Explore UCD

UCD Home >

Publications

UCD Conway SPHERE Publication List

2021

  1. Laura Twomey, Nastassia Navasiolava, Adrien Robin, Marie-Pierre Bareille, Guillemette Gauquelin-Koch, Arnaud Beck, Françoise Larcher, Gerardene Meade-Murphy, Sinead Sheridan, Patricia B. Maguire, Michael Harrison, Bernard Degryse, Niall M. Moyna, Claude Gharib, Marc-Antoine Custaud & Ronan P. Murphy A dry immersion model of microgravity modulates platelet phenotype, miRNA signature, and circulating plasma protein biomarker profile. Sci Rep 11, 21906 (2021). (opens in a new window)https://doi.org/10.1038/s41598-021-01335-x
  2. D. Swan, H. Enright, R. Desmond, G. Le, E. El Hassadi, B. Hennessy, F. Lynott, D. O'Keeffe, M. Crowley, L. Smyth, K. Perera, C. Jennings, F. Ni Ainle, J. Coll, K. Ryan, J. O'Donnell, M. Lavin, N. O'Connell, Vaccine-induced thrombosis and thrombocytopenia (VITT) in Ireland: A review of cases and current practices, Thrombosis Update, 2021, 100086, ISSN 2666-5727, (opens in a new window)https://doi.org/10.1016/j.tru.2021.100086.
  3. O’Reilly, D., Murphy, C.A., Drew, R. et al. Platelets in pediatric and neonatal sepsis: novel mediators of the inflammatory cascade. Pediatr Res (2021).
  4. Kelliher, S. and Falanga, A., 2021. Thrombosis in myeloproliferative neoplasms: A clinical and pathophysiological perspective. Thrombosis Update, p.100081. 
  5. Sholzberg, M., Tang, G.H., Rahhal, H., AlHamzah, M., Kreuziger, L.B., Áinle, F.N., Alomran, F., Alayed, K., Alsheef, M., AlSumait, F. and Pompilio, C.E., 2021. Effectiveness of therapeutic heparin versus prophylactic heparin on death, mechanical ventilation, or intensive care unit admission in moderately ill patients with covid-19 admitted to hospital: RAPID randomised clinical trial. bmj, 375.
  6. Cullivan S, McCormack C, O’Callaghan M, et al. Characteristics of chronic thromboembolic pulmonary hypertension in Ireland. Pulmonary Circulation. October 2021. doi:(opens in a new window)10.1177/2045894021104870
  7. Murphy CA, O'Reilly DP, Edebiri O, Weiss L, Cullivan S, El-Khuffash A, Doyle E, Donnelly JC, Malone FD, Ferguson W, Drew RJ, O'Loughlin J, Neary E, Maguire PB, Kevane B, NíAinle F, McCallion N. Haematological parameters and coagulation in umbilical cord blood following COVID-19 infection in pregnancy. (opens in a new window)Eur J Obstet Gynecol Reprod Biol. 2021 Sep 21;266:99-105. doi: 10.1016/j.ejogrb.2021.09.019. Epub ahead of print. PMID: 34601263; PMCID: PMC8454187.
  8. Cullivan, S., Murphy, C. A., Weiss, L., Comer, S. P., Kevane, B., McCullagh, B., Maguire, P. B., Ainle, F.N., & Gaine, S. P. (2021). Platelets, extracellular vesicles and coagulation in pulmonary arterial hypertension. Pulmonary Circulation, 11(3), https://doi.org/10.1177/20458940211021036
  9. Comer, S. P., Cullivan, S., Szklanna, P. B., Weiss, L., Cullen, S., Kelliher, S., Smolenski, A., Murphy, C., Altaie, H., Curran, J., O'Reilly, K., Cotter, A. G., Marsh, B., Gaine, S., Mallon, P., McCullagh, B., Moran, N., Ainle, F. N., Kevane, B., Maguire, P. B., & Investigators, C. S. (2021). COVID-19 induces a hyperactive phenotype in circulating platelets. Plos Biology, 19(2), Article e3001109. (opens in a new window)https://doi.org/10.1371/journal.pbio.3001109
  10. Cremer, S. E., Catalfamo, J. L., Goggs, R., Seemann, S. E., Kristensen, A. T., Szklanna, P. B., Maguire, P. B., & Brooks, M. B. (2021). The canine activated platelet secretome (CAPS): A translational model of thrombin-evoked platelet activation response. Research and Practice in Thrombosis and Haemostasis, 5(1), 55-68. (opens in a new window)https://doi.org/10.1002/rth2.12450
  11. Othman, M., Cormier, M., Barnes, G. D., Comer, S. P., Connors, J. M., Denorme, F., Khorana, A. A., Casas, P. H. L., Morla, S., Muia, J., Ainle, F. N., Taylor, K. A., van der Wal, D. E., Weyand, A. C., Lavin, M., Registration, I., & Mkt, T. (2021). Harnessing Twitter to empower scientific engagement and communication: The ISTH 2020 virtual congress experience. Research and Practice in Thrombosis and Haemostasis, 5(2), 253-260. (opens in a new window)https://doi.org/10.1002/rth2.12478
  12. Sholzberg, M., Tang, G. H., Negri, E., Rahhal, H., Kreuziger, L. B., Pompilio, C. E., James, P., Fralick, M., AlHamzah, M., Alomran, F., Tseng, E., Lim, G., Lillicrap, D., Carrier, M., Ainle, F. N., Beckett, A., da Costa, B. R., Thorpe, K., Middeldorp, S., Lee, A., Cushman, M., & Juni, P. (2021). Coagulopathy of hospitalised COVID-19: A Pragmatic Randomised Controlled Trial of Therapeutic Anticoagulation versus Standard Care as a Rapid Response to the COVID-19 Pandemic (RAPID COVID COAG - RAPID Trial): A structured summary of a study protocol for a randomized controlled trial. Trials, 22(1), Article 202. (opens in a new window)https://doi.org/10.1186/s13063-021-05076-0
  13. Klok FA, Ageno W, Ay C, Bäck M, Barco S, Bertoletti L, Becattini C, Carlsen J, Delcroix M, van Es N, Huisman MV, Jara-Palomares L, Konstantinides S, Lang I, Meyer G, Ní Áinle F, Rosenkranz S, Pruszczyk P. State of the Art Review: "Optimal follow-up after acute pulmonary embolism: a position paper of the ESC Working Group on Pulmonary Circulation and Right Ventricular Function, in collaboration with the ESC Working Group on Atherosclerosis and Vascular Biology”; endorsed by the European Respiratory Society (ERS)" European Heart Journal 2021 (in press)
  14. Sholzberg M, Tang GT, Rahhal H, AlHamzah M, Baumann Kreuziger L, Ní Áinle F, Alomran F, Alayed K, Alsheef M, AlSumait F, Pompilio CE, Sperlich C, Tangri S, Tang T, Jaksa P, Suryanarayan D, Almarshoodi M, Castellucci L, James PD, Lillicrap D, Carrier M, Beckett A, Colovos C, Jayakar J, Arsenault M-P, Wu C, Doyon K, Andreou R, Dounaevskaia V, Tseng E, Lim G, Fralick M, Middeldorp S, Lee AYY, Zuo F, da Costa BR, Thorpe KE, Negri EM, Cushman M, Jüni P for the RAPID Trial investigators. Heparin for Moderately Ill Patients with Covid-19. medRxiv preprint (opens in a new window)https://doi.org/10.1101/2021.07.08.21259351
  15. Weiss L, Keaney J, Szklanna PB, Prendiville T, Uhrig W, Wynne K, Kelliher S, Ewins K, Comer SP, Egan K, O’Rourke E, Moran E, Petrov G, Patel A, Lennon A, Blanco A, Kevane B, Murphy S, Ní Áinle F*, Maguire PB*. (*Joint corresponding authors). Non-valvular atrial fibrillation patients anticoagulated with rivaroxaban compared with warfarin exhibit reduced circulating extracellular vesicles with attenuated pro-inflammatory protein signatures. J Thromb Haemost. 2021 in press
  16. Sklanna PB, Altaie H, Comer SP, Cullivan S, Kelliher S, Weiss L, Curran J, O’Reilly K, Cotter AG, Marsh B, Gaine S, Mallon P, McCullagh B, Ní Áinle F, Kevane B, Maguire P. Routine haematological parameters may be predictors of COVID-19 severity. Frontiers in Medicine 2021 (Accepted for publication)
  17. Barco S, Valerio L, Galli A, Turatti G, Mahmoudpour SH, Ageno W, Castellucci LA, Cesarman-Maus G, Ddungu H, De Paula EV, Dumantepe M, Goldhaber SZ, Guillermo Esposito MC, Klok FA, Kucher N, McLintock C, Ní Áinle F, Simioni P, Spirk D, Spyropoulos AC, Urano T, Zhai Z, Hunt B, Konstantinides SV. Global reporting of pulmonary embolism-related deaths in the WHO mortality database: vital registration data from 123 countries. Research and Practice in Thrombosis and Haemostasis 2021 doi:10.1002/rth2.12520 ​

