epithelial cells in a microfluidic chip. Li, E., Xu, Z., Liu, F., Wang, H., Wen, J., Shao, S., Zhang, L., Wang, L., Liu, C., Lu, J., Wang, W., Gao, Z.*, Wang, Q. Journal of Thoracic Oncology, 2014, 9(8), pp. 1091-1100.
The bile acid receptor TGR5 activates the TRPA1 channel to induce itch in mice.Lieu T, Jayaweera G, Zhao P, Poole DP, Jensen D, Grace M, McIntyre P, Bron R, Wilson YM, Krappitz M, Haerteis S, Korbmacher C, Steinhoff MS, Nassini R, Materazzi S, Geppetti P, Corvera CU, Bunnett NW. Gastroenterology. 2014, Dec;147(6):1417-28. doi: 10.1053/j.gastro.2014.08.042. Epub 2014 Sep 3.
Keratinocyte growth regulation TRP-ed up over downregulated TRPV4? Liedtke W, Zhang JY, Hall RP 3rd, Steinhoff M. J Invest Dermatol. 2014 Sep;134(9):2310-2312. doi: 10.1038/jid.2014.250.
Epidermal hydration levels in patients with rosacea improve after minocycline therapy. Ní Raghallaigh S, Powell FC. Br J Dermatol. 2014 Aug;171(2):259-66. doi: 10.1111/bjd.12770. Epub 2014 Jun 5.
AP1S3 mutations are associated with pustular psoriasis and impaired Toll-like receptor 3 trafficking. Setta-Kaffetzi N, Simpson MA, Navarini AA, Patel VM, Lu HC, Allen MH, Duckworth M, Bachelez H, Burden AD, Choon SE, Griffiths CE, Kirby B, Kolios A, Seyger MM, Prins C, Smahi A, Trembath RC, Fraternali F, Smith CH, Barker JN, Capon F. Am J Hum Genet. 2014 May 1;94(5):790-7. doi: 10.1016/j.ajhg.2014.04.005.
Is universal screening for hepatitis C infection prior to commencing antitumour necrosis factor-α therapy necessary?Reid CT, De Gascun C, Hall W, Collins P, Lally A, Kirby B.
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Interventions for 'rosacea'. Powell FC, Ni Raghallaigh S Br J Dermatol. 2011 Oct;165(4):707-8. doi: 10.1111/j.1365-2133.2011.10590.x.
Glucagon-like peptide-1 (GLP-1) and the regulation of human invariant natural killer T cells: lessons from obesity, diabetes and psoriasis.Hogan AE, Tobin AM, Ahern T, Corrigan MA, Gaoatswe G, Jackson R, O'Reilly V, Lynch L, Doherty DG, Moynagh PN, Kirby B, O'Connell J, O'Shea D. Diabetologia. 2011 Nov;54(11):2745-54. doi: 10.1007/s00125-011-2232-3. Epub 2011 Jul 9.