| Professor Alan Baird |
| Maher, S, Medani, M,Carballeira, NN, Nestor N, Winter, DC, Baird, AW, Brayden, DJ. (2017) 'Development of a Non-Aqueous Dispersion to Improve Intestinal Epithelial Flux of Poorly Permeable Macromolecules'. AAPS Journal, 19 (1):244-253. |
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| Udupa VK, Winter DC, Baird AW (2016) 'RAGE-ligand axis: A new biomarker in multiple sclerosis, time for multicentre validation study!'. Immunobiology, 221 (9):1012-1013. |
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| Assoc Professor John Andrew Baugh |
| Li L, Watson CJ;Dubourd M;Bruton A;Xu M;Cooke G;Baugh JA (2016) 'HIF-1-Dependent TGM1 Expression is Associated with Maintenance of Airway Epithelial Junction Proteins'.Lung, 194 (5):829-838. |
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| Assoc Professor Orina Belton |
| Brennan E, Wang B;McClelland A;Mohan M;Marai M;Beuscart O;Derouiche S;Gray S;Pickering R;Tikellis C;de Gaetano M;Barry M;Belton O;Ali-Shah ST;Guiry P;Jandeleit-Dahm KA;Cooper ME;Godson C;Kantharidis P (2017) 'Protective Effect of Let-7 miRNA Family in Regulating Inflammation in Diabetes-Associated Atherosclerosis'. Diabetes . |
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| Brennan E, Wang B;McClelland A;Mohan M;Marai M;Beuscart O;Derouiche S;Gray S;Pickering R;Tikellis C;de Gaetano M;Barry M;Belton O;Ali-Shah ST;Guiry P;Jandeleit-Dahm KA;Cooper ME;Godson C;Kantharidis P (2017) 'Protective Effect of Let-7 miRNA Family in Regulating Inflammation in Diabetes-Associated Atherosclerosis'. Diabetes . |
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| McEvoy C, de Gaetano M;Giffney HE;Bahar B;Cummins EP;Brennan EP;Barry M;Belton O;Godson CG;Murphy EP;Crean D (2017) 'NR4A Receptors Differentially Regulate NF-¿¿B Signaling in Myeloid Cells'. Frontiers in Immunology, 8 . |
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| McEvoy C, de Gaetano M, Giffney HE, Bahar B, Cummins EP, Brennan EP, Barry M, Belton O, Godson CG, Murphy EP, Crean D. (2017) 'NR4A Receptors Differentially Regulate NF-κB Signaling in Myeloid Cells'. Frontiers in Immunology . |
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| McEvoy C, de Gaetano M, Giffney HE, Bahar B, Cummins EP, Brennan EP, Barry M, Belton O, Godson CG, Murphy EP and Crean D (2017) 'Receptors Differentially Regulate NF-κB Signaling in Myeloid Cells'. Frontiers in Immunology, 8 (7). |
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| Assoc Professor Oliver Blacque |
| Jensen VL, Carter S, Sanders AAWM, Li C, Kennedy J, Timbers TA, Cai J, Scheidel N, Kennedy BN, Morin RD, Leroux MR, Blacque OE. (2016) 'Whole-Organism Developmental Expression Profiling Identifies RAB-28 as a Novel Ciliary GTPase Associated with the BBSome and Intraflagellar Transport'. PLoS Genetics . |
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| Nechipurenko IV, Olivier-Mason A, Kazatskaya A, Kennedy J, McLachlan IG, Heiman MG, Blacque OE, Sengupta P (2016) 'A conserved role for Girdin in basal body positioning and ciliogenesis'. Developmental Cell . |
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| Professor Billy Bourke |
| Coughlan A, Wylde R, Lafferty L, Quinn S, Broderick A, Bourke B, Hussey S (2017) 'A rising incidence and poorer male outcomes characterise early onset paediatric inflammatory bowel disease'. Alimentary Pharmacology and Therapeutics, 45 (12):1534-1541. |
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| Stenke E, Bourke B, Knaus U (2017) 'Crohn's disease - moving away from the knife'.Frontiers . |
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| Scanlan E, Ardill L, Whelan MV, Shortt C, Nally JE, Bourke B, Ó Cróinín T (2017) 'Relaxation of DNA supercoiling leads to increased invasion of epithelial cells and protein secretion by Campylobacter jejuni'. Molecular Microbiology, 104 (1):92-104. |
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| Alvarez,LA; Kovacic, L; Rodriguez, J; Gosemann, JH; Kubica, M; Pircalabioru, GG; Friedmacher, F; Cean, A; Ghise, A; Sarandan, MB; Puri, P; Daff, S; Plettner, E; von Kriegsheim, A; Bourke, B; Knaus, UG (2016) 'NADPH oxidase-derived H2O2 subverts pathogen signaling by oxidative phosphotyrosine conversion to PB-DOPA'. Proceedings of the National Academy of Sciences of the United States of America, 113 (37):10406-10411. |
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| Shortt C, Scanlan E, Hilliard A, Cotroneo CE, Bourke B, Ó Cróinín T. (2016) 'DNA Supercoiling Regulates the Motility of Campylobacter jejuni and Is Altered by Growth in the Presence of Chicken Mucus'. mBio, 13 (5):e01227-16-e01227-16. |
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| Professor David Brayden |
| Ahmad T, Gogarty M;Walsh E;Brayden DJ (2017) 'A comparison of three Peyer's patch M-like cell culture models: particle uptake, bacterial interaction, and epithelial histology'.European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V . |
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| Beloqui A, Brayden DJ;Artursson P;Preat V;des Rieux A (2017) 'A human intestinal M-cell-like model for investigating particle, antigen and microorganism translocation'. Nature Protocols, 12 (7):1387-1399. |
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Grasso, S., Harrison, S. M., Monahan, F. J., Brayden, D., Brunton, N. P. (2017) 'The effect of plant sterol-enriched turkey meat on cholesterol bio-accessibility during in vitro digestion and Caco-2 cell uptake'. International Journal of Food Sciences and Nutrition, 9 :1-7.  |
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| Gleeson JP, Brayden DJ;Ryan SM (2017) 'Evaluation of PepT1 transport of food-derived antihypertensive peptides, Ile-Pro-Pro and Leu-Lys-Pro using in vitro, ex vivo and in vivo transport models'. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 115 :276-284. |
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| Bhattacharjee S, Mahon E;Harrison SM;McGetrick J;Muniyappa M;Carrington SD;Brayden DJ (2016) 'Nanoparticle passage through porcine jejunal mucus: Microfluidics and rheology'. Nanomedicine, 13 (3):863-873. |
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| Maher S, Medani M;Carballeira NN;Winter DC;Baird AW;Brayden DJ (2016) 'Development of a Non-Aqueous Dispersion to Improve Intestinal Epithelial Flux of Poorly Permeable Macromolecules'. The AAPS journal, 19 (1):244-253. |
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| Maher. S, Medani, M., Carballeira, N.M., Winter, D.C., Baird, A.W., & Brayden D. J. (2016) 'Development of a non-aqueous dispersion to improve intestinal epithelial flux of poorly permeable macromolecules'. AAPS Journal, In Process . |
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| Professor Lorraine Brennan |
| Brennan, L. (2017) 'The nutritional metabolomics crossroads: how to ensure success for dietary biomarkers'. American Journal of Clinical Nutrition, 105 :293-294. |
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| O'Gorman, A.; Brennan, L. (2017) 'The role of metabolomics in determination of new dietary biomarkers'. Proceedings of the Nutrition Society . |
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| Celis-Morales C, Livingstone KM;Marsaux CF;Macready AL;Fallaize R;O'Donovan CB;Woolhead C;Forster H;Walsh MC;Navas-Carretero S;San-Cristobal R;Tsirigoti L;Lambrinou CP;Mavrogianni C;Moschonis G;Kolossa S;Hallmann J;Godlewska M;Surwi¿¿¿¿o A;Traczyk I;Drevon CA;Bouwman J;van Ommen B;Grimaldi K;Parnell LD;Matthews JN;Manios Y;Daniel H;Martinez JA;Lovegrove JA;Gibney ER;Brennan L;Saris WH;Gibney M;Mathers JC; (2017) 'Effect of personalized nutrition on health-related behaviour change: evidence from the Food4me European randomized controlled trial'.International Journal of Epidemiology, 46 (2):578-588. |
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| Gibbons, H.R.; Carr, E.; McNulty, B.A.; Nugent, A.P.; Walton, J.; Flynn, A.; Gibney, M.J.; Brennan, L. (2017) 'Metabolomic based identification of clusters that reflect dietary patterns'. Molecular Nutrition and Food Research . |
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| Gibbons, H.; Michielsen, C.J.R.; Rundle, M.; Frost, G.; McNulty, B.A.; Nugent, A.P.; Walton, J.; Flynn, A.; Gibney, M.J.; Brennan, L. (2017) 'Demonstration of the utility of biomarkers for dietary intake assessment; proline betaine as an example'. Molecular Nutrition and Food Research . |
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| Albani, V.; Celis-Morales, C.; O¿Donovan, C.B.; Walsh, M.C.; Woolhead, C.; Forster, H.; Fallaize, R.; Macready, A.L.; Marsaux, C.F.M.; Navas-Carretero, S.; San-Cristobal, R.; Kolossa, S.; Mavrogianni, C.; Lambrinou, C.P.; Moschonis, G.; Godlewska, M.; Surwillo, A.; Traczyk, I.; Gundersen, T.E.; Drevon, C.A.; Daniel, H.; Manios, Y.; Martinez, J.A.; Saris, W.H.M.; Lovegrove, J.A.; Gibney, M.J.; Gibney, E.R.; Mathers, J.C.; Adamson, J.A.; Brennan, L: (2017) 'Within-person reproducibility and sensitivity to dietary change of C15:0 and C17:0 levels in dried blood spots: data from the European Food4Me Study'.Molecular Nutrition and Food Research . |