2020 

  1. Murphy, C. A., O'Reilly, D. P., Neary, E., El-Khuffash, A., NiAinle, F., McCallion, N., & Maguire, P. B (2020). A review of the role of extracellular vesicles in neonatal physiology and pathology. Pediatric Research. https://doi.org/10.1038/s41390-020-01240-5
  2. Mooney, C., Eogan, M., Ainle, F. N., Cleary, B., Gallagher, J. J., O'Loughlin, J., & Drew, R. J (2020). Predicting bacteraemia in maternity patients using full blood count parameters: A supervised machine learning algorithm approach. International Journal of Laboratory Hematology. https://doi.org/10.1111/ijlh.13434
  3. Skeith, L., Blondon, M., & Ainle, F. N. (2020). Understanding and Preventing Placenta-Mediated Pregnancy Complications. Hamostaseologie, 40(03), 356-363. (opens in a new window)https://doi.org/10.1055/a-1184-8388
  4. Ainle, F. N., & Kevane, B. (2020). Which patients are at high risk of recurrent venous thromboembolism (deep vein thrombosis and pulmonary embolism)? Hematology-American Society of Hematology Education Program (1), 201-212. (opens in a new window)https://doi.org/10.1182/hematology.2020002268
  5. Andrew, L., Ainle, F. N., Blondon, M., Rodger, M. A., & Skeith, L. (2020). Preventing postpartum venous thromboembolism: A call to action to reduce undue maternal morbidity and mortality. Thrombosis Research, 193, 190-197. https://doi.org/10.1016/j.thromres.2020.07.007
  6. Ewins, K., & Ainle, F. N. (2020). VTE risk assessment in pregnancy. Research and Practice in Thrombosis and Haemostasis, 4(2), 183-192. https://doi.org/10.1002/rth2.12290
  7. Gleeson, E. M., Rehill, A. M., Fox, O. W., Ainle, F. N., McDonnell, C. J., Rushe, H. J., McCluskey, S., O'Donnell, J. S., & Preston, R. J. S. (2020). Apolipoprotein A-I enhances activated protein C cytoprotective activity. Blood Advances, 4(11), 2404-2408. https://doi.org/10.1182/bloodadvances.2019001316
  8. Hobohm, L., Keller, K., Valerio, L., Ainle, F. N., Klok, F. A., Munzel, T., Kucher, N., Lankeit, M., Konstantinides, S. V., & Barco, S. (2020). Fatality rates and use of systemic thrombolysis in pregnant women with pulmonary embolism. Esc Heart Failure, 7(5), 2365-2372. https://doi.org/10.1002/ehf2.12775
  9. Kelliher, S., Maguire, P. B., Szklanna, P. B., Weiss, L., Ewins, K., O'Doherty, R., Angelov, D., Ni Ainle, F., & Kevane, B. (2020). Pathophysiology of the Venous Thromboembolism Risk in Preeclampsia. Hamostaseologie, 40(05), 594-604. https://doi.org/10.1055/a-1162-3905
  10. Konstantinides, S. V., Meyer, G., Becattini, C., Bueno, H., Geersing, G. J., Harjola, V. P., Huisman, M. V., Humbert, M., Jennings, C. S., Jimenez, D., Kucher, N., Lang, I. M., Lankeit, M., Lorusso, R., Mazzolai, L., Meneveau, N., Ainle, F. N., Prandoni, P., Pruszczyk, P., Righini, M., Torbicki, A., Van Belle, E., & Zamorano, J. L. (2020). 2019 ESC Guidelines for the dignosis and management of acute pulmonary embolism development Toed in colaboration with the European Respiratory Society (ERS). European Heart Journal, 41(4), 543-603. https://doi.org/10.1093/eurheartj/ehz405
  11. Maguire, P. B., Parsons, M. E., Szklanna, P. B., Zdanyte, M., Munzer, P., Chatterjee, M., Wynne, K., Rath, D., Comer, S. P., Hayden, M., Ainle, F. N., & Gawaz, M. (2020). Comparative Platelet Releasate Proteomic Profiling of Acute Coronary Syndrome versus Stable Coronary Artery Disease. Frontiers in Cardiovascular Medicine, 7, Article 101. https://doi.org/10.3389/fcvm.2020.00101
  12. O'Flaherty, D., Enright, S., Ainle, F. N., & Hayes, N. (2020). Intraoperative cell salvage as part of a blood conservation strategy in an obstetric population with abnormal placentation at a large Irish tertiary referral centre: an observational study. Irish Journal of Medical Science, 189(3), 1053-1060. https://doi.org/10.1007/s11845-020-02182-x
  13. O'Shaughnessy, F., O'Reilly, D., & Ainle, F. N. (2020). Current opinion and emerging trends on the treatment, diagnosis, and prevention of pregnancy-associated venous thromboembolic disease: a review. Translational Research, 225, 20-32. https://doi.org/10.1016/j.trsl.2020.06.004
  14. Rosovsky, R. P., Sanfilippo, K. M., Wang, T. F., Rajan, S. K., Shah, S., Martin, K. A., Ainle, F. N., Huisman, M., Hunt, B. J., Kahn, S. R., Kevane, B., Lee, A. Y. Y., McLintock, C., & Kreuziger, L. B. (2020). Anticoagulation practice patterns in COVID-19: A global survey. Research and Practice in Thrombosis and Haemostasis, 4(6), 969-983. https://doi.org/10.1002/rth2.12414

