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Minister O’Donovan announces €26million for 40 research projects

Wednesday, 23 October, 2024

  • Environmental sustainability, electric vehicle battery technologies, breast cancer, and childhood neurological disorders among the initiatives supported

Fionnuala O’Leary, Chief Executive Officer, Children’s Health Foundation (co-funder); Dr Ruth Freeman, Director, Science for Society at Research Ireland; Minister Patrick O'Donovan TD; and Dr Fiona Freeman, UCD, whose research project focuses on treating bone cancer among children, teenagers and young adults.

Minister for Further and Higher Education, Research, Innovation and Science, Patrick O’Donovan TD, has today announced funding of €26 million for 40 research projects.

Funded under the Taighde Éireann – Research Ireland Frontiers for the Future Programme, the projects address key areas such as environmental sustainability, new EV battery technologies, breast cancer, inflammatory bowel disease, and currently untreatable childhood neurological disorders.

As a Frontiers for the Future partner, Children’s Health Foundation is funding two of the 40 projects (childhood epilepsy and cystic fibrosis) and co-funding another project with Research Ireland (bone cancer).

Welcoming the announcement, Minister O’Donovan said: “I am pleased to announce the Research Ireland Frontiers for the Future projects, which support high-risk, high-reward research endeavours. The selected projects, spanning 12 research institutions, bring fresh and innovative ideas that will help boost business and benefit society.

“I would also like to commend Research Ireland and the Children’s Health Foundation for their great partnership and their focus on advancing children’s health through this funding program. I encourage others to create similar partnerships and collaborations.”

Among the other projects to receive funding are:

  • A gene therapy combined with tissue engineering to reduce scarring and help promote nerve regeneration after spinal cord injury
  • Understanding the stability of large icesheets in Greenland and Antarctica in response to global warming
  • Novel therapies for severe, currently untreatable childhood-neurological disorders
  • Alternative battery technologies for Electric Vehicles
  • Assistance dogs with collar sensors to signal and alert of impending seizures to patients and their carers
  • Studying preserved bog plants to better understand what drought bogs can survive
  • Biosensors in 4D food printing that indicate strength and stability of probiotics

Celine Fitzgerald, Interim Chief Executive Officer, Research Ireland, commented: “The Research Ireland Frontiers for the Future programme helps to build research capacity, expertise and reputation. This latest round of grants will support a diverse range of research positions and represents a strong commitment to developing future talent in key areas. It has been a pleasure having Children’s Health Foundation as a funding partner in that drive to strengthen Ireland’s research pipeline.”

Fionnuala O’Leary, Chief Executive Officer, Children’s Health Foundation, commented: “Children’s Health Foundation is a proud partner of Frontiers for the Future programme, and we are delighted to co-fund paediatric research projects that will benefit sick children throughout Ireland. Working with Research Ireland, we are able to leverage the funds our incredible supporters raise, to deliver larger grants for research into childhood diseases. This ensures the tireless efforts of our fundraisers can result in kinder and more gentler treatments for sick children. Frontiers for the Future programme plays a key role in enabling us to fund paediatric research with the potential to deliver impact for sick children now and into the future.”

The research will be undertaken in the following research bodies for a period of 2-4 years:

  • University College Cork
  • Dublin Institute for Advanced Studies
  • University of Limerick
  • University College Dublin
  • Trinity College Dublin
  • University of Galway
  • Technological University Dublin
  • Dublin City University
  • Tyndall National Institute
  • Teagasc
  • Maynooth University
  • RCSI University of Medicine and Health Sciences

UCD projects:

Associate Prof Fiona Freeman, Ad Astra Fellow at UCD School of Mechanical and Materials Engineering and Conway Fellow, and Dr Scheryll Alken, Children's Health Ireland: Conjugated STING-agonist nanoparticles as novel therapeutic add-on to enhance the therapeutic response of chemotherapy for the treatment of osteosarcoma.

Associate Prof Vikram Pakrashi, UCD School of Mechanical and Materials Engineering / Dr Michelle Carey, UCD School of Mathematics and Statistics:
Energy Harvesting for Monitoring Built Infrastructure : HarMonI

Dr Rebecca Henry, UCD School of Biomolecular and Biomedical Science and Conway Fellow:
Investigation of the role of the GDF-15/GFRAL signalling axis in mediating neuroprotective effects in the presence of co-morbid diet-induced obesity and TBI.

Dr Áine Byrne, UCD School of Mathematics and Statistics :
Bridging the gap for mathematical models of gap junctions.

Prof Cormac Murphy, UCD School of Biomolecular and Biomedical Science and Conway Fellow:
Mapping the biochemical steps of microbial PFOA metabolism.

Associate Prof Niamh O'Sullivan, UCD School of Biomolecular and Biomedical Science and Conway Fellow:
Developing novel therapeutic strategies for neurodegenerative disease

Dr Gary Brennan, UCD School of Biomolecular and Biomedical Science and Conway Fellow:
Long non-coding RNA-mediated cellular dysfunction in acquired and genetic epilepsies

Associate Prof Eoghan McGarrigle, UCD School of Chemistry:
BendZymes – Novel Catalysts for Glyco Applications

Dr Dearbhaile Dooley, UCD School of Medicine and Conway Fellow:
Targeting Inflammatory Signaling between Microglia and Astroglia in spinal cord injury.

Dr Marina Rubini, UCD School of Chemistry:
Site-specific chemical modifications of human Interferon-gamma for improved therapeutics

Dr Leila Negahdar, UCD School of Chemistry:
Programming catalytic surface reactions with dynamic kinetic oscillations

UCD College of Engineering and Architecture

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