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| Celis-Morales C, Marsaux CF;Livingstone KM;Navas-Carretero S;San-Cristobal R;Fallaize R;Macready AL;O'Donovan C;Woolhead C;Forster H;Kolossa S;Daniel H;Moschonis G;Mavrogianni C;Manios Y;Surwillo A;Traczyk I;Drevon CA;Grimaldi K;Bouwman J;Gibney MJ;Walsh MC;Gibney ER;Brennan L;Lovegrove JA;Martinez JA;Saris WH;Mathers JC (2017) 'Can genetic-based advice help you lose weight? Findings from the Food4Me European randomized controlled trial'. The American journal of clinical nutrition, 105 (5):1204-1213. |
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| O'Gorman, Aoife; Gibbons, Helena; Ryan, Miriam; Gibney, Eileen R.; Gibney, Michael; Frost, Gary; Roche, Helen; Brennan, Lorraine (2017) 'Exploring the links between diet and health in an Irish cohort: A lipidomic approach'. Journal of Proteome Research . |
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| Zhao Y, Monahan FJ;McNulty BA;Li K;Bloomfield FJ;Duff DJ;Brennan L;Nugent AP;Gibney ER (2017) 'Plasma n-3 polyunsaturated fatty status and its relationship with vitamin E intake and plasma level'. European Journal of Nutrition, 56 (3). |
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| Livingstone KM, Celis-Morales C;Macready AL;Fallaize R;Forster H;Woolhead C;O'Donovan CB;Marsaux CF;Navas-Carretero S;San-Cristobal R;Kolossa S;Tsirigoti L;Lambrinou CP;Moschonis G;Surwi¿¿¿¿o A;Drevon CA;Manios Y;Traczyk I;Gibney ER;Brennan L;Walsh MC;Lovegrove JA;Martinez JA;Saris WH;Daniel H;Gibney M;Mathers JC (2017) 'Characteristics of European adults who dropped out from the Food4Me Internet-based personalised nutrition intervention'. Public Health Nutrition, 20 :53-63. |
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| Manios, Y.; Moschonis, G.; Lambrinou, C.P.; Mavrogianni, C.; Tsirigoti, L.; Hoeller, U.; Roos, F.F.; Bendik, I.; Eggersdorfer, M.; Celis-Morales, C.; Livingstone, K.M.; Marsaux, C.F.; Macready, A.L.; Fallaize, R.; O'Donovan, C.B. Woolhead, C.; Forster, H.; Walsh, M.C.; Navas-Carretero, S.; San-Cristobal, R.; Kolossa, S.; Hallmann, J.; Jarosz, M.; Surwiłło, A.; Traczyk, I.; Drevon, C.A.; van Ommen, B.; Grimaldi, K.; Matthews, J.N.; Daniel, H.; Martinez, J.A.; Lovegrove, J.A.; Gibney, E.R.; Brennan, L.; Saris, W.H.; Gibney, M.; Mathers, J.C.; the Food4Me Study (2017) 'Associations of vitamin D status with dietary intakes and physical activity levels among adults from seven European countries: the Food4Me study'. European Journal of Nutrition . |
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| Branco, J.; Ola, M.; Silva, R.M.; Fonseca, E.; Gomes, N.C.; Martins-Cruz, C.; Silva, A.P.; Silva-Dias, A.; Pina-Vaz, C.; Erraught, C.; Brennan, L.; Rodrigues, A.G.; Butler, G.; Miranda, I.M. (2017) 'Impact of ERG3 mutations and expression of ergosterol genes controlled by UPC2 and NDT80 in Candida parapsilosis azole resistance'. Clinical Microbiology and Infection . |
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| Brennan, L. (2017) 'Metabolomics in nutrition research-a powerful window into nutritional metabolism'. Essays in Biochemistry, 60 :451-458. |
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| O'Donovan, C.B.; Walsh, M.C.; Gibney, M.J.; Brennan, L.; Gibney, E.R. (2017) 'Knowing your genes: does this impact behaviour change?'. Proceedings of the Nutrition Society . |
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| Cheung, W.; Keski-Rahkonen, P.; Assi, N.; Ferrari, P.; Freisling, H.; Rinaldi, S.; Slimani, N.; Zamora-Ros, R.; Rundle, M.; Frost, G.; Gibbons, H.; Carr, E.; Brennan, L.; Cross, A.J.; Pala, V.; Panico, S.; Sacerdote, C.; Palli, D.; Tumino, R.; Kühn, T.; Kaaks, R.; Boeing, H.; Floegel, A.; Mancini, F.; Boutron-Ruault, M.C.; Baglietto, L.; Trichopoulou, A.; Naska, A.; Orfanos, P.; Scalbert, A. . Am J Clin Nutr 2017, 105: 600-608 (2017) 'A metabolomic study of biomarkers of meat and fish intake'. American Journal of Clinical Nutrition . |
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| Kirwan, L.; Walsh, M.C.; Celis-Morales, C.; Marsaux, C.F.M.; Livingstone, K.M.; Navas-Carretero, S.; Fallaize, R.; O¿Donovan, C.; Woolhead, C.; Forster, H.; Kolossa, S.; Daniel, H.; Moschonis, G.; Manios, Y.; Surwillo, A.; Godlewska, A.; Traczyk, I.; Drevon, C.A.; Gibney, M.J.; Lovegrove, J.A.; Martinez, J.-A.; Saris W.H. M.; Mathers, J.C.; Gibney, E.R.; Brennan, L. on behalf of the Food4me study (2017) 'Phenotypic factors influencing the variation in response of circulating cholesterol level to personalised dietary advice in the Food4me study'. British Journal of Nutrition . |
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| Gibbons, H.; Brennan, L. (2017) 'Metabolomics as a tool in the identification of dietary biomarkers'. Proceedings of the Nutrition Society, 76 :42-53. |
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| Brennan, L. (2017) 'Use of metabotyping for optimal nutrition'. Current Opinion in Biotechnology, 44C :35-38. |
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| Livingstone KM, Celis-Morales C, Lara J, Woolhead C, O'Donovan CB, Forster H, Marsaux CF, Macready AL, Fallaize R, Navas-Carretero S, San-Cristobal R, Kolossa S, Tsirigoti L, Lambrinou CP, Moschonis G, Surwiłło A, Drevon CA, Manios Y, Traczyk I, Gibney ER, Brennan L, Walsh MC, Lovegrove JA, Martinez JA, Saris WH, Daniel H, Gibney M, Mathers JC (2016) 'Clustering of adherence to personalised dietary recommendations and changes in healthy eating index within the Food4Me study'. Public Health Nutrition, 19(18):3296-3305 (19(18):3296-3305):19(18):3296-3305-19(18):3296-3305. |
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| Narancic T, Scollica E;Kenny ST;Gibbons H;Carr E;Brennan L;Cagney G;Wynne K;Murphy C;Raberg M;Heinrich D;Steinb¿¿chel A;O'Connor KE (2016) 'Understanding the physiological roles of polyhydroxybutyrate (PHB) in Rhodospirillum rubrum S1 under aerobic chemoheterotrophic conditions'. Applied Microbiology and Biotechnology, 100 (20):8901-8912. |
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| O'Donovan CB, Walsh MC, Forster H, Woolhead C, Celis-Morales C, Fallaize R, Macready AL, Marsaux CF, Navas-Carretero S, San-Cristobal R, Kolossa S, Mavrogianni C, Lambrinou CP, Moschonis G, Godlewska M, Surwillo A, Bouwman J, Grimaldi K, Traczyk I, Drevon CA, Daniel H, Manios Y, Martinez JA, Saris WH, Lovegrove JA, Mathers JC, Gibney MJ, Brennan L, Gibney ER (2016) 'The impact of MTHFR 677C → T risk knowledge on changes in folate intake: findings from the Food4Me study'. Genes and Nutrition, Sept (29):11-25. |
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| Livingstone KM, Celis-Morales C, Hoeller U, Lambrinou CP, Moschonis G, Macready AL, Fallaize R, Baur M, Roos FF, Bendik I, Grimaldi K, Navas-Carretero S, San-Cristobal R, Weber P, Drevon CA, Manios Y, Traczyk I, Gibney ER, Lovegrove JA, Saris WH, Daniel H, Gibney M, Martinez JA, Brennan L, Hill TR, Mathers JC; Food4Me Study.. (2016) 'Weekday sunlight exposure, but not vitamin D intake, influences the association between vitamin D receptor genotype and circulating concentration 25-hydroxyvitamin D in a pan-European population: the Food4Me study'. Molecular Nutrition and Food Research . |
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| Fallaize R, Celis-Morales C, Macready AL, Marsaux CF, Forster H, O'Donovan C, Woolhead C, San-Cristobal R, Kolossa S, Hallmann J, Mavrogianni C, Surwillo A, Livingstone KM, Moschonis G, Navas-Carretero S, Walsh MC, Gibney ER, Brennan L, Bouwman J, Grimaldi K, Manios Y, Traczyk I, Drevon CA, Martinez JA, Daniel H, Saris WH, Gibney MJ, Mathers JC, Lovegrove JA; Food4Me Study.. (2016) 'The effect of the apolipoprotein E genotype on response to personalized dietary advice intervention: findings from the Food4Me randomized controlled trial'. American Journal of Clinical Nutrition, 104(3):827-36 (104(3):827-36):104(3):827-36-104(3):827-36. |
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| Professor Geraldine Butler |
| Schröder MS, Martinez de San Vicente K, Prandini TH, Hammel S, Higgins DG, Bagagli E, Wolfe KH, Butler G. (2016) 'Multiple origins of the pathogenic yeast Candida orthopsilosis by separate hybridizations between two parental species'. PLoS Genetics, 12 :e1006404. |
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| Donovan PD, Schröder MS, Higgins DG, Butler G. (2016) 'Identification of Non-Coding RNAs in the Candida parapsilosis Species Group'. PLoS ONE, 11 :e0163235. |
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| Dr Gerard Cagney |
| Kranjc T, Dempsey E, Cagney G, Nakamura N, Shields DC, Simpson JC. (2017) 'Functional characterisation of the YIPF protein family in mammalian cells'. Histochemistry and Cell Biology, 147 :439-451. |
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| Butler CT, Reynolds AL, Tosetto M, Dillon ET, Cagney G, O¿Sullivan J & Kennedy BN. (2017) 'A Quininib Analogue and Cysteinyl Leukotreine Receptor Antagonist Inhibits VEGF-Independent Angiogenesis and Exerts an Additive Anti-angiogenic Response with Bevacizumab'. Journal of Biological Chemistry, 292 (9):3552-3567. |