2019

  1. Szklanna, P. B., Parsons, M. E., Wynne, K., O'Connor, H., Egan, K., Allen, S., Ainle, F. N., & Maguire, P. B. (2019). The Platelet Releasate is Altered in Human Pregnancy. Proteomics Clinical Applications, 13(3), Article 1800162. https://doi.org/10.1002/prca.201800162
  2. Tardy, B., Buchmuller, A., Bistervels, I. M., Ainle, F. N., & Middeldorp, S. (2019). Thromboprophylaxis in pregnant women: For whom and which LMWH dosage? Journal of Thrombosis and Haemostasis, 17(8), 1401-1403. https://doi.org/10.1111/jth.14547
  3. Tardy, B., Chalayer, E., Kamphuisen, P. W., Ainle, F. N., Verhamme, P., Varlet, M. N., Chauleur, C., Rodger, M., Merah, A., Buchmuller, A., Bistervels, I., De Sancho, M. T., Middeldorp, S., Bertoletti, L., & Anticoagulatio, S. S. C. S. C. (2019). Definition of bleeding events in studies evaluating prophylactic antithrombotic therapy in pregnant women: A systematic review and a proposal from the ISTH SSC. Journal of Thrombosis and Haemostasis, 17(11), 1979-1988. https://doi.org/10.1111/jth.14576
  4. Ward, C. M., Andrews, R. K., Wolberg, A., Lip, G. Y. H., Eikelboom, J., De Meyer, S. F., Mast, A., Flick, M., Urano, T., Ny, T., Cutler, D., Ju, L. A., Zhu, C., Randi, A. M., O'Donnell, J. S., O'Brien, S. H., Fijnvandraat, K., Shima, M., Nathwani, A., Luyendyk, J., Vanhoorelbeke, K., Barco, S., Chuansumrit, A., Stanworth, S. J., Curry, N., Del Rio, J. M., Battinelli, E. M., Bos, M. H. A., Reinhardt, C., Peter, K., Gomez, K., Danese, E., Rak, J., Flaumenhaft, R., Di Paola, J., Nilsson, S., Severin, S., Eto, K., Hitchcock, I. S., Ni, H. Y., Despotovic, J., Boilard, E., Rondina, M., Mangin, P., Hamilton, J. R., Suzuki-Inoue, K., Tsukiji, N., Conway, E. M., Maas, C., Emsley, J., Jenne, C. N., Fuchs, T. A., Weitz, J., Johnsen, J. M., Rauova, L., Spyropoulos, A., Goto, S., Verhamme, P., Miranda, S., Rodger, M., Ainle, F., Schreiber, K., Thomas, M., Gal, G., Zentner, D., McLintock, C., Magnusson, M., & Speakers, I. S. A. (2019). Illustrated State-of-the-Art Capsules of the ISTH 2019 Congress in Melbourne, Australia. Research and Practice in Thrombosis and Haemostasis, 3(3), 431-497. https://doi.org/10.1002/rth2.12225
  5. Dillon, A., Egan, K., Kevane, B., Galvin, Z., Maguire, P., Ni Ainle, F., & Stewart, S. (2019). Liver stiffness and thrombin generation in compensated cirrhosis. Research and Practice in Thrombosis and Haemostasis, 3(2), 291-297. https://doi.org/10.1002/rth2.12173
  6. Enright, S., Varadkar, S., Demaio, A., Flynn, C., Ainle, F. N., & Hehir, M. P. (2019). Antecedents of red cell transfusion in a large contemporary obstetric cohort. Journal of Perinatal Medicine, 47(2), 195-199. https://doi.org/10.1515/jpm-2018-0227
  7. Ewins, K., Ainle, F. N., Cheallaigh, C. N., Dunlea, E., Kelliher, S., Imbalzano, E., Bortoluzzi, C., Jou, I., Alfonso-Megido, J., Diaz-Pedroche, M. D., & Monreal, M. (2019). Higher Rates of Death and Major Bleeding Highlight the Inequities That Exist in the Care of People with Venous Thromboembolism Who Experience Social Exclusion: Findings from a Prospective Registry of 79735 Patients (RIETE). Blood, 134. https://doi.org/10.1182/blood-2019-130745
  8. Ewins, K., Ainle, F. N., Dunlea, E., Kelliher, S., Sandys, V., Rooney, H., Macken, L., & Cliona, N. C. (2019). Socially Excluded Persons in Ireland Have an Increased Annual Risk of Hospitalisation Due to Venous Thromboembolic Disease. Blood, 134. https://doi.org/10.1182/blood-2019-130371
  9. Grande, R., Dovizio, M., Marcone, S., Szklanna, P. B., Bruno, A., Ebhardt, H. A., Cassidy, H., Ainle, F. N., Caprodossi, A., Lanuti, P., Marchisio, M., Mingrone, G., Maguire, P. B., & Patrignani, P. (2019). Platelet-Derived Microparticles From Obese Individuals: Characterization of Number, Size, Proteomics, and Crosstalk With Cancer and Endothelial Cells. Frontiers in Pharmacology, 10, Article 7. https://doi.org/10.3389/fphar.2019.00007
  10. Haire, G., Egan, K., Parmar, K., McKinnon, T., Monteith, C., O'Connor, H., Kevane, B., Maguire, P., Szklanna, P. B., Galligan, M., Donnelly, J. C., Allen, S., McCallion, N., Hunt, B., & Ainle, F. N. (2019). Alterations in fibrin formation and fibrinolysis in early onset-preeclampsia: Association with disease severity. European Journal of Obstetrics & Gynecology and Reproductive Biology, 241, 19-23. https://doi.org/10.1016/j.ejogrb.2019.07.035
  11. Hickey, A., Dunlea, E., & Ainle, F. N. (2019). A clinical audit investigating the use of venous thromboembolism (vte) risk assessments in the mater misericordiae university hospital (mmuh) and appropriate prescribing of prophylaxis. Irish Journal of Medical Science, 188, S34-S35.
  12. Kacprzyk, J., Parsons, M., Maguire, P. B., & Stewart, G. S. (2019). Examining gender effects in different types of undergraduate science assessment. Irish Educational Studies, 38(4), 467-480. https://doi.org/10.1080/03323315.2019.1645721
  13. Kelliher, S., Hall, P., Kevane, B., Dinu, D., Ewins, K., MacMahon, P., Ainle, F. N., & Breslin, T. (2019). Implementation of an acute DVT ambulatory care pathway in a large urban centre: current challenges and future opportunities. Thrombosis Journal, 17, Article 14. https://doi.org/10.1186/s12959-019-0203-y
  14. Kelliher, S., Weiss, L., Szklanna, P., Egan, K., Prendiville, T., Moran, E., Petrov, G., Blanco, A., Lennon, A., Murphy, S., Keaney, J., Ainle, F. N., & Maguire, P. (2019). Rivaroxaban Reduces the Levels of Extracellular Vesicles in Patients with Venous Thromboembolism and Non-Valvular Atrial Fibrillation. Blood, 134. https://doi.org/10.1182/blood-2019-126166
  15. Kevane, B., Day, M., Bannon, N., Lawler, L., Breslin, T., Andrews, C., Johnson, H., Fitzpatrick, M., Murphy, K., Mason, O., O'Neill, A., Donohue, F., & Ainle, F. N. (2019). Venous thromboembolism incidence in the Ireland east hospital group: a retrospective 22-month observational study. Bmj Open, 9(6), Article e030059. https://doi.org/10.1136/bmjopen-2019-030059
  16. Miller, I. S., Shiels, L. P., Buckley, G., Connor, K., Byrne, A. T., & Ainle, F. N. (2019). Interrogating the in vivo anti-metastatic action of tinzaparin and simvastatin in an orthotopic surgical resection mouse model of triple negative breast cancer. Cancer Research, 79(13). https://doi.org/10.1158/1538-7445.am2019-2012
  17. O'Brien, K. T., Golla, K., Kranjc, T., O'Donovan, D., Allen, S., Maguire, P., Simpson, J. C., O'Connell, D., Moran, N., & Shields, D. C. (2019). Computational and experimental analysis of bioactive peptide linear motifs in the integrin adhesome. Plos One, 14(1), Article e0210337. https://doi.org/10.1371/journal.pone.0210337
  18. O'Shaughnessy, F., Donnelly, J. C., Bennett, K., Damkier, P., Ainle, F. N., & Cleary, B. J. (2019). Prevalence of postpartum venous thromboembolism risk factors in an Irish urban obstetric population. Journal of Thrombosis and Haemostasis, 17(11), 1875-1885. (opens in a new window)https://doi.org/10.1111/jth.14568

