IMPACT CASE STUDY

Supporting cancer patients to quit smoking post diagnosis

  • 25 January 2025
  • Professor Patricia Fitzpatrick
  • Academic, Educational, Health, Social

 

Summary

Professor Fitzpatrick’s research findings impact all patients with cancer who smoke. Patients with cancer who smoke (up to 20% of all diagnosed) are not currently offered support to quit, despite evidence of the benefits of quitting after a cancer diagnosis. These benefits include improved treatment outcomes, fewer treatment complications, improved survival rates and positive effects on health. The impacts of Professor Fitzpatrick’s research are national and international; the research was adopted in full by the HSE National Cancer Control Programme and is a priority for 2024.

3,744 - 4,959 patients with cancer, and their families, will benefit each year. The research was reported in national media and a podcast on the research has been released by the European School of Oncology. The research team have published widely in academic and professional healthcare publications. 

Research description

The benefits of quitting smoking after a cancer diagnosis are undervalued, despite substantial evidence. Continued smoking is associated with treatment complications and toxicities in the body, increased risk of recurrence, new smoking-related cancers of another type, lower survival and diminished quality of life. But many diagnosed with cancer continue smoking and do not receive support to help them stop. 

This Irish Cancer Society-funded research was co-developed with cancer patients who smoke to develop a way to help them cease smoking. The project comprised a number of stages. At the outset of the project, Professor Fitzpatrick participated in a Patient Voice in Cancer Research Dragon’s Den event to present the study plan and seek input. The research team then established a steering committee and invited people with lived experience, academics and practice experts to take part. The research team published a rapid systematic review examining relevant practices to help patients stop smoking and analysed smoking rates among cancer patients using a national hospital discharge database (2014-2018). As well as this, Professor Fitzpatrick audited all 8 adult specialist cancer hospitals and the major radiotherapy centre against national clinical guidelines. The team completed interviews with patients attending four cancer hospitals and oncology healthcare professionals and the results were discussed at a Patient Voice in Cancer Research workshop. 

The rapid systematic review identified discrepancies in interventions designed to help smokers with a cancer diagnosis to quit. It identified a lack of trained professionals who could provide this support; a similar lack of hospital smoking cessation officers and referral practices to smoking cessation services were also noted in the audit. The team found that although there has been a drop in smoking rates amongst the general population, smoking rates in patients with cancer have not fallen in line with this. Qualitative analysis of patient interviews found a willingness to be repeatedly approached and supported to quit, and it outlined the need for sustained, non-judgemental support across hospital and community settings and the importance of healthcare practitioners and family as facilitators of the process of quitting. Interviews with healthcare professionals identified the importance of prioritising the therapeutic relationship with patients while maintaining a willingness from them to discuss quitting. However, they also outlined challenges in starting the conversation given heavy workloads and a lack of knowledge around the relevant support services available. 

 

Research team

 

  • Core research team: Professor Patricia Fitzpatrick (PI), Dr Nancy Bhardwaj, Dr Patricia Fox, Associate Professor Kate Frazer, Dr Ailsa Lyons, and Professor Amanda McCann.
  • Associated UCD team members – assisted with analysis and/or write up of articles: Dr Mouayad Masalkhi, Dr Vikram Niranjan, Dr Shiraz Syed.
  • Collaborators – facilitated patient and healthcare professional recruitment: Prof Sinead Brennan (St. Luke’s Radiation Oncology Network (SLRON)), Mr. James Geraghty (St Vincent’s University Hospital (SVUH)), Prof Michael Keane (SVUH), Associate Prof Cathy Kelly (Mater Misericordiae University Hospital (MMUH), Mater Private Hospital), Prof Donal Brennan (MMUH), Paula Briscoe, Aidin Roberts, Dr Paul Nevins Selvadurai (MMUH), Lisa Cadden, Santy Manoj (SVUH), and Fiona Gilbert (SLRON).
  • Professor Cecily Kelleher (UCD).
  • Patient panel – involved questionnaire design, study guidance, authors on published abstracts/articles: Ms Marie Johnson, Mr Seamus Quinn, Mr John Wall.