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| De Chiara, L., Andrews, D., Watson, A., Oliviero, G., Cagney, G. and Crean, J. (2017) 'miR302 regulates SNAI1 expression to control mesangial cell plasticity'. Scientific Reports. |
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| Sabherwal S, English JA;F¿¿cking M;Cagney G;Cotter DR (2016) 'Blood biomarker discovery in drug-free schizophrenia: the contribution of proteomics and multiplex immunoassays'. Expert Review of Proteomics . |
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| Narancic T, Scollica E;Kenny ST;Gibbons H;Carr E;Brennan L;Cagney G;Wynne K;Murphy C;Raberg M;Heinrich D;Steinb¿¿chel A;O'Connor KE (2016) 'Understanding the physiological roles of polyhydroxybutyrate (PHB) in Rhodospirillum rubrum S1 under aerobic chemoheterotrophic conditions'. Applied Microbiology and Biotechnology, 100 (20):8901-8912. |
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| Oliviero G, Brien GL;Watson A;Streubel G;Jerman E;Andrews D;Doyle B;Munawar N;Wynne K;Crean J;Bracken AP;Cagney G (2016) 'Dynamic protein interactions of the Polycomb Repressive Complex 2 during differentiation of pluripotent cells'. Molecular & cellular proteomics : MCP . |
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| Assoc Professor Marguerite Clyne |
| Dunne, C. McDermot, A. Anjan, K. Ryan, A. Reid, C. Clyne, M. (2017) 'Use of Recombinant Mucin Glycoprotein to Assess the Interaction of the Gastric Pathogen Helicobacter pylori with the Secreted Human Mucin MUC5AC'. Bioengineering, 4(2) (34):17. |
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| Assoc Professor John Crean |
| De Chiara, L., Andrews, D., Watson, A., Oliviero, G., Cagney, G. and Crean, J. (2017) 'miR302 regulates SNAI1 expression to control mesangial cell plasticity'. Scientific Reports. |
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| Oliviero G, Brien GL, Waston A, Streubel G, Jerman E, Andrews D, Doyle B, Munawar N, Wynne K, Crean J, Bracken AP, Cagney G. (2016) 'Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells'. Molecular & cellular proteomics : MCP . |
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| Oliviero, G; Brien, GL; Watson, A; Streube, G; Jerman, E; Andrews, D; Doyle, B; Munawar, N; Wynne, K; Crean, J; Bracken, AP; Cagney, G. (2016) 'Dynamic protein interactions of the Polycomb Repressive Complex 2 during differentiation of pluripotent cells'. Molecular and Cellular Proteomics . |
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| Oliviero G, Brien GL;Watson A;Streubel G;Jerman E;Andrews D;Doyle B;Munawar N;Wynne K;Crean J;Bracken AP;Cagney G (2016) 'Dynamic protein interactions of the Polycomb Repressive Complex 2 during differentiation of pluripotent cells'. Molecular & cellular proteomics : MCP . |
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| Professor Michael Duffy |
| Synnott NC, Murray A, McGowan PM, Kiely M, Kiely PA, O'Donovan N, O'Connor DP, Gallagher WM, Crown J, Duffy MJ. (2016) 'Mutant p53: a novel target for the treatment of patients with triple-negative breast cancer?'. International Journal of Cancer . |
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| Professor William Gallagher |
| Li B, Ni Chonghaile T;Fan Y;Madden SF;Klinger R;O'Connor AE;Walsh L;O'Hurley G;Mallya Udupi G;Joseph J;Tarrant F;Conroy E;Gaber A;Chin SF;Bardwell HA;Provenzano E;Crown J;Dubois T;Linn S;Jirstrom K;Caldas C;O'Connor DP;Gallagher WM (2017) 'Therapeutic Rationale to Target Highly Expressed CDK7 Conferring Poor Outcomes in Triple-Negative Breast Cancer'. Cancer Research, 77 (14):3834-3845. |
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| Zuurbier L, Rahman A;Cordes M;Scheick J;Wong TJ;Rustenburg F;Joseph JC;Dynoodt P;Casey R;Drillenburg P;Gerhards M;Barat A;Klinger R;Fender B;O'Connor DP;Betge J;Ebert MP;Gaiser T;Prehn JHM;Griffioen AW;van Grieken NCT;Ylstra B;Byrne AT;van der Flier LG;Gallagher WM;Postel R (2017) 'Apelin: A putative novel predictive biomarker for bevacizumab response in colorectal cancer'. Oncotarget, 8 (26):42949-42961. |
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| Wouters J, Vizoso M;Martinez-Cardus A;Carmona FJ;Govaere O;Laguna T;Joseph J;Dynoodt P;Aura C;Foth M;Cloots R;van den Hurk K;Balint B;Murphy IG;McDermott EW;Sheahan K;Jirstr¿¿m K;Nodin B;Mallya-Udupi G;van den Oord JJ;Gallagher WM;Esteller M (2017) 'Comprehensive DNA methylation study identifies novel progression-related and prognostic markers for cutaneous melanoma'. BMC Medicine, 15 (1). |
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| Moran B, Rahman A;Palonen K;Lanigan FT;Gallagher WM (2017) 'Master Transcriptional Regulators in Cancer: Discovery via Reverse Engineering Approaches and Subsequent Validation'. Cancer Research, 77 (9):2186-2190. |
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| Moran B, Das S;Smeets D;Peutman G;Klinger R;Fender B;Connor K;Ebert M;Gaiser T;Prehn JH;Bacon O;Kay E;Hennessy B;Murphy V;Ylstra B;Lambrechts D;Byrne AT;Gallagher WM;O'Connor DP (2017) 'Assessment of concordance between fresh-frozen and formalin-fixed paraffin embedded tumor DNA methylation using a targeted sequencing approach'. Oncotarget . |
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| Dwane L, Gallagher WM;N¿¿ Chonghaile T;O'Connor DP (2017) 'The Emerging Role of Non-traditional Ubiquitination in Oncogenic Pathways'. The Journal of biological chemistry,292 (9):3543-3551. |
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| O'Farrell AC, Evans R;Silvola JM;Miller IS;Conroy E;Hector S;Cary M;Murray DW;Jarzabek MA;Maratha A;Alamanou M;Udupi GM;Shiels L;Pallaud C;Saraste A;Liljenb¿¿ck H;Jauhiainen M;Oikonen V;Ducret A;Cutler P;McAuliffe FM;Rousseau JA;Lecomte R;Gascon S;Arany Z;Ky B;Force T;Knuuti J;Gallagher WM;Roivainen A;Byrne AT (2017) 'A Novel Positron Emission Tomography (PET) Approach to Monitor Cardiac Metabolic Pathway Remodeling in Response to Sunitinib Malate'. PLoS ONE, 12 (1). |
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| Toomey S, Madden SF;Furney SJ;Fan Y;McCormack M;Stapleton C;Cremona M;Cavalleri GL;Milewska M;Elster N;Carr A;Fay J;Kay EW;Kennedy S;Crown J;Gallagher WM;Hennessy BT;Eustace AJ (2016) 'The impact of ERBB-family germline single nucleotide polymorphisms on survival response to adjuvant trastuzumab treatment in HER2-positive breast cancer'. Oncotarget, 7 (46):75518-75525. |
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| Burke L, Butler CT;Murphy A;Moran B;Gallagher WM;O'Sullivan J;Kennedy BN (2016) 'Evaluation of Cysteinyl Leukotriene Signaling as a Therapeutic Target for Colorectal Cancer'. Frontiers in Cell and Developmental Biology, 4 . |
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| Murphy AG, Casey R;Maguire A;Tosetto M;Butler CT;Conroy E;Reynolds AL;Sheahan K;O'Donoghue D;Gallagher WM;Fennelly D;Kennedy BN;O'Sullivan J (2016) 'Preclinical validation of the small molecule drug quininib as a novel therapeutic for colorectal cancer'.Scientific Reports, 6 . |
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| Mulrane L, Gallagher WM;O'Connor DP (2016) 'Assessment of Significance of Novel Proteins in Breast Cancer Using Tissue Microarray Technology'. Methods in molecular biology (Clifton, N.J.), 1501 :311-325. |
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| Synnott NC, Murray A, McGowan PM, Kiely M, Kiely PA, O'Donovan N, O'Connor DP, Gallagher WM, Crown J, Duffy MJ (2016) 'Mutant p53: A Novel Target for the Treatment of Patients with Triple-Negative Breast Cancer?'. International Journal of Cancer . |
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| Professor Declan Gerard Gilheany |
| Bieszczad, B.; Gilheany, D. G. (2017) 'Highly stereoselective construction of the C2 stereocentre of α-tocopherol (vitamin E) by asymmetric addition of Grignard reagents to ketones'. Organic & biomolecular chemistry, 56 :6483-6492. |
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| Bieszczad, B.; Gilheany, D. G (2017) 'Asymmetric Grignard Synthesis of Tertiary Alcohols through Rational Ligand Design'. Angewandte Chemie International Edition, 56 :4272-4276. |
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| Nikitin, K.; Müller-Bunz, H.; Muldoon, J.; Gilheany, D. G (2017) 'Mysterious Decomposition of Alkoxyphosphonium Chlorides: Postulated Involvement of the HCl2 Anion and Its Capture in the Solid State'. Chemistry - A European Journal, 23 :4794-4802. |
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| Gillick-Healy, M. W.; Jennings, E. V.; Müller-Bunz, H.; Ortin, Y.; Nikitin, K.; Gilheany, D. G (2017) 'Two Independent Orthogonal Stereomutations at a Single Asymmetric Centre: A Narcissistic Couple'. Chemistry - A European Journal, 23 :2332-2339. |
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| Molloy, A. D,; Sánchez-Sanz, G.; Gilheany, D. G. (2016) 'PP-Rotation, P-inversion and Metathesis in Diphosphines studied by DFT Calculations: Comments on Some Literature Conflicts'. Inorganics, 4 :36-46. |