2018

  1. Parsons, M. E. M., Szklanna, P. B., Guerrero, J. A., Wynne, K., Dervin, F., O'Connell, K., Allen, S., Egan, K., Bennett, C., McGuigan, C., Gheveart, C., Ainle, F. N., & Maguire, P. B. (2018). Platelet Releasate Proteome Profiling Reveals a Core Set of Proteins with Low Variance between Healthy Adults. Proteomics, 18(15), Article 1800219. https://doi.org/10.1002/pmic.201800219
  2. Haire, G., Egan, K., Kevane, B., Fay, M., Fortune, A., Savage, R., Doran, E., O'Neill, C., Walsh, K., Kenny, D., Lennon, A., Maguire, P., & Ainle, F. N. (2018). Characterization of Platelet Activation in Patients with Eisenmenger Syndrome. Blood, 132. https://doi.org/10.1182/blood-2018-99-116914
  3. Kevane, B., Allen, S., Walsh, K., Egan, K., Maguire, P. B., Galligan, M. C., Kenny, D., Savage, R., Doran, E., Lennon, A., Neary, E., & Ainle, F. N. (2018). Dual endothelin-1 receptor antagonism attenuates platelet-mediated derangements of blood coagulation in Eisenmenger syndrome. Journal of Thrombosis and Haemostasis, 16(8), 1572-1579. https://doi.org/10.1111/jth.14159
  4. Kevane, B., Day, M., Bannon, N., Lawler, L., Breslin, T., Andrews, C., Johnson, H., Fitzpatrick, M., Murphy, K., Mason, O., Kelliher, S., O'Neill, A., Donohue, F., & Ainle, F. N. (2018). Estimating the Burden of Hospital-Acquired Venous Thromboembolism: The Argument for Implementation of Mandatory Risk Reduction Strategies. Blood, 132. https://doi.org/10.1182/blood-2018-99-112143
  5. Kevane, B., & O'Connell, N. (2018). The current and future role of plasma-derived clotting factor concentrate in the treatment of haemophilia A. Transfusion and Apheresis Science, 57(4), 502-506. https://doi.org/10.1016/j.transci.2018.07.012
  6. Mac Mahon, C., McDonnell, M., Dunne, M., Crowne, M., Crumlish, J., O'Gorman, P., Brannagan, C., Roche, C., Greene, R., Fitzsimon, C., Deegan, C., Browne, J., Davenport, K., Coveney, S., Fortune, A., Ainle, F. N., Fay, M., Breslin, T., & Murphy, S. (2018). ANTICOAGULANT ASSOCIATED INTRACEREBRAL HAEMORRHAGE - A PROTOCOL TO REDUCE TIME TO TREATMENT. Age and Ageing, 47. https://doi.org/10.1093/ageing/afy140.111
  7. Maguire, P., Szklanna, P., Parsons, M., Wynne, K., O'Connor, H., O'Connell, K., Egan, K., McGuigan, C., Rickard, S., & Ainle, F. N. (2018). The Hundred-Person Platelet Releasate Project (100PREPs): A Barcode for Human Health and Disease. Blood, 132. https://doi.org/10.1182/blood-2018-99-115421
  8. Maguire, P. B., Donlon, T., Parsons, M., Wynne, K., Dillon, E., Ni Ainle, F., & Szklanna, P. B. (2018). Proteomic Analysis Reveals a Strong Association of beta-Catenin With Cadherin Adherens Junctions in Resting Human Platelets. Proteomics, 18(9), Article 1700419. https://doi.org/10.1002/pmic.201700419
  9. Monteith, C., Egan, K., O'Connor, H., Maguire, P., Kevane, B., Szklanna, P. B., Cooley, S., Malone, F., & Ainle, F. N. (2018). Early onset preeclampsia is associated with an elevated mean platelet volume (MPV) and a greater rise in MPV from time of booking compared with pregnant controls: results of the CAPE study. Journal of Perinatal Medicine, 46(9), 1010-1015. https://doi.org/10.1515/jpm-2017-0188
  10. O'Reilly, D., Egan, K., Burke, O., Griffiths, A., Neary, E., Blanco, A., Szklanna, P., Maguire, P., McCallion, N., & Ainle, F. N. (2018). The Population of Circulating Extracellular Vesicles Dramatically Alters after Very Premature Delivery-a Previously Unrecognised Postnatal Adaptation Process? Blood, 132. https://doi.org/10.1182/blood-2018-99-113180
  11. O'Shaughnessy, F., Donnelly, J., Cooley, S., Bennett, K., Ainle, F. N., & Cleary, B. (2018). Initiating postpartum pharmacological thromboprophylaxis: A comparison of international recommendations. American Journal of Obstetrics and Gynecology, 218(1), S493-S494.

2017 

  1. O'Shaughnessy, F., Donnelly, J. C., Cooley, S. M., Deering, M., Raman, A., Gannon, G., Hickey, J., Holland, A., Hayes, N., Bennett, K., Ainle, F. N., & Cleary, B. J. (2017). Thrombocalc: implementation and uptake of personalized postpartum venous thromboembolism risk assessment in a high-throughput obstetric environment. Acta Obstetricia Et Gynecologica Scandinavica, 96(11), 1382-1390. https://doi.org/10.1111/aogs.13206
  2. Parsons, M. E. M., McParland, D., Szklanna, P. B., Guang, M. H. Z., O'Connell, K., O'Connor, H. D., McGuigan, C., Ainle, F. N., McCann, A., & Maguire, P. B. (2017). A Protocol for Improved Precision and Increased Confidence in Nanoparticle Tracking Analysis Concentration Measurements between 50 and 120 nm in Biological Fluids. Frontiers in Cardiovascular Medicine, 4, Article 68. https://doi.org/10.3389/fcvm.2017.00068
  3. Parsons, M.E., O’Connell, K., Allen, S., Egan, K., Szklanna, P.B., McGuigan, C., Áinle F.N., Maguire, P.B. Thrombin generation correlates with disease duration in multiple sclerosis (MS): novel insights into the MS-associated prothrombotic state (2017). Mult Scler J Exp Transl Clin. 26;3(4):2055217317747624. doi: 10.1177/2055217317747624.
  4. Szklanna, P. B., Wynne, K., Nolan, M., Egan, K., Ni Ainle, F., & Maguire, P. B. (2017). Comparative proteomic analysis of trophoblast cell models reveals their differential phenotypes, potential uses, and limitations. Proteomics, 17(10), Article 1700037. https://doi.org/10.1002/pmic.201700037
  5. Vajen, T., Benedikter, B. J., Heinzmann, A. C. A., Vasina, E. M., Henskens, Y., Parsons, M., Maguire, P. B., Stassen, F. R., Heemskerk, J. W. M., Schurgers, L. J., & Koenen, R. R. (2017). Platelet extracellular vesicles induce a pro-inflammatory smooth muscle cell phenotype. Journal of Extracellular Vesicles, 6, Article 1322454. https://doi.org/10.1080/20013078.2017.1322454
  6. Angelov, D., Egan, K., & Ainle, F. N. (2017). CHARACTERIZATION OF PLATELET ACTIVATION MARKERS IN EARLY ONSET PREECLAMPSIA. Haematologica, 102, 592-593.
  7. Barrett, A., Kevane, B., Hall, P., Ainle, F. N., & Breslin, T. (2017). Screening for Malignancy in Patients With Unprovoked Venous Thromboembolism: A Single-Center Retrospective Case Series. Clinical and Applied Thrombosis-Hemostasis, 23(7), 735-739. https://doi.org/10.1177/1076029616659694
  8. Bistervels, I., Buchmuller, A., Bleker, S., Chauleur, C., Ainle, F. N., Donnelly, J., Verhamme, P., Jacobsen, A. F., Decousus, H., Middeldorp, S., & Highlow, I. (2017). Neuraxial anesthesia in pregnant women using thrombosis prophylaxis: data from the Highlow study. Thrombosis Research, 151, S131-S132.
  9. Egan, K., Dillon, A., Dunne, E., Kevane, B., Galvin, Z., Maguire, P., Kenny, D., Stewart, S., & Ainle, F. N. (2017). Increased soluble GPVI levels in cirrhosis: evidence for early in vivo platelet activation. Journal of Thrombosis and Thrombolysis, 43(1), 54-59. https://doi.org/10.1007/s11239-016-1401-0
  10. Egan, K., O'Connor, H., Kevane, B., Malone, F., Lennon, A., Al Zadjali, A., Cooley, S., Monteith, C., Maguire, P., Szklanna, P. B., Allen, S., McCallion, N., & Ni Ainle, F. (2017). Elevated plasma TFPI activity causes attenuated TF-dependent thrombin generation in early onset preeclampsia. Thrombosis and Haemostasis, 117(8), 1549-1557. https://doi.org/10.1160/th16-12-0949
  11. Egan, K., van Geffen, J. P., Ma, H., Kevane, B., Lennon, A., Allen, S., Neary, E., Parsons, M., Maguire, P., Wynne, K., Kennedy, R. O., Heemskerk, J. M., & Ainle, F. N. (2017). Effect of platelet-derived beta-thromboglobulins on coagulation. Thrombosis Research, 154, 7-15. https://doi.org/10.1016/j.thromres.2017.03.023
  12. Kevane, B., & Ainle, F. N. (2017). Contraception and menstrual bleeding during venous thromboembolism treatment: Does current practice reflect expert option? Thrombosis Research, 153, 121-122. https://doi.org/10.1016/j.thromres.2017.04.013
  13. Kevane, B., Egan, K., Allen, S., Maguire, P., Neary, E., Lennon, A., & Ni Ainle, F. (2017). Endothelial barrier protective properties of low molecular weight heparin: A novel potential tool in the prevention of cancer metastasis? Research and Practice in Thrombosis and Haemostasis, 1(1), 23-32. https://doi.org/10.1002/rth2.12011
  14. McDonnell, B. P., Glennon, K., McTiernan, A., O'Connor, H. D., Kirkham, C., Kevane, B., Donnelly, J. C., & Ni Ainle, F. (2017). Adjustment of therapeutic LMWH to achieve specific target anti-FXa activity does not affect outcomes in pregnant patients with venous thromboembolism. Journal of Thrombosis and Thrombolysis, 43(1), 105-111. (opens in a new window)https://doi.org/10.1007/s11239-016-1409-5