 

Funding

 

  • This research was funded by the Irish Cancer Society in 2019 (SCAFIT2019 €64,999) to start in January 2020. Due to COVID-19 this predominantly hospital-related research had to be suspended for several months and then restarted.

Research impact

Health impact

Professor Fitzpatrick’s research findings were presented to Tobacco Free Ireland (TFI), the Irish Cancer Society and the National Cancer Control Programme (NCCP). Findings were consequently adopted by the NCCP, supported by TFI, and smoking cessation for cancer patients was made an NCCP priority for 2024 with a team assigned to lead on it. This will inform the next National Cancer Strategy. 

The impact is greatest for patients  attending Ireland’s 8 specialist cancer centres and associated radiotherapy centres. In 2016 the inpatient smoking rate was 15.1% in St Vincent’s University Hospital. However, findings elsewhere suggest 20% of patients with cancer smoke. Over 2018-2020, the National Cancer Registry reported the average number of patients with invasive cancer in Ireland as 24,793. Therefore, between 3,744 and 4,959 patients (15.1%-20%) and their families are set to benefit each year. Smoking cessation benefits family health by reducing passive smoking; the risk of lung cancer in a non-smoking spouse of a smoker is 15% and the risk of cardiovascular disease is up to 20%. 

One Patient and Public Involvement panel member stated, “I finally gave up smoking thanks to this study along with the help of the Mater Hospital smoking cessation team”. 

Educational impact

The team’s findings have been incorporated into postgraduate teaching in the School of Nursing, Midwifery and Health Systems in UCD with immediate impact.

Feedback from a Cancer Nursing student following placement with a smoking cessation officer in a cancer hospital said: “I realised on immediate reflection of my time with the officer that I have never been good at being upfront with patients who should advisably stop smoking. I am reluctant to upset patients and perhaps have felt in the past if I talk about smoking very openly it would upset them. I have become more confident in opening the conversation and less fearful of a negative reaction. I now have the discussion, and I am more confident speaking to them about nicotine replacement therapy and advising them about the HSE Quit.ie website”. A medical student was also involved in some parts of this research and learned about conducting research.

The European School of Oncology also created a podcast dedicated to the findings of the study. The team were asked to contribute two articles for Irish Pharmacy News in May 2023 called "Smoking Cessation for Patients with Cancer – the role of the Pharmacist" and "Smoking Cessation in 2023", which were circulated to all pharmacies in Ireland.

The team were also asked to contribute a further article for Hospital Professional News  in May 2023 for circulation to all hospital professionals called Smoking Cessation for Patients with Cancer – the role of the Pharmacist.  The team were asked to contribute to the Hospital Inpatient Enquiry coding notes newsletter which was circulated to all hospitals in Ireland. 

Academic impact

The research led to 6 published articles, the publication of a Prospero protocol, and presentations at 9 international and 11 national meetings. Abstracts of the research were published in the Lancet and European Journal of Public Health. 

Social impact

The study findings have been reported in national print media and radio, including prominent Irish newspaper the Irish Independent and on the radio stations Spin 1038 and Classic Hits.

 

“This research represents an extremely valuable contribution to the NCCP in ensuring that smokers diagnosed with cancer are given appropriate smoking cessation supports in line with the recommendations of the National Cancer Strategy 2017-2026. Their findings will be integral to the work of the NCCP in developing effective smoking cessation pathways tailored for those living with and beyond cancer in Ireland”. 

- Dr Breeda Neville, National Cancer Control Programme (NCCP) 

“The UCD team effectively and sensitively shone a light on an important gap in cancer care. Importantly, through a careful mix of methods and close partnership with patients and service providers, they have built a better understanding of this care gap and provided evidence-based recommendations. The TFI programme looks forward to collaborating with NCCP to implement improvements leading to better health, experience and outcomes for people living with and beyond cancer”. 