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| Professor Catherine Godson |
| Brennan EP, Cacace A;Godson C (2017) 'Specialized pro-resolving mediators in renal fibrosis'. Molecular Aspects of Medicine . |
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| Brennan E, Wang B;McClelland A;Mohan M;Marai M;Beuscart O;Derouiche S;Gray S;Pickering R;Tikellis C;de Gaetano M;Barry M;Belton O;Ali-Shah ST;Guiry P;Jandeleit-Dahm KA;Cooper ME;Godson C;Kantharidis P (2017) 'Protective Effect of Let-7 miRNA Family in Regulating Inflammation in Diabetes-Associated Atherosclerosis'. Diabetes . |
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| McEvoy C, de Gaetano M;Giffney HE;Bahar B;Cummins EP;Brennan EP;Barry M;Belton O;Godson CG;Murphy EP;Crean D (2017) 'NR4A Receptors Differentially Regulate NF-¿¿B Signaling in Myeloid Cells'. Frontiers in Immunology, 8 . |
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| B¿¿rgeson E, Wallenius V;Syed GH;Darshi M;Lantero Rodriguez J;Bi¿¿rserud C;Ragnmark Ek M;Bj¿¿rklund P;Quiding-J¿¿rbrink M;F¿¿ndriks L;Godson C;Sharma K (2017) 'AICAR ameliorates high-fat diet-associated pathophysiology in mouse and ex vivo models, independent of adiponectin'. Diabetologia, 60 (4):729-739. |
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| Professor Stephen Gordon |
| Correia, C. N., Nalpas, N. C., McLoughlin, K. E., Browne, J. A., Gordon, S. V., MacHugh, D. E., Shaughnessy, R. G. (2017) 'Circulating microRNAs as Potential Biomarkers of Infectious Disease'. Frontiers in Immunology, 8 :118. |
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| Malone, K. M., Farrell, D., Stuber, T. P., Schubert, O. T., Aebersold, R., Robbe-Austerman, S., Gordon, S. V. (2017) 'Updated Reference Genome Sequence and Annotation of Mycobacterium bovis AF2122/97'. Genome Announcements, 5 (14). |
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| Auer, A., Vande Burgt, N. H., Abram, F., Barry, G., Fenton, O., Markey, B. K., Nolan, S., Richards, K., Bolton, D., De Waal, T., Gordon, S. V., O'Flaherty, V., Whyte, P., Zintl, A. (2017) 'Agricultural anaerobic digestion power plants in Ireland and Germany: policy and practice'. Journal of the Science of Food and Agriculture, 97 (3):719-723. |
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| Rahim, Z., Thapa, J., Fukushima, Y., van der Zanden, A. G., Gordon, S. V., Suzuki, Y., Nakajima, C. (2016) 'Tuberculosis Caused by Mycobacterium orygis in Dairy Cattle and Captured Monkeys in Bangladesh: a New Scenario of Tuberculosis in South Asia'.Transboundary and Emerging Diseases . |
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| Avanzi, C., Del-Pozo, J., Benjak, A., Stevenson, K., Simpson, V. R., Busso, P., McLuckie, J., Loiseau, C., Lawton, C., Schoening, J., Shaw, D. J., Piton, J., Vera-Cabrera, L., Velarde-Felix, J. S., McDermott, F., Gordon, S. V., Cole, S. T., Meredith, A. L. (2016) 'Red squirrels in the British Isles are infected with leprosy bacilli'. Science, 354 (6313):744-747. |
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| Malone, K. M., Gordon, S. V. (2016) 'Antibiotic Methylation: A New Mechanism of Antimicrobial Resistance'. Trends in Microbiology, 24 (10):771-2. |
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| Professor Andrew Green |
| Sleven H, Welsh SJ, Yu J, Churchill ME, Wright CF, Henderson A, Horvath R, Rankin J, Vogt J, Magee A, McConnell V, Green A, King MD, Cox H, Armstrong L, Lehman A, Nelson TN; Deciphering Developmental Disorders study.; CAUSES study., Williams J, Clouston P, Hagman J, Németh AH (2016) 'De Novo Mutations in EBF3 Cause a Neurodevelopmental Syndrome'. American Journal of Human Genetics . |
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| MacMahon JM, O'Sullivan MJ, McDermott M, Quinn F, Morris T, Green AJ, Betts DR, O'Connell SM (2016) 'Early Bilateral Gonadoblastoma in a Young Child with Mosaicism for Turner Syndrome and Trisomy 18 with Y'. Hormone Research in Paediatrics . |
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| Carrigan M, Duignan E, Malone CP, Stephenson K, Saad T, McDermott C, Green A, Keegan D, Humphries P, Kenna PF, Farrar GJ. (2016) 'Panel-Based Population Next-Generation Sequencing for Inherited Retinal Degenerations'. Scientific Reports . |
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| Whyte S, Green A, McAllister M, Shipman H. (2016) 'Family Communication in Inherited Cardiovascular Conditions in Ireland'. Journal of Genetic Counseling . |
|
| Dr Jana Haase |
| Haase J, Grudzinska-Goebel J, Müller HK, Münster-Wandowski A, Chow E, Wynne K, Farsi Z, Zander JF, Ahnert-Hilger G. (2017) 'Serotonin Transporter Associated Protein Complexes Are Enriched in Synaptic Vesicle Proteins and Proteins Involved in Energy Metabolism and Ion Homeostasis'. ACS Chemical Neuroscience . |
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| Professor Breandán Kennedy |
| Janina Leyk, Conor Daly, Ulrike Janssen-Bienhold, Breandán Kennedy and Christiane Richter-Landsberg (2017) 'HDAC6 inhibition by tubastatin A is protective against oxidative stress in a photoreceptor cell line and restores visual function in a zebrafish model of inherited blindness'. Cell Death and Disease . |
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| Smith AJ, Carter SP, Kennedy BN. (2017) 'Genome editing: the breakthrough technology for inherited retinal disease?'. Expert Opinion on Biological Therapy . |
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| Merrigan SL Kennedy BN (2017) 'Vitamin D Receptor Agonists Regulate Ocular Developmental Angiogenesis and Modulate Expression of dre-miR-21 and VEGF'. British Journal of Pharmacology . |
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| Clare T. Butler, Alison L. Reynolds, Miriam Tosetto, Eugene T. Dillon, Patrick Guiry, Gerard Cagney, Jacintha O¿Sullivan, Breandán N.Kennedy (2017) 'A Quininib Analogue and Cysteinyl Leukotreine Receptor Antagonist Inhibits VEGF-Independent Angiogenesis and Exerts an Additive Anti-angiogenic Response with Bevacizumab'. Journal of Biological Chemistry . |
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| Jensen VL, Carter S, Sanders AAWM, Li C, Kennedy J, Timbers TA, Cai J, Scheidel N, Kennedy BN, Morin RD, Leroux MR, Blacque OE. (2016) 'Whole-Organism Developmental Expression Profiling Identifies RAB-28 as a Novel Ciliary GTPase Associated with the BBSome and Intraflagellar Transport'. PLoS Genetics . |
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| Tamara Tal; Claire Kilty; Andrew Smith; Carlie LaLone; Breandan Kennedy; Alan Tennant; Catherine McCollum; Maria Bondesson; Thomas Knudsen; Stephanie Padilla; Nicole Kleinstreuer (2016) 'Screening for angiogenic inhibitors in zebrafish to evaluate a predictive model for developmental vascular toxicity'. Reproductive Toxicology . |
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| Glaviano A, Smith AJ, Blanco A, McLoughlin S, Cederlund ML, Heffernan T, Sapetto-Rebow B, Alvarez Y, Yin J, Kennedy BN. (2016) 'A method for isolation of cone photoreceptors from adult zebrafish retinae'. BMC Neuroscience, 7;17(1):71 . |
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| Murphy AG, Casey R, Maguire A, Tosetto M, Butler CT, Conroy E, Reynolds AL, Sheahan K, O'Donoghue D, Gallagher WM, Fennelly D, Kennedy BN, O'Sullivan J. (2016) 'Preclinical validation of the small molecule drug quininib as a novel therapeutic for colorectal cancer'.Scientific Reports . |
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| Burke L, Butler CT, Murphy A, Moran B, Gallagher WM, O'Sullivan J and Kennedy BN (2016) 'Evaluation of Cysteinyl Leukotriene Signaling as a Therapeutic Target for Colorectal Cancer'. Frontiers in Cell and Developmental Biology, 4 :103. |
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| Professor Boris Kholodenko |
| Rauch, N; Rukhlenko, OS; Kolch, W; Kholodenko, BN (2016) 'MAPK kinase signalling dynamics regulate cell fate decisions and drug resistance'. Current Opinion in Structural Biology, 41 :151-158. |
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| Halasz, M; Kholodenko BN; Kolch W; Santra T (2016) 'Integrating network reconstruction with mechanistic modeling to predict cancer therapies'. Science signaling, 9 (455):ra114. |
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| Sanchez-Sanz, G; Tywoniuk, B; Matallanas, D; Romano, D; Nguyen, LK; Kholodenko, BN; Rosta, E; Kolch, W; Buchete, NV (2016) 'SARAH Domain-mediated MST2-RASSF Dimeric Interactions'. PLoS Computational Biology, 12 (10):e1005051. |
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| Fey, D; Matallanas, D; Rauch, J; Rukhlenko, OS; Kholodenko, BN (2016) 'The complexities and versatility of the RAS-to-ERK signalling system in normal and cancer cells'. Seminars in Cell and Developmental Biology, 58 :96-107. |
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| Fey, D; Kuehn, A; Kholodenko, BN (2016) 'On the personalised modelling of cancer signalling'. IFAC Proceedings Volumes (IFAC-PapersOnline), 49 (26):312-317. |