2016

  1. O'Connor, H. D., Egan, K., Kevane, B., Malone, F. D., Cooley, S. M., Geary, M., Maguire, P. B., Szklanna, P., Tully, E. C., Neary, E., O'Loughlin, J., Allen, S., McCallion, N., & Ainle, F. N. (2016). Coagulation balance in early onset preeclampsia (EOP). American Journal of Obstetrics and Gynecology, 214(1), S408-S408. https://doi.org/10.1016/j.ajog.2015.10.829
  2. Szklanna, P. B., Foy, M., Wynne, K., Byrne, D., & Maguire, P. B. (2016). Analysis of the proteins associated with platelet detergent resistant membranes. Proteomics, 16(17), 2345-2350. https://doi.org/10.1002/pmic.201500309
  3. Bleker, S. M., Buchmuller, A., Chauleur, C., Ainle, F. N., Donnelly, J., Verhamme, P., Jacobsen, A. F., Ganzevoort, W., Prins, M., Beyer-Westendorf, J., DeSancho, M., Konstantinides, S., Pabinger, I., Rodger, M., Decousus, H., & Middeldorp, S. (2016). Low-molecular-weight heparin to prevent recurrent venous thromboembolism in pregnancy: Rationale and design of the High-low study, a randomised trial of two doses. Thrombosis Research, 144, 62-68. https://doi.org/10.1016/j.thromres.2016.06.001
  4. Bleker, S. M., Ingrid, B. M., Buchmuller, A., Chauleur, C., Ainle, F. N., Donnelly, J., Verhamme, P., Jacobsen, A. F., Decousus, H., & Middeldorp, S. (2016). Interm Report of the Highlow Study: A Randomized Controlled Trial Comparing Two Doses of Low Molecular Weight Heparin for the Prevention of Pregnancy-Associated Recurrent Venous Thromboembolism. Blood, 128(22). https://doi.org/10.1182/blood.V128.22.1444.1444
  5. Crowley, M. P., Kevane, B., O'Shea, S. I., Quinn, S., Egan, K., Gilligan, O. M., & Ainle, F. N. (2016). Plasma Thrombin Generation and Sensitivity to Activated Protein C Among Patients With Myeloma and Monoclonal Gammopathy of Undetermined Significance. Clinical and Applied Thrombosis-Hemostasis, 22(6), 554-562. https://doi.org/10.1177/1076029615625825
  6. Crowley, M. P., O'Neill, S. B., Kevane, B., O'Neill, D. C., Eustace, J. A., Cahill, M. R., Bird, B., Maher, M. M., O'Regan, K., & O'Shea, D. (2016). Ionizing radiation exposure as a result of diagnostic imaging in patients with lymphoma. Clinical & Translational Oncology, 18(5), 533-536. https://doi.org/10.1007/s12094-015-1394-8
  7. Egan, K., O'Connor, H., Kevane, B., Malone, F., Al Zadjali, A., Cooley, S., Monteith, C., Maguire, P., Szklanna, P., Allen, S., McCallion, N., & Ainle, F. N. (2016). Tissue Factor Pathway Inhibitor Mediates Attenuation of Tissue Factor-Stimulated Thrombin Generation in Early Onset Preeclampsia. Blood, 128(22). https://doi.org/10.1182/blood.V128.22.1431.1431
  8. Enright, S., Ainle, F. N., & Foran, A. (2016). Audit of Red Cell Transfusions in the Neonatal Intensive Care Unit, Rotunda Hospital 2011-2015. Blood, 128(22).
  9. Husarova, V., Donnelly, G., Doolan, A., Garstka, M., Ainle, F. N., & MeCaul, C. (2016). Preferences of Jehovah's Witnesses regarding haematological supports in an obstetric setting: experience of a single university teaching hospital. International Journal of Obstetric Anesthesia, 25, 53-57. https://doi.org/10.1016/j.ijoa.2015.09.005
  10. Kevane, B., Allen, S., Walsh, K., Egan, K., Maguire, P., Kenny, D., Crawford, S., Lennon, A., Savage, R., Doran, E., Neary, E., & Ainle, F. N. (2016). A Novel Beneficial Role for Macitentan in Patients at High Thrombosis Risk: Attenuation of Platelet-Mediated Derangements of Blood Coagulation in Eisenmenger Syndrome. Blood, 128(22). https://doi.org/10.1182/blood.V128.22.2602.2602
  11. Kevane, B., Egan, K., Allen, S., Maguire, P., Neary, E., Lennon, A., & Ainle, F. N. (2016). Endothelial Protective Properties of Low Molecular Weight Heparin (LMWH) Tinzaparin in Combination with Statin: A Novel Potential Therapeutic Tool in Preventing Cancer Metastasis? Blood, 128(22). (opens in a new window)https://doi.org/10.1182/blood.V128.22.881.881

2015

  1. Kevane, B., McKenna, P., Walsh, K., Donnelly, J. C., Flood, K., Cullen, M., Bowen, M., Thornton, P., Loughrey, J., Coulter-Smith, S., & Ni Ainle, F. (2015). Haemorrhagic and thrombotic complications in pregnant women with acquired and congenital cardiac disease. Journal of Perinatal Medicine, 43(2), 165-169. https://doi.org/10.1515/jpm-2014-0088
  2. Neary, E., McCallion, N., Kevane, B., Cotter, M., Egan, K., Regan, I., Kirkham, C., Mooney, C., Coulter-Smith, S., & Ni Ainle, F. (2015). Coagulation indices in very preterm infants from cord blood and postnatal samples. Journal of Thrombosis and Haemostasis, 13(11), 2021-2030. https://doi.org/10.1111/jth.13130
  3. Egan, K., Dillon, A., Galvin, Z., Kevane, B., Neary, E., Stewart, S., & Ainle, F. N. (2015). Thrombin generation varies with fibrosis score in patients with well-compensated liver cirrhosis of mixed aetiology. Journal of Thrombosis and Haemostasis, 13, 178-179.
  4. Egan, K., Dunne, E., Dillon, A., Kevane, B., Galvin, Z., Kenny, D., Stewart, S., & Ni Ainie, F. (2015). Increased Soluble GPVI Levels in Cirrhosis: Evidence for Collagen Induced Platelet Activation In Vivo. Blood, 126(23).
  5. Egan, K., Kevane, B., & Ainle, F. N. (2015). Elevated venous thromboembolism risk in preeclampsia: molecular mechanisms and clinical impact. Biochemical Society Transactions, 43, 696-701. https://doi.org/10.1042/bst20140310
  6. Egan, K., Ma, H., Kevane, B., Lennon, A., Neary, E., Wynne, K., Allen, S., O'Shea, S., Kennedy, R. O., & Ni Ainle, F. (2015). Platelet-Derived Beta Thromboglobulin: A Potential Novel Activator of Coagulation Factor X. Blood, 126(23).
  7. Feighery, R., Maguire, P., Ryan, M. R., & McMorrow, T. (2008). A proteomic approach to immune-madiated epithelial-mesenchymal transition. Proteomics Clinical Applications, 2(7-8), 1110-1117. https://doi.org/10.1002/prca.200780148
  8. Fogarty, H., Kevane, B., & Fortune, A. (2015). NK/T Cell Lymphoma Presenting with Visual Loss. Irish Journal of Medical Science, 184, 434-435.