- Dr Paul Kavanagh, HSE Tobacco Free Ireland (TFI) Programme 

Published articles 

  • Frazer K, Bhardwaj N, Fox P, Syed S, Lyons A, McCann A, Niranjan V, Kelly C, Brennan S, Brennan D, Geraghty J, Keane MP, Fitzpatrick P. A qualitative study to understand the barriers and facilitators in smoking cessation practices among oncology health care practitioners in one health system. Nicotine and Tobacco Research (in press 2024) https://doi.org/10.1093/ntr/ntae185 
  • Fox P, Bhardwaj N, Lyons A, Frazer K, Syed S, McCann A, Brennan S, Brennan D, Kelly C, Keane M, Fitzpatrick P. Smoking Cessation Support: A Marathon, not a Sprint; The Perspectives of Cancer Patients who Smoke. Seminars in Oncology Nursing 2024;40:151584. doi: https://doi.org/10.1016/j.soncn.2024.151584 
  • Lyons A, Bhardwaj N, Masalkhi M, Fox P, Frazer K, McCann A, Syed S, Niranjan V, Kelleher CC, Kavanagh P, Fitzpatrick P. Specialist Cancer Hospital-based Smoking Cessation Service Provision in Ireland. Irish Journal of Medical Science 2024 Apr;193(2):629-638. doi: 10.1007/s11845-023-03525-0. Epub 2023 Sep 23.PMID: 37740109 
  • Fitzpatrick P, Bhardwaj N, Masalkhi M, Lyons A, Frazer K, McCann A, Syed S, Niranjan V, Kelleher CC, Brennan S, Kavanagh P, Fox P. Provision of smoking cessation support for patients following a diagnosis of cancer in Ireland. Preventive Medicine Reports 2023 Feb 20; 32:102158. doi: 10.1016/j.pmedr.2023.102158. eCollection 2023 Apr.PMID: 36875512 
  • Frazer K, Bhardwaj N, Fox P, Stokes D, Niranjan V, Quinn S, Kelleher CC, Fitzpatrick P. A. Systematic Review of Smoking Cessation Interventions for Smokers Diagnosed with Cancer. International Journal of Environmental Research and Public Health 2022, 19(24), 17010 https://doi.org/10.3390/ijerph192417010 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9779002/ 
  • Fitzpatrick P, Bhardwaj N, Lyons A, Doherty K, Frazer K, McCann A, Niranjan V, Syed S, Fox P. Has the national fall in smoking rate in Ireland been replicated in cancer patients? a 5-year report. International Journal of Environmental Resarch Public Health. 2022 Feb 18;19(4):2348. doi: 10.3390/ijerph19042348 PMID: 35206536; PMCID: PMC8874430 

Published abstracts 

  • Frazer K, Bhardwaj N, Fox P, Niranjan V, Stokes D, Quinn S, Kelleher CC, Fitzpatrick P. A systematic review of smoking cessation interventions for smokers diagnosed with cancer. UK Public Health Science conference 2022. Lancet Volume 400 Special Issue 1 S39 Public Health Science 2022 Published Nov 2022. https://doi.org/10.1016/S0140-6736(22)02249-8 
  • Frazer K, Bhardwaj N, Fox P, Lyons A, Niranjan V, Syed S, McCann A, Quinn E, Quinn S, Wall J, Johnson M, Fitzpatrick P. Using a five-stage approach to embed Patient and Public Involvement in the co design of a smoking cessation pathway for people who smoke and have a diagnosis of cancer. European Public Health Association (EUPHA) Conference, Dublin, November 2023 European Journal of Public Health, Volume 33, Issue Supplement_2, October 2023, ckad160.1403, https://doi.org/10.1093/eurpub/ckad160.1403. 
  • Fitzpatrick P, Bhardwaj N, Syed S, Fox P, Frazer K, Niranjan V, Lyons A, McCann A, Brennan S, Guerin S. Smoking cessation for cancer patients through the lens of cancer specialists: challenges & solutions. European Public Health Association (EUPHA) Conference, Berlin, November 2022. European Journal of Public Health, Volume 32, Issue Supplement_3, October 2022, ckac131.017, https://doi.org/10.1093/eurpub/ckac131.017 

Podcast 

  • Fox, P. (2023) Smoking Cessation in Patients with Cancer. [Podcast]. 25 May 2023. Available at: https://www.e-eso.net/sessions/3614.