|
| Professor Therese Kinsella |
| Mulvaney EP, Shilling C, Eivers SB, Perry AS, Bjartell A, Kay EW, Watson RW, Kinsella BT. (2016) 'Expression of the TPα and TPβ isoforms of the thromboxane prostanoid receptor (TP) in prostate cancer: clinical significance and diagnostic potential'. Oncotarget, 12256 :1-17. |
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| Professor Ulla Knaus |
| Schwerd T, Bryant RV, Pandey S, Capitani M, Meran L, Cazier J-B, Jung J, Mondal K, Parkes M, Mathew C, Fiedler K, McCarthy DJ, WGS500 Consortium, Oxford IBD cohort study investigators, COLORS in IBD, UK IBD Genetics Consortium, Sullivan P, Rodrigues A, Travis S, Moore C, Sambrook J, Ouwehand WH, Roberts DJ, Danesh J, INTERVAL Study, Russell RK, Wilson DC, Kelsen JR, Cornall R, Denson LA, Kugathasan S, Knaus UG, Goncalves Serra E, Anderson CA, Duerr RH, McGovern DPB, Cho J, Powrie F, Li VSW, Muise AM, Uhlig HH (2017) 'NOX1 loss-of-function genetic variants in patients with inflammatory bowel disease'. Mucosal Immunology . |
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| Parlato M, Charbit-Henrion F, Hayes P, et al. (2017) 'First identification of biallelic inherited DUOX2 inactivating mutations as a cause of very early onset inflammatory bowel disease'.Gastroenterology . |
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| Aviello G, Knaus UG (2017) 'ROS in gastrointestinal inflammation:Rescue or Sabotage?'.British Journal of Pharmacology, 174 (12):1704-1718. |
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| Stenke E, Bourke B, Knaus U (2017) 'Crohn's disease - moving away from the knife'.Frontiers . |
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| Egea J, Fabreget I, Frapart, YM et al. (2017) 'European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)'. Redox Biology . |
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| Zhdanov AV, Aviello G, Knaus UG, Papkovsky DB (2017) 'Cellular ROS imaging with hydro-Cy3 dye is strongly influenced by mitochondrial membrane potential'. Biochimica et biophysica acta, 1861 (2):198-204. |
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| Knaus UG, Hertzberger R, Pircalabioru GG, Yousefi SP, Branco Dos Santos F (2017) 'Pathogen control at the intestinal mucosa - H2O2 to the rescue'. Gut Microbes, 8 (1):67-74. |
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| Alvarez,LA; Kovacic, L; Rodriguez, J; Gosemann, JH; Kubica, M; Pircalabioru, GG; Friedmacher, F; Cean, A; Ghise, A; Sarandan, MB; Puri, P; Daff, S; Plettner, E; von Kriegsheim, A; Bourke, B; Knaus, UG (2016) 'NADPH oxidase-derived H2O2 subverts pathogen signaling by oxidative phosphotyrosine conversion to PB-DOPA'. Proceedings of the National Academy of Sciences of the United States of America, 113 (37):10406-10411. |
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| Professor Sabine Koelle |
| Fernandez-Fuertes, B; Laguna-Barraza, R; Fernandez-Gonzalez, R; Gutierrez-Adan, A; Blanco-Fernandez, A, O`Doherty, A; Di Fenza, M; Kelly AK; Kölle S, Lonergan, P (2017) 'Subfertility in bulls carrying a nonsense mutation in transmembrane protein 95 is due to failure to interact with the oocyte vestments'. Biology of Reproduction, 97 (1):50-60. |
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| Leavy, M; Trottmann M; Liedl, B; Reese, S; Stief, C; Freitag, B; Baugh, J; Spagnoli, G; Koelle S (2017) 'Effects of elevated beta-estradiol levels on the functional morphology of the testis - new insights'. Scientific Reports, 7 (39931):1-11. |
|
| Professor Walter Kolch |
| Fasterius, E., Raso, C., Kennedy, S., Rauch, N., Lundin, P., Kolch, W., Uhlen, M., Al-Khalili Szigyarto, C. (2017) 'A novel RNA sequencing data analysis method for cell line authentication'. PLoS One, 12 (2). |
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| Minke, B., Vandamme, D., Schwarzl, T., Kolch, W., Martin, F. (2017) 'Next Generation RNA Sequencing Analysis Reveals Expression of a Transient EMT Profile During Early Organization of MCF10A Cells in 3D'. Methods Mol Biol, 1501 :233-243. |
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| Santra, T., Roche, S., Conlon, N., O'Donovan, N., Crown, J., O'Connor, R., Kolch, W. (2017) 'Identification of potential new treatment response markers and therapeutic targets using a Gaussian process-based method in lapatinib insensitive breast cancer models'. PLoS One, 12 (5). |
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| Radic-Sarikas, B; Halasz, M; Huber, KVM; Winter, GE; Tsafou, KP; Papamarkou, T; Brunak, S; Kolch, W; Superti-Furga, G (2017) 'Lapatinib potentiates cytotoxicity of YM155 in neuroblastoma via inhibition of the ABCB1 efflux transporter'. Scientific Reports, 7 (1):3091. |
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| Radic-Sarikas, B., Halasz, M., Huber, K. V. M., Winter, G. E., Tsafou, K. P., Papamarkou, T., Brunak, S., Kolch, W., Superti-Furga, G. (2017) 'Lapatinib potentiates cytotoxicity of YM155 in neuroblastoma via inhibition of the ABCB1 efflux transporter'. Sci Rep, 7 (1):3091. |
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| Latosinska, A., Mokou, M., Makridakis, M., Mullen, W., Zoidakis, J., Lygirou, V., Frantzi, M., Katafigiotis, I., Stravodimos, K., Hupe, M. C., Dobrzynski, M., Kolch, W., Merseburger, A. S., Mischak, H., Roubelakis, M. G., Vlahou, A. (2017) 'Proteomics analysis of bladder cancer invasion: Targeting EIF3D for therapeutic intervention'. Oncotarget . |
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| Rauch, J., Kolch, W. (2017) 'Spatial regulation of ARAF controls the MST2-Hippo pathway'.Small GTPases, :1-6. |
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| Duffy, D. J., Krstic, A., Halasz, M., Schwarzl, T., Konietzny, A., Iljin, K., Higgins, D. G., Kolch, W. (2017) 'Retinoic acid and TGF-beta signalling cooperate to overcome MYCN-induced retinoid resistance'. Genome Med, 9 (1):15. |
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| Evans, I. M., Kennedy, S. A., Paliashvili, K., Santra, T., Yamaji, M., Lovering, R. C., Britton, G., Frankel, P., Kolch, W., Zachary, I. C. (2017) 'Vascular Endothelial Growth Factor (VEGF) Promotes Assembly of the p130Cas Interactome to Drive Endothelial Chemotactic Signaling and Angiogenesis'. Mol Cell Proteomics, 16 (2):168-180. |
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| Duffy, DJ; Krstic, A; Halasz, M; Schwarzl, T; Konietzny, A; Iljin, K; Higgins, DG; Kolch, W. (2017) 'Retinoic acid and TGF-β signalling cooperate to overcome MYCN-induced retinoid resistance'. Genome Medicine, 9 (1):15. |
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| Evans, I. M., Kennedy, S. A., Paliashvili, K., Santra, T., Yamaji, M., Lovering, R. C., Britton, G., Frankel, P., Kolch, W., Zachary, I. C. (2016) 'VEGF promotes assembly of the p130Cas interactome to drive endothelial chemotactic signalling and angiogenesis'. Mol Cell Proteomics . |
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| Stanley, E., Delatola, E. I., Nkuipou-Kenfack, E., Spooner, W., Kolch, W., Schanstra, J. P., Mischak, H., Koeck, T. (2016) 'Comparison of different statistical approaches for urinary peptide biomarker detection in the context of coronary artery disease'. BMC Bioinformatics, 17 (1):496. |
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| Rauch, N; Rukhlenko, OS; Kolch, W; Kholodenko, BN (2016) 'MAPK kinase signalling dynamics regulate cell fate decisions and drug resistance'. Current Opinion in Structural Biology, 41 :151-158. |
|
| Rauch, N; Rukhlenko, OS; Kolch, W; Kholodenko, BN (2016) 'MAPK kinase signalling dynamics regulate cell fate decisions and drug resistance'. Current Opinion in Structural Biology, 41 :151-158. |
|
| Halasz, M., Kholodenko, B. N., Kolch, W., Santra, T. (2016) 'Integrating network reconstruction with mechanistic modeling to predict cancer therapies'. Sci Signal, 9 (455). |
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| Iglesias-Martinez, L. F., Kolch, W., Santra, T. (2016) 'BGRMI: A method for inferring gene regulatory networks from time-course gene expression data and its application in breast cancer research'. Sci Rep, 6 :37140. |
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| Halasz M; Kholodenko BN; Kolch W; Santra T (2016) 'Integrating network reconstruction with mechanistic modeling to predict cancer therapies'. Science signaling, 9 (455):ra114. |
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| Halasz, M; Kholodenko BN; Kolch W; Santra T (2016) 'Integrating network reconstruction with mechanistic modeling to predict cancer therapies'. Science signaling, 9 (455):ra114. |
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| Baljuls, A., Dobrzynski, M., Rauch, J., Rauch, N., Kolch, W. (2016) 'Stabilization of C-RAF:KSR1 complex by DiRas3 reduces availability of C-RAF for dimerization with B-RAF'.Cell Signal, 28 (10):1451-62. |
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| Herrero, A., Matallanas, D., Kolch, W. (2016) 'The spatiotemporal regulation of RAS signalling'. Biochem Soc Trans, 44 (5):1517-1522. |