2014

  1. Gleeson, E. M., O'Donnell, J. S., Hams, E., Ainle, F. N., Kenny, B. A., Fallon, P. G., & Preston, R. J. S. (2014). Activated factor X signaling via protease-activated receptor 2 suppresses pro-inflammatory cytokine production from lipopolysaccharide-stimulated myeloid cells. Haematologica, 99(1), 185-193. https://doi.org/10.3324/haematol.2013.086918
  2. Kevane, B., Crowley, M. P., Bolster, M., & Gilligan, O. (2014). Myeloma Relapse Involving the Heart and Presenting As Acute Cardiac Failure. Journal of Clinical Oncology, 32(18), E67-E68. https://doi.org/10.1200/jco.2012.47.6713
  3. Kevane, B., Donnelly, J., D'Alton, M., Cooley, S., Preston, R. J. S., & Ainle, F. N. (2014). Risk factors for pregnancy-associated venous thromboembolism: a review. Journal of Perinatal Medicine, 42(4), 417-425. https://doi.org/10.1515/jpm-2013-0207
  4. Kevane, B., Dowd, A., Lennon, A., Bacon, C. L., & Fortune, A. (2014). Splenectomy-Related Red Cell Lysis Resistance Causing Analytical Difficulty in a Patient with a Hematological Malignancy. Clinical Laboratory, 60(11), 1925-1928. https://doi.org/10.7754/Clin.Lab.2014.140308
  5. Kevane, B., McKenna, P., Walsh, K., Donnelly, J. C., Flood, K., Cullen, M., Bowen, M., Thornton, P., Loughrey, J., & Ainle, F. N. (2014). HAEMATOLOGICAL MORBIDITY IN OBSTETRIC PATIENTS WITH CARDIAC DISEASE. Haematologica, 99, 479-479.
  6. Kevane, B., O' Connor, H., Cooley, S., Egan, K., Flood, K., & Ainle, F. N. (2014). THE EFFECT OF MORBID OBESITY ON THROMBIN GENERATION AND SENSITIVITY TO THE ANTICOAGULANT ACTIVATED PROTEIN C IN PREGNANT WOMEN. Haematologica, 99, 475-475.
  7. Langabeer, S. E., Haslam, K., Linders, J., Percy, M. J., Conneally, E., Hayat, A., Hennessy, B., Leahy, M., Murphy, K., Murray, M., Ainle, F. N., Thornton, P., & Sargent, J. (2014). Molecular heterogeneity of familial myeloproliferative neoplasms revealed by analysis of the commonly acquired JAK2, CALR and MPL mutations. Familial Cancer, 13(4), 659-663. https://doi.org/10.1007/s10689-014-9743-2
  8. Langabeer, S. E., Linders, J., Conneally, E., Hayat, A., Hennessy, B., Leahy, M., Murphy, K., Murray, M., Ainle, F. N., Thornton, P., & Sarjent, J. (2014). Genotypic and phenotypic heterogeneity of familial myeloproliferative neoplasms. British Journal of Haematology, 165, 15-15.
  9. Monteith, C., Ainle, F. N., Cooley, S., Lambert, J. S., Kelleher, B., Jackson, V., & Eogan, M. (2014). Hepatitis C virus-associated thrombocytopenia in pregnancy: impact upon multidisciplinary care provision. Journal of Perinatal Medicine, 42(1), 135-138. https://doi.org/10.1515/jpm-2013-0080
  10. Neary, E., Ainle, F. N., Cotter, M., & McCallion, N. (2014). Coagulation values in extreme premature infants. Transfusion, 54(8), 2134-2134. https://doi.org/10.1111/trf.12734
  11. Neary, E., McCallion, N., Kevane, B., Cotter, M., Egan, K., Irene, R., & Ni Ainle, F. (2014). To Characterize Standard Laboratory Coagulation Parameters and Plasma Thrombin Generation in Very Preterm Infants and to Investigate Their Relationship to Clinical Outcomes. Blood, 124(21).
  12. Scully, M., Thomas, M., Underwood, M., Watson, H., Langley, K., Camilleri, R. S., Clark, A., Creagh, D., Rayment, R., McDonald, V., Roy, A., Evans, G., McGuckin, S., Ainle, F. N., Maclean, R., Lester, W., Nash, M., Scott, R., Brien, P. O., & Collaborators, U. K. T. T. P. R. (2014). Thrombotic thrombocytopenic purpura and pregnancy: presentation, management, and subsequent pregnancy outcomes. Blood, 124(2), 211-219. https://doi.org/10.1182/blood-2014-02-553131
  13. Corcoran, D., Murphy, D., Donnelly, J. C., & Ainle, F. N. (2014). The prevalence of maternal F cells in a pregnant population and potential overestimation of foeto-maternal haemorrhage as a consequence. Blood Transfusion, 12(4), 570-574. https://doi.org/10.2450/2014.0297-13
  14. Crowley, M. P., Kevane, B., O'Shea, S. I., Eustace, J. A., Quinn, S., Egan, K., Gilligan, O. M., & Ainle, F. N. (2014). PATTERNS OF DIFFERING THROMBIN GENERATION AND SENSITIVITY TO THE ANTICOAGULANT ACTIVATED PROTEIN C IN PATIENTS WITH MYELOMA AND MONOCLONAL GAMMOPATHY OF UNDETERMINED SIGNIFICANCE. Haematologica, 99, 478-478.
  15. Dempsey, E., Dervin, F., & Maguire, P. B. (2014). Platelet Derived Exosomes Are Enriched for Specific microRNAs Which Regulate WNT Signalling in Endothelial Cells. Blood, 124(21). https://doi.org/10.1182/blood.V124.21.2760.2760
  16. Dervin, F., Wynne, K., & Maguire, P. B. (2014). Human Platelet Exosome Proteomics Leads to the Identification of WNT Positive Exosomes Which Impact Canonical WNT Signalling in Target Cells. Blood, 124(21).
  17. Donnellan, E., Kevane, B., Bird, B. R. H., & Ainle, F. N. (2014). Cancer and venous thromboembolic disease: from molecular mechanisms to clinical management. Current Oncology, 21(3), 134-143. https://doi.org/10.3747/co.21.1864
  18. Donnelly, J. C., Cooley, S. M., Doyle, A., Murphy, D., Corcoran, D., Kumpel, B., & Ainle, F. N. (2014). False positive Kleihauer-Betke (acid elution) test caused by elevated maternal fetal haemoglobin F cells. European Journal of Obstetrics & Gynecology and Reproductive Biology, 172, 136-137. https://doi.org/10.1016/j.ejogrb.2013.10.012

2013

  1. Iglesias, J., MacMahon, P., Fay, M., Ainle, F. N., O'Gorman, P., Bacon, L., & Fortune, A. (2013). INCIDENCE OF PICC LINE-ASSOCIATED VENOUS THROMBOSIS IN HAEMATOLOGY PATIENTS AT THE MATER MISERICORDIAE UNIVERSITY HOSPITAL. Irish Journal of Medical Science, 182, S497-S497.
  2. Kevane, B., Crowley, M., Bowler, A., Mohamad, M., Gilligan, O., & Cassidy, E. (2013). PSYCHOLOGICAL MORBIDITY FOLLOWING THE DIAGNOSIS OF A HAEMATOLOGICAL MALIGNANCY. Haematologica, 98, 451-451.
  3. Macaulay, I. C., Thon, J. N., Tijssen, M. R., Steele, B. M., MacDonald, B. T., Meade, G., Burns, P., Rendon, A., Salunkhe, V., Murphy, R. P., Bennett, C., Watkins, N. A., He, X., Fitzgerald, D. J., Italiano, J. E., & Maguire, P. B. (2013). Canonical Wnt signaling in megakaryocytes regulates proplatelet formation. Blood, 121(1), 188-196. https://doi.org/10.1182/blood-2012-03-416875
  4. Crowley, M. P., Kevane, B. M., Eustace, J. A., O'Shea, S., & Gilligan, O. M. (2013). Thromboprophylaxis In Myeloma: A National Survey. Blood, 122(21). (opens in a new window)https://doi.org/10.1182/blood.V122.21.1694.1694

2012

  1. Crowley, M., & Kevane, B. (2012). THE D DIMER TEST IN THE DIAGNOSIS OF VENOUS THROMBOEMBOLISM - AN AUDIT OF IT'S UTILIZATION IN AN IRISH TEACHING HOSPITAL AND A SURVEY OF JUNIOR DOCTOR KNOWLEDGE OF IT'S USES AND LIMITATIONS. Haematologica, 97, 422-422.
  2. Steele, B. M., Harper, M. T., Smolenski, A. P., Alkazemi, N., Poole, A. W., Fitzgerald, D. J., & Maguire, P. B. (2012). WNT-3a modulates platelet function by regulating small GTPase activity. Febs Letters, 586(16), 2267-2272. (opens in a new window)https://doi.org/10.1016/j.febslet.2012.05.060

2011

  1. Gleeson, E. M., Ainle, F. N., Kenny, B., O'Donnell, J. S., & Preston, R. J. S. (2011a). ACTIVATED COAGULATION FACTOR X IS A NOVEL REGULATOR OF MONOCYTE APOPTOTIC AND INFLAMMATORY SIGNALING. Irish Journal of Medical Science, 180, S294-S294.
  2. Gleeson, E. M., Ainle, F. N., Kenny, B. A., O'Donnell, J. S., & Preston, R. J. S. (2011b). Activated factor X is a novel regulator of monocyte toll-like receptor signaling. Journal of Thrombosis and Haemostasis, 9, 757-757.
  3. Johnston, O., Cassidy, H., O'Connell, S., O'Riordan, A., Gallagher, W., Maguire, P. B., Wynne, K., Cagney, G., Ryan, M. P., Conlon, P. J., & McMorrow, T. (2011). Identification of beta 2-microglobulin as a urinary biomarker for chronic allograft nephropathy using proteomic methods. Proteomics Clinical Applications, 5(7-8), 422-431. https://doi.org/10.1002/prca.201000160
  4. Maguire, P. B., Steele, B. M., & Fitzgerald, D. J. (2011). Novel Platelet Signalling Pathways Identified via Proteomics. Current Proteomics, 8(3), 208-215.
  5. Salunkhe, V. A., Macaulay, I., Nuernberg, S., McCarthy, C., Ouwehand, W. H., Fitzgerald, D. J., & Maguire, P. (2011). The MEIS1 Interactome in Megakaryocytes Reveals a Role in Cell Cycle Regulation. Blood, 118(21), 1449-1450.
  6. Ainle, F. N., Johnson, J. A., Gleeson, E. M., Kenny, B. A., O'Donnell, J. S., & Preston, R. J. S. (2011). High-density lipoprotein enhances activated protein C cytoprotective signaling on endothelial cells. Journal of Thrombosis and Haemostasis, 9, 740-741.
  7. Ainle, F. N., O'Donnell, J. S., Johnson, J. A., Brown, L., Gleeson, E. M., Smith, O. P., & Preston, R. J. S. (2011). Activated Protein C N-Linked Glycans Modulate Cytoprotective Signaling Function on Endothelial Cells. Journal of Biological Chemistry, 286(2), 1323-1330. (opens in a new window)https://doi.org/10.1074/jbc.M110.159475

2010

  1. Goodall, A. H., Burns, P., Salles, I., Macaulay, I. C., Jones, C. I., Ardissino, D., de Bono, B., Bray, S. L., Deckmyn, H., Dudbridge, F., Fitzgerald, D. J., Garner, S. F., Gusnanto, A., Koch, K., Langford, C., O'Connor, M. N., Rice, C. M., Stemple, D., Stephens, J., Trip, M. D., Zwaginga, J. J., Samani, N. J., Watkins, N. A., Maguire, P. B., Ouwehand, W. H., & Bloodomics, C. (2010). Transcription profiling in human platelets reveals LRRFIP1 as a novel protein regulating platelet function. Blood, 116(22), 4646-4656. https://doi.org/10.1182/blood-2010-04-280925
  2. Mulvihill, M. M., Kevane, B., Otway, G., & O'Shea, S. I. (2010). Audit of vitamin K therapy for reversal of excessive anticoagulation. British Journal of Haematology, 149, 41-41.
  3. Whately, K., Lysaght, J., Ainle, F. N., Pidgeon, G. P., Preston, R. J. S., Kay, E., O'Donnell, J. S., & Reynolds, J. V. (2010). Tumour cell expression of protein C pathway receptors can mediate the interplay between coagulation proteases and malignancy. British Journal of Surgery, 97, 25-25.

2009

  1. Ainle, F. N., Preston, R. J. S., Jenkins, P. V., Nel, H. J., Johnson, J. A., Smith, O. P., White, B., Fallon, P. G., & O'Donnell, J. S. (2009). Protamine sulfate down-regulates thrombin generation by inhibiting factor V activation. Blood, 114(8), 1658-1665. https://doi.org/10.1182/blood-2009-05-222109
  2. Bernimoulin, M., Waters, E. K., Foy, M., Steele, B. M., Sullivan, M., Falet, H., Walsh, M. T., Barteneva, N., Geng, J. G., Hartwig, J. H., Maguire, P. B., & Wagner, D. D. (2009). Differential stimulation of monocytic cells results in distinct populations of microparticles. Journal of Thrombosis and Haemostasis, 7(6), 1019-1028. https://doi.org/10.1111/j.1538-7836.2009.03434.x
  3. Preston, R. J. S., Tran, S., Johnson, J. A., Ainle, F. N., Harmon, S., White, B., Smith, O. P., Jenkins, P. V., Dahlback, B., & O'Donnell, J. S. (2009). Platelet Factor 4 Impairs the Anticoagulant Activity of Activated Protein C. Journal of Biological Chemistry, 284(9), 5869-5875. https://doi.org/10.1074/jbc.M804703200
  4. Steele, B. M., Harper, M. T., Macaulay, I. C., Morrell, C. N., Perez-Tamayo, A., Foy, M., Habas, R., Poole, A. W., Fitzgerald, D. J., & Maguire, P. B. (2009). Canonical Wnt signaling negatively regulates platelet function. Proceedings of the National Academy of Sciences of the United States of America, 106(47), 19836-19841. (opens in a new window)https://doi.org/10.1073/pnas.0906268106