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| Sanchez-Sanz, G., Tywoniuk, B., Matallanas, D., Romano, D., Nguyen, L. K., Kholodenko, B. N., Rosta, E., Kolch, W., Buchete, N. V. (2016) 'SARAH Domain-Mediated MST2-RASSF Dimeric Interactions'. PLoS Comput Biol, 12 (10). |
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| Sanchez-Sanz, G; Tywoniuk, B; Matallanas, D; Romano, D; Nguyen, LK; Kholodenko, BN; Rosta, E; Kolch, W; Buchete, NV (2016) 'SARAH Domain-mediated MST2-RASSF Dimeric Interactions'. PLoS Computational Biology, 12 (10):e1005051. |
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| Dernayka, L., Rauch, N., Jarboui, M. A., Zebisch, A., Texier, Y., Horn, N., Romano, D., Gloeckner, C. J., Kriegsheim, Av, Ueffing, M., Kolch, W., Boldt, K. (2016) 'Autophosphorylation on S614 inhibits the activity and the transforming potential of BRAF'.Cell Signal, 28 (9):1432-9. |
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| Cahill, E. F., Sax, T., Hartmann, I., Haffner, S., Holler, E., Holler, B., Huss, R., Gunther, C., Parolini, O., Kolch, W., Eissner, G. (2016) 'Mesenchymal Stromal Cells Protect Endothelial Cells from Cytotoxic T Lymphocyte-Induced Lysis'. Scand J Immunol, 84 (3):158-64. |
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| Dr Arun Kumar |
| Kumar AHS (2017) 'The Dynamics of Technology in Revolutionizing Education and Research'. Journal of Natural Science, Biology and Medicine, 8 (2):137-138. |
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| Klinkert K, Whelan D, Clover AJ, Leblond AL, Arun HS Kumar, Caplice NM. (2017) 'Selective M2 Macrophage Depletion Leads to Prolonged Inflammation in Surgical Wounds'.European Surgical Research, 58 (3-4):109-120. |
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| Arun HS Kumar (2017) 'Vestibular stimulation for stress management: Attributing the vestibular system networks in potentially regulating physiology beyond body movements and balance'. Journal of Natural Science, Biology and Medicine, 8 (1):1-3. |
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| Professor Carel Le Roux |
| Cohen RV, Luque A, Junqueira S, Ribeiro RA, Le Roux CW. (2017) 'What is the impact on the healthcare system if access to bariatric surgery is delayed?'. Surgery for Obesity and Related Diseases . |
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| Miras AD, le Roux CW. (2017) 'Metabolic Surgery in a Pill'. Cell Metabolism . |
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| Pournaras DJ, Hardwick RH, le Roux CW. (2017) 'Gastrointestinal surgery for obesity and cancer: 2 sides of the same coin'. Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery . |
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| Nielsen MS, Christensen BJ, Ritz C, Rasmussen S, Hansen TT, Bredie WLP, le Roux CW, Sjödin A, Schmidt JB (2017) 'Roux-En-Y Gastric Bypass and Sleeve Gastrectomy Does Not Affect Food Preferences When Assessed by an Ad libitum Buffet Meal'. Obesity Surgery . |
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| Abdelaal M, le Roux CW, Docherty NG. (2017) 'Morbidity and mortality associated with obesity'. Annals of Translational Medicine . |
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| Ooi GJ, Doyle L, Tie T, Wentworth JM, Laurie C, Earnest A, Cowley MA, Sikaris K, le Roux CW, Burton PR, O'Brien PE, Brown WA. (2017) 'Weight loss after laparoscopic adjustable gastric band and resolution of the metabolic syndrome and its components'. International Journal of Obesity . |
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| Miras AD, Herring R, Vusirikala A, Shojaee-Moradi F, Jackson NC, Chandaria S, Jackson SN, Goldstone AP, Hakim N, Patel AG, Umpleby AM, Le Roux CW. (2017) 'Measurement of hepatic insulin sensitivity early after the bypass of the proximal small bowel in humans'.Obesity Science & Practice, 3 (1):95-98. |
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| Neff KJ, Baud G, Raverdy V, Caiazzo R, Verkindt H, Noel C, le Roux CW, Pattou F. (2017) 'Renal Function and Remission of Hypertension After Bariatric Surgery: a 5-Year Prospective Cohort Study'. Obesity Surgery . |
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| Giblin L, McGrath BA, Murray BA, le Roux CW, Docherty NG, McSweeney PL, Kelly AL. (2017) 'Letter to the Editor Regarding Equivalent Increases in Circulating GLP-1 Following Jejunal Delivery of Intact and Hydrolysed Casein: Relevance to Satiety Induction following Bariatric Surgery'. Obesity Surgery . |
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| Hyde KM, Blonde GD, le Roux CW, Spector AC. (2017) 'Liraglutide suppression of caloric intake competes with the intake-promoting effects of a palatable cafeteria diet, but does not impact food or macronutrient selection'. Physiology & behavior . |
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| Laurenius A, Werling M, le Roux CW, Fändriks L, Olbers T. (2017) 'Dumping symptoms is triggered by fat as well as carbohydrates in patients operated with Roux-en-Y gastric bypass'. Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery . |
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| Cohen RV, Luque A, Junqueira S, Ribeiro RA, Le Roux CW. (2017) 'What is the impact on the healthcare system if access to bariatric surgery is delayed?'. Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery . |
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| Mossberg KE, Pournaras DJ, Welbourn R, le Roux CW, Brogren H (2017) 'Differential response of plasma plasminogen activator inhibitor 1 after weight loss surgery in patients with or without type 2 diabetes'. Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery . |
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| Neff KJ, Elliott JA, Corteville C, Abegg K, Boza C, Lutz TA, Docherty NG, le Roux CW. (2017) 'Effect of Roux-en-Y gastric bypass and diet-induced weight loss on diabetic kidney disease in the Zucker diabetic fatty rat'. Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery . |
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| Cohen RV, Pereira TV, Aboud CM, Caravatto PP, Petry TB, Correa JL, Schiavon CA, Correa M, Pompílio CE, Pechy FN, le Roux CW; (2017) 'Microvascular Outcomes after Metabolic Surgery (MOMS) in patients with type 2 diabetes mellitus and class I obesity: rationale and design for a randomised controlled trial'. BMJ Open . |
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| Nair M, le Roux CW, Docherty NG. (2016) 'Measuring changes in renal function after bariatric surgery: Why estimated glomerular filtration rate is not good enough'. Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery . |
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| Murphy CF, le Roux CW. (2016) 'The Neurobiological Impact of Ghrelin Suppression after Oesophagectomy'. International Journal of Molecular Sciences . |
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| O'Neill KN, Finucane FM, le Roux CW, Fitzgerald AP, Kearney PM. (2016) 'Unmet need for bariatric surgery'. Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery . |
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| Nair M, le Roux CW, Docherty NG. (2016) 'Mechanisms underpinning remission of albuminuria following bariatric surgery'. Current Opinion in Endocrinology, Diabetes and Obesity . |
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| Hunt KF, Dunn JT, le Roux CW, Reed LJ, Marsden PK, Patel AG, Amiel SA. (2016) 'Differences in Regional Brain Responses to Food Ingestion After Roux-en-Y Gastric Bypass and the Role of Gut Peptides: A Neuroimaging Study'. Diabetes Care . |
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| Zanchi D, Meyer-Gerspach AC, Suenderhauf C, Janach K, le Roux CW, Haller S, Drewe J, Beglinger C, Wölnerhanssen BK, Borgwardt S. (2016) 'Differential effects of L-tryptophan and L-leucine administration on brain resting state functional networks and plasma hormone levels'. Scientific Reports . |
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| Gorman DM, le Roux CW, Docherty NG. (2016) 'The Effect of Bariatric Surgery on Diabetic Retinopathy: Good, Bad, or Both?'. Diabetes and Metabolism Journal . |
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| Pournaras DJ, Nygren J, Hagström-Toft E, Arner P, le Roux CW, Thorell A. (2016) 'Improved glucose metabolism after gastric bypass: evolution of the paradigm'. Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery . |
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| Professor Patrick Lonergan |
| Byrne CJ, Fair S, English AM, Urh C, Sauerwein H, Crowe MA, Lonergan P, Kenny DA. (2017) 'Effect of breed, plane of nutrition and age on growth, scrotal development, metabolite concentrations and on systemic gonadotropin and testosterone concentrations following a GnRH challenge in young dairy bulls'. Theriogenology, 96 :58-68. |