2008

  1. Preston, R. J. S., Johnson, J. A., Ainle, F. N., Harmon, S., Smith, O. P., White, B., & O'Donnell, J. S. (2008). Platelet Factor 4 Mediates Activated Protein C Resistance by Impairment of Protein S Cofactor Enhancement. Blood, 112(11), 13-14.
  2. Waters, E. K., Bernimoulin, M., Foy, M., Steele, B. M., Sullivan, M., Falet, H., Hartwig, J. H., Maguire, P. B., & Wagner, D. D. (2008). Differential Stimulation of Monocytic Cells Results in Distinct Populations of Microparticles. Blood, 112(11), 456-456.
  3. Ainle, F. N., Hamnvik, O. P. R., Gulmann, C., Bermingham, C., Kelly, J., Mc Evoy, P., & Murphy, P. (2008). Diffuse large B-cell lymphoma with isolated bone marrow involvement presenting with secondary cold agglutinin disease. International Journal of Laboratory Hematology, 30(5), 444-445. https://doi.org/10.1111/j.1751-553X.2007.00977.x
  4. Ainle, F. N., Mumford, A., Tallon, E., McCarthy, D., & Murphy, K. (2008). A vitamin K epoxide reductase complex subunit 1 mutation in an Irish patient with warfarin resistance. Irish Journal of Medical Science, 177(2), 159-161. https://doi.org/10.1007/s11845-008-0126-2
  5. Ainle, F. N., Preston, R. J. S., Jenkins, V. P., Johnson, J. A., Harmon, S., Smith, O., White, B., & O'Donnell, J. S. (2008). Enhancement of the Anticoagulant Properties of Protamine Sulphate by Activated Protein C. Blood, 112(11), 14-15.
  6. Ainle, F. N., Wong, A., Appleby, N., Byrne, B., Regan, C., Hassan, T., Milner, M., Sullivan, A. O., White, B., & O'Donnell, J. (2008). Efficacy and safety of once daily low molecular weight heparin (tinzaparin sodium) in high risk pregnancy. Blood Coagulation & Fibrinolysis, 19(7), 689-692. https://doi.org/10.1097/MBC.0b013e32830b14ef
  7. Atzei, P., Maguire, P. B., Kennedy, B. N., & Moynagh, P. N. (2008). Cactin, a novel regulator of TLR signalling pathways. Journal of Neuroimmunology, 197(2), 162-162.
  8. Harmon, S., Preston, R. J. S., Ainle, F. N., Johnson, J. A., Cunningham, M. S., Smith, O. P., White, B., & O'Donnell, J. S. (2008). Dissociation of Activated Protein C Functions by Elimination of Protein S Cofactor Enhancement. Journal of Biological Chemistry, 283(45), 30531-30539. https://doi.org/10.1074/jbc.M802338200
  9. Johnson, J., Ainle, F. N., Harmon, S., O'Donnell, J. S., & Preston, R. J. S. (2008). A Single Amino Acid Substitution (I18V) in the Gla Domain of Activated Protein C Markedly Impairs Ability of PE and GlyCer to Enhance Anticoagulant Activity. Blood, 112(11), 1055-1055.
  10. Murphy, C., Crotty, F., Smyth, E. C., Healy, G., Breathnach, O. S., Grogan, L., Ainle, F. N., & Murphy, P. (2008). Alterations in serum prothrombotic markers induced by treatment with bevacizumab-based chemotherapy regimens. Journal of Clinical Oncology, 26(15). https://doi.org/10.1200/jco.2008.26.15_suppl.15034
  11. O'Riordan, A., Johnston, O., McMorrow, T., Wynne, K., Maguire, P., Hegarty, J. E., McCormick, A., Watson, A. J., Cagney, G., Gallagher, W. M., & Ryan, M. R. (2008). Identification of Apolipoprotein AI as a serum biomarker of chronic kidney disease in liver transplant recipients, using proteomic techniques. Proteomics Clinical Applications, 2(9), 1338-1348. (opens in a new window)https://doi.org/10.1002/prca.200780167

2007

  1.  
  2. Behan, A. T., Foy, M., Wynne, K., Clarke, M., Sullivan, M., Cotter, D. R., & Maguire, P. B. (2007). Analysis of membrane microdomain-associated proteins in the insular cortex of post-mortem human brain. Proteomics Clinical Applications, 1(10), 1324-1331. https://doi.org/10.1002/prca.200700047
  3. Coppinger, J. A., & Maguire, P. B. (2007). Insights into the platelet releasate. Current Pharmaceutical Design, 13(26), 2640-2646. https://doi.org/10.2174/138161207781662885
  4. Coppinger, J. A., O'Connor, R., Wynne, K., Flanagan, M., Sullivan, M., Maguire, P. B., Fitzgerald, D. J., & Cagney, G. (2007). Moderation of the platelet releasate response by aspirin. Blood, 109(11), 4786-4792. https://doi.org/10.1182/blood-2006-07-038539
  5. Costello, D., Tharmabala, M., Ainle, F. N., Spooner, M., Appleby, N., & Murphy, P. (2007). Risk factors and sequelae of cerebral vein thrombosis: A five year retrospective audit. Haematologica-the Hematology Journal, 92, 305-305.
  6. Foy, M., & Maguire, P. B. (2007). Recent advances in the characterisation of the platelet membrane system by proteomics. Current Pharmaceutical Design, 13(26), 2647-2655. https://doi.org/10.2174/138161207781662911
  7. Kerrigan, S. W., Jakubovics, N. S., Keane, C., Maguire, P., Wynne, K., Jenkinson, H. F., & Cox, D. (2007). Role of streptococcus gordonii surface proteins SspA/SspB and hsa in platelet function. Infection and Immunity, 75(12), 5740-5747. https://doi.org/10.1128/iai.00909-07
  8. Langabeer, S. E., Ainle, F. N., Conneally, E., & Lawler, M. (2007). Incidence and significance of the JAK2 V617F mutation in patients with chronic myeloproliferative disorders. Irish Journal of Medical Science, 176(2), 105-109. (opens in a new window)https://doi.org/10.1007/s11845-007-0026-x

2006

  1. Ainle, F. N., Hayden, P. J., Crosby, P., Murphy, K., McCarthy, D., Kelly, J., & Neat, M. J. (2006). Concurrent rearrangement of BCL1 and BCL6 with a single immunoglobulin locus in a case of diffuse large B-cell lymphoma. Leukemia & Lymphoma, 47(12), 2655-2656. https://doi.org/10.1080/10428190600909586
  2.  

2005

  1. Kelly, P., Maguire, P. B., Bennett, M., Fitzgerald, D. J., Edwards, R. J., Thiede, B., Treumann, A., Collins, J. K., O'Sullivan, G. C., Shanahan, F., & Dunne, C. (2005). Correlation of probiotic Lactobacillus salivarius growth phase with its cell wall-associated proteorne. Fems Microbiology Letters, 252(1), 153-159. (opens in a new window)https://doi.org/10.1016/j.femsle.2005.08.051

2004

  1. McRedmond, J. P., Park, S. D., Reilly, D. F., Coppinger, J. A., Maguire, P. B., Shields, D. C., & Fitzgerald, D. J. (2004). Integration of proteomics and genomics in platelets - A profile of platelet proteins and platelet-specific genes. Molecular & Cellular Proteomics, 3(2), 133-144. https://doi.org/10.1074/mcp.M300063-MCP200
  2. Coppinger, J. A., Cagney, G., Toomey, S., Kislinger, T., Belton, O., McRedmond, J. P., Cahill, D. J., Emili, A., Fitzgerald, D. J., & Maguire, P. B. (2004). Characterization of the proteins released from activated platelets leads to localization of novel platelet proteins in human atherosclerotic lesions. Blood, 103(6), 2096-2104. https://doi.org/10.1182/blood-2003-08-2804
  3. Foy, M., Treumann, A., Fitzgerald, D. J., Maguire, P. B., & Kerrigan, S. K. (2004). Characterization of platelet lipid rafts leads to the identification of RGS-19, which forms a phosphorylation-dependent complex with 14-3-3 xi. Blood, 104(11), 181A-181A. (opens in a new window)https://doi.org/10.1182/blood.V104.11.625.625

2002

  1. Maguire, P. B., Wynne, K. J., Harney, D. F., O'Donoghue, N. M., Stephens, G., & Fitzgerald, D. J. (2002). Identification of the phosphotyrosine proteome from thrombin activated platelets. Proteomics, 2(6), 642-648. (opens in a new window)https://doi.org/10.1002/1615-9861(200206)2:6<642::aid-prot642>3.0.co;2-i

1999

  1. Ohlendieck, K., Fromming, G. R., Murray, B. E., Maguire, P. B., Leisner, E., Traub, I., & Pette, D. (1999). Effects of chronic low-frequency stimulation on Ca2+-regulatory membrane proteins in rabbit fast muscle. Pflugers Archiv-European Journal of Physiology, 438(5), 700-708. (opens in a new window)https://doi.org/10.1007/s004240051096

1996

  1. Maguire, P. B., & Ohlendieck, K. (1996). Oligomerization of sarcoplasmic reticulum Ca2+-ATPase from rabbit skeletal muscle. Febs Letters, 396(2-3), 115-118. https://doi.org/10.1016/0014-5793(96)01106-4

Contact Conway SPHERE Research Group

UCD Conway Institute, University College Dublin, Belfield, Dublin 4, Ireland.
T: +353 1 716 6700