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| Holden SA, Fernandez-Fuertes B, Murphy EM, Lonergan P, Fair S. (2017) 'Effect of seminal plasma from high- and low-fertility bulls on cauda epididymal sperm function'.Reproduction, Fertility and Development . |
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| Fernandez-Fuertes, B; Laguna-Barraza, R; Fernandez-Gonzalez, R; Gutierrez-Adan, A; Blanco-Fernandez, A, O`Doherty, A; Di Fenza, M; Kelly AK; Kölle S, Lonergan, P (2017) 'Subfertility in bulls carrying a nonsense mutation in transmembrane protein 95 is due to failure to interact with the oocyte vestments'. Biology of Reproduction, 97 (1):50-60. |
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| Parr MH, Scully S, Lonergan P, Evans ACO, Crowe MA, Diskin MG. (2017) 'Establishment of critical timing of progesterone supplementation on corpus luteum and embryo development in beef heifers'. Animal Reproduction Science, 180 :1-9. |
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| Byrne CJ, Fair S, English AM, Holden SA, Dick JR, Lonergan P, Kenny DA. (2017) 'Dietary polyunsaturated fatty acid supplementation of young post-pubertal dairy bulls alters the fatty acid composition of seminal plasma and spermatozoa but has no effect on semen volume or sperm quality'. Theriogenology, 90 :289-300. |
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| Murphy EM, Murphy C, O'Meara C, Dunne G, Eivers B, Lonergan P, Fair S. (2017) 'A comparison of semen diluents on the in vitro and in vivo fertility of liquid bull semen'.Journal of Dairy Science, 100 (2):1541-1554. |
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| Holden SA, Fernandez-Fuertes B, Murphy C, Whelan H, O'Gorman A, Brennan L, Butler ST, Lonergan P, Fair S. (2017) 'Relationship between in vitro sperm functional assessments, seminal plasma composition, and field fertility after AI with either non-sorted or sex-sorted bull semen'. Theriogenology, 87 :221-228. |
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| Fernandez-Fuertes B, Narciandi F, O'Farrelly C, Kelly AK, Fair S, Meade KG, Lonergan P. (2016) 'Cauda Epididymis-Specific Beta-Defensin 126 Promotes Sperm Motility but Not Fertilizing Ability in Cattle'. Biology of Reproduction, 95 (6):122. |
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| Maillo V, Sánchez-Calabuig MJ, Lopera-Vasquez R, Hamdi M, Gutierrez-Adan A, Lonergan P, Rizos D. (2016) 'Oviductal response to gametes and early embryos in mammals'.Reproduction, 52 (4):127-141. |
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| Narciandi F, Fernandez-Fuertes B;Khairulzaman I;Jahns H;King D;Finlay EK;Mok KH;Fair S;Lonergan P;O'Farrelly C;Meade KG (2016) 'Sperm-Coating Beta-Defensin 126 Is a Dissociation-Resistant Dimer Produced by Epididymal Epithelium in the Bovine Reproductive Tract'. Biology of Reproduction . |
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| O'Doherty AM, O'Shea LC, Sandra O, Lonergan P, Fair T, Forde N. (2016) 'Imprinted and DNA methyltransferase gene expression in the endometrium during the pre- and peri-implantation period in cattle'. Reproduction, Fertility and Development . |
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| Pasquariello R, Fernandez-Fuertes B, Strozzi F, Pizzi F, Mazza R, Lonergan P, Gandolfi F, Williams JL. (2016) 'Profiling bovine blastocyst microRNAs using deep sequencing'.Reproduction, Fertility and Development . |
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| Pasquariello R, Fernandez-Fuertes B, Strozzi F, Pizzi F, Mazza R, Lonergan P, Gandolfi F, Williams JL. (2016) 'Profiling bovine blastocyst microRNAs using deep sequencing'.Reproduction, Fertility and Development . |
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| Professor David MacHugh |
| Bryan K., McGivney B.A., Farries G. McGettigan P.A.. McGivney C.L., Gough K.F., MacHugh D.E., Katz L.M., Hill E.W. (2017) 'Equine skeletal muscle adaptations to exercise and training: evidence of differential regulation of autophagosomal and mitochondrial components'. BMC Genomics, 18 (1). |
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| MacHugh D.E., Larson G., Orlando L. (2017) 'Taming the Past: Ancient DNA and the Study of Animal Domestication'. Annual review of animal biosciences, 5 :329-351. |
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| Correia, C. N., Nalpas, N. C., McLoughlin, K. E., Browne, J. A., Gordon, S. V., MacHugh, D. E., Shaughnessy, R. G. (2017) 'Circulating microRNAs as potential biomarkers of infectious disease'. Frontiers in Immunology, 8 :118. |
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| Braud, M., Magee, D. A., Park, S. D., Sonstegard, T. S., Waters, S. M., MacHugh, D. E., Spillane, C. (2017) 'Genome-wide microRNA binding site variation between extinct wild aurochs and modern cattle identifies candidate microRNA-regulated domestication genes'.Frontiers in Genetics, 8 (3):3. |
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| Assoc Professor Patricia Maguire |
| Szklanna PB, Foy M, Wynne K, Byrne D, Maguire PB. (2016) 'Analysis of the proteins associated with platelet detergent resistant membranes'. Proteomics . |
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| Professor Fionnuala McAuliffe |
| Cotter D, Turner M, McAuliffe FM, Higgins MF (2017) 'Medical Students Learning Experience of the labour ward: A qualitative research study'. European Journal of Obstetrics & Gynecology and Reproductive Biology, 206 :204-207. |
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| Fee N, Hartigan L, McAuliffe FM, Higgins MF (2017) 'Education in Sepsis: a review for the clinician of what works, when and how'. Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC . |
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| Ainscough KM, Lindsay KL;O'Sullivan EJ;Gibney ER;McAuliffe FM (2017) 'Behaviour change in overweight and obese pregnancy: a decision tree to support the development of antenatal lifestyle interventions'. Public Health Nutrition, :1-7. |
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| Burke N, Burke G, Breathnach F, McAuliffe F, Morrison JJ, Turner MJ, Dornan S, Higgins JR, Cotter A, Geary M, McParland P, Daly S, Cody F, Dicker P, Tully E, Malone FD, Perinatal Ireland Research Consortium (2017) 'Prediction of Cesarean Delivery in the Term Nulliparous Woman: Results from the Prospective Multi-center Genesis Study'. American Journal of Obstetrics and Gynecology . |
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| Scully, H., Alberdi, G., Segurado, R., McNamara, A., Lindsay, K., Horan, M., Hennessy, E., Gibney, E., McAuliffe, F. (2017) 'Child care exposure influences childhood adiposity at 2 years: Analysis from the ROLO study'. Childhood Obesity, 13 (2):93-101. |
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| O'Farrell AC, Evans R;Silvola JM;Miller IS;Conroy E;Hector S;Cary M;Murray DW;Jarzabek MA;Maratha A;Alamanou M;Udupi GM;Shiels L;Pallaud C;Saraste A;Liljenb¿¿ck H;Jauhiainen M;Oikonen V;Ducret A;Cutler P;McAuliffe FM;Rousseau JA;Lecomte R;Gascon S;Arany Z;Ky B;Force T;Knuuti J;Gallagher WM;Roivainen A;Byrne AT (2017) 'A Novel Positron Emission Tomography (PET) Approach to Monitor Cardiac Metabolic Pathway Remodeling in Response to Sunitinib Malate'. PLoS ONE, 12 (1). |
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| Hehir MP, Breathnach FM, Hogan JL, McAuliffe FM, Geary MP, Daly S, Higgins J, Hunter A, Morrison JJ, Burke G, Mahony R, Dicker P, Tully E, Malone FD (2017) 'Prenatal prediction of significant intertwin birth weight discordance using standard second and third trimester sonographic parameters'. Acta Obstetricia et Gynecologica Scandinavica . |
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| Scully H, Alberdi G, Segurado R, McNamara A, Lindsay K, Horan M, Hennessy E, Gibney E, McAuliffe F (2016) 'Child Care Exposure Influences Childhood Adiposity at 2 Years: Analysis from the ROLO Study'. Childhood Obesity . |
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| Monteith C, Flood K, Mullers S, Unterscheider J, Breathnach F, Daly S, Geary MP, Kennelly MM, McAuliffe FM, O'Donoghue K, Hunter A, Morrison JJ, Burke G, Dicker P, Tully EC, Malone FD (2016) 'Evaluation of normalizing cerebroplacental ratio as a potential predictor for adverse outcome in intrauterine growth restriction: results of the multicenter Prospective Observational Trial to Optimize Pediatric Health in Intrauterine Growth Restriction (PORTO) study'. American Journal of Obstetrics and Gynecology . |
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| Corry E, Mone F, Segurado R, Downey P, McParland P, McAuliffe FM, Mooney EE (2016) 'Placental disease and obnormal umbilical artery Doppler waveforms in trisomy 21 pregnancy: A case-control study'. Placenta . |
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| Cotter D, Turner MJ, McAuliffe FM, Higgins MF (2016) 'Medical Students Learning Experiences of the Labour Ward: A Qualitative Research Study'. Eur J Obstet Gynecol Reprod Biol . |
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| Corry E, Mone F, Segurado R, Downey P, McParland P, McAuliffe FM, Mooney EE (2016) 'Placental disease and abnormal umbilical artery Doppler waveforms in trisomy 21 pregnancy: A case-control study'. Placenta, 47 :24-28. |
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| Alberdi G, McNamara AE, Lindsay KL, Scully HA, Horan MH, Gibney ER, McAuliffe FM. (2016) 'The association between childcare and risk of childhood overweight and obesity in children aged 5 years and under: a systematic review'. European Journal of Pediatrics,175 (10):1277-94. |
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| Corry E, Mone F;Segurado R;Downey P;McParland P;McAuliffe FM;Mooney EE (2016) 'Placental disease and abnormal umbilical artery Doppler waveforms in trisomy 21 pregnancy: A case-control study'. Placenta, 47 :24-28. |
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| Levine TA, Alderdice FA, Grunau RE, McAuliffe FM (2016) 'Prenatal stress and hemodynamics in pregnancy: a systematic review'. Archives of Women's Mental Health . |
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| Alberdi G, McNamara AE;Lindsay KL;Scully HA;Horan MH;Gibney ER;McAuliffe FM (2016) 'The association between childcare and risk of childhood overweight and obesity in children aged 5¿¿years and under: a systematic review'. European Journal of Pediatrics . |
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| Mone F, Mulcahy C, McParland P, McAuliffe F (2016) 'Should we recommend universal aspirin for all pregnant women?'. American Journal of Obstetrics and Gynecology . |
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| Mulcahy CH, Cathcart B, McAuliffe F, McParland P (2016) 'EP01.09: The role of 2D and 3D ultrasound in the prenatal diagnosis of Apert Syndrome'. Ultrasound in Obstetrics and Gynecology . |
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| Crosby DA, Delau D, Brophy C, McAuliffe FM, Mahony R (2016) 'Uptake of the Influenza Vaccination in Pregnancy'. Irish Medical Journal . |
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| Professor Gethin McBean |
| G.J.McBean (2017) 'Cysteine, glutathione and thiol redox balance in astrocytes'.Antioxidants, 6(3) :E62. |
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| Egea, J., Fabregat, I.,¿.. McBean, G.,¿.Daiber, A (151 authors) (2017) 'European contribution to the study of ROS: a summary of the findings and prospects for the future from the COST Action BM1203 (EU-ROS)'. Redox Biology, 13 :94-162. |
|
| Assoc Professor Amanda McCann |
| T Byrne, HG Coleman, JA Cooper, WG McCluggage, A McCann, F Furlong (2017) 'The association between MAD2 and prognosis in cancer: a systematic review and meta-analyses'. Oncotarget . |
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| Matthew Ho Zhi Guang, Amanda McCann, Giada Bianchi, Li Zhang, Paul Dowling, Despina Bazou, Peter O¿Gorman, Kenneth C Anderson (2017) 'Overcoming multiple myeloma drug resistance in the era of cancer omics'. Leukemia & lymphoma, :1-20. |
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| Greville G, McCann A, Rudd PM, Saldova R. (2016) 'Epigenetic Regulation of glycosylation and the impact on chemo-resistance in breast and ovarian cancer'. Epigenetics, 11 (12):845-857. |
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| Professor Grace V T Mulcahy |
| Fu, Y., Browne, J.A., Killick, K, Mulcahy, G. (2017) 'Network Analysis of the Systemic Response to Fasciola hepatica Infection in Sheep Reveals Changes in Fibrosis, Apoptosis, Toll-Like Receptors 3/4, and B Cell Function'. Frontiers in Immunology . |
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| Naranjo Lucena A, Garza Cuartero L, Mulcahy G, Zintl A. (2017) 'The immunological effects of fasciolosis: from bovine tuberculosis to Johne¿s disease'. Veterinary Journal,222 :9-16. |
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| Fu Y, Chryssafidis AL, Browne JA, O'Sullivan J, McGettigan PA, Mulcahy G. (2016) 'Transcriptomic Study on Ovine Immune Responses to Fasciola hepatica Infection'. PLoS Neglected Tropical Diseases . |
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| Dr Peter O'Brien |
| O'Brien, PJ; Efvardsson, A (2017) 'Validation of a Multiparametric, High-Content-Screening Assay for Predictive/Investigative Cytotoxicity: Evidence from Technology Transfer Studies and Literature Review'. Chemical Research in Toxicology . |
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| O'Brien PJ (2017) 'Report and abstracts for 17th Spring ACCP conference with training workshops, and technology exhibits'. Comparative Clinical Pathology . |
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| Dr Eoin O'Cearbhaill |
| Seong KY, Seo MS;Hwang DY;O'Cearbhaill ED;Sreenan S;Karp JM;Yang SY (2017) 'A self-adherent, bullet-shaped microneedle patch for controlled transdermal delivery of insulin'.Journal of controlled release : official journal of the Controlled Release Society . |
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| Dr David O'Connell |
| Kalyani Sanagavarapu, Tanja Weiffert, Niamh Ní Mhurchú, David O¿Connell, Sara Linse (2016) 'Calcium Binding and Disulfide Bonds Regulate the Stability of Secretagogin towards Thermal and Urea Denaturation'. PLoS ONE . |
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| Assoc Professor John O'Connor |
| O'Connor, J.J., O'Boyle, K.M., Lowry, J.P (2017) 'Effects of caffeine and MDMA on real-time stimulated single pulse dopamine release in the rat striatum'. Journal of Neuroscience Methods, 291 (3):1-8. |
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| Fanning, R.A., Sheehan, F., Leyden, C., Duffy, N., Carey, M.F., Campion D.P., O'Connor, J.J. (2017) 'A role for adrenergic receptors in the uterotonic effects of ergometrine in isolated human term non-laboring myometrium'. Anesthesia and Analgesia, 124 (5):1581-1588. |
|
| Professor Stefan Oscarson |
| Bowen, A. and Wear, M.P. and Cordero, R.J.B. and Oscarson, S. and Casadevall, A. (2017) 'A Monoclonal Antibody to Cryptococcus neoformans Glucuronoxylomannan Manifests Hydrolytic Activity for Both Peptides and Polysaccharides'. Journal of Biological Chemistry,292 (2):417-434. |
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| Sankarayanarayanan, N.V. and Strebel, T.R. and Boothello, R.S. and Sheerin, K. and Raghuraman, A. and Sallas, F. and Mosier, P.D. and Watermeyer, N.D. and Oscarson, S. and Desai, U.R. (2017) 'A Hexasaccharide Containing Rare 2-O-Sulfate-Glucuronic Acid Residues Selectively Activates Heparin Cofactor II'. Angewandte Chemie - International Edition, 56 (9):2312-2317. |
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| Sheerin, K. and Guazzelli, L. and Oscarson, S. (2017) 'Large scale synthesis and regioselective protection schemes of ethyl 2-azido-2-deoxy-1-thio-α-D-cellobioside for preparation of heparin thiodisaccharide building blocks'. Carbohydrate Research, 440-441 :16-31. |
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| Bugaytsova, J.A. and Björnham, O. and Chernov, Y.A. and Gideonsson, P. and Henriksson, S. and Mendez, M. and Sjöström, R. and Mahdavi, J. and Shevtsova, A. and Ilver, D. and Moonens, K. and Quintana-Hayashi, M.P. and Moskalenko, R. and Aisenbrey, C. and Bylund, G. and Schmidt, A. and ÿberg, A. and Brännström, K. and Königer, V. and Vikström, S. and Rakhimova, L. and Hofer, A. and ÿgren, J. and Liu, H. and Goldman, M.D. and Whitmire, J.M. and ÿdén, J. and Younson, J. and Kelly, C.G. and Gilman, R.H. and Chowdhury, A. and Mukhopadhyay, A.K. and Nair, G.B. and Papadakos, K.S. and Martinez-Gonzalez, B. and Sgouras, D.N. and Engstrand, L. and Unemo, M. and Danielsson, D. and Suerbaum, S. and Oscarson, S. and Morozova-Roche, L.A. and Olofsson, A. and Gröbner, G. and Holgersson, J. an (2017) 'Helicobacter pylori Adapts to Chronic Infection and Gastric Disease via pH-Responsive BabA-Mediated Adherence'. Cell Host and Microbe, 21 (3):376-389. |
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| Nestor, G. and Anderson, T. and Oscarson, S. and Gronenborn, A.M. (2017) 'Exploiting Uniformly 13C-Labeled Carbohydrates for Probing Carbohydrate-Protein Interactions by NMR Spectroscopy'. Journal of the American Chemical Society, 139 (17):6210-6216. |
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| Sauvageau J, Bhasin M;Guo CX;Adekoya IA;Gray-Owen SD;Oscarson S;Guazzelli L;Cox A (2017) 'Alternate synthesis to d-glycero-¿¿-d-manno-heptose 1,7-biphosphate'.Carbohydrate Research, 450 :38-43. |
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| Touaibia M, Krammer EM;Shiao TC;Yamakawa N;Wang Q;Glinschert A;Papadopoulos A;Mousavifar L;Maes E;Oscarson S;Vergoten G;Lensink MF;Roy R;Bouckaert J (2017) 'Sites for Dynamic Protein-Carbohydrate Interactions of O- and C-Linked Mannosides on the E. coli FimH Adhesin'. Molecules, 22 (7). |
|
| Assoc Professor Francesca Paradisi |
| Planchestainer, M; Contente, M; Cassidy, J; Molinari, F; Tamborini, L; Paradisi, F (2017) 'Continuous flow biocatalysis: production and in-line purification of amines by immobilised transaminase from Halomonas elongata'. Green Chemistry, 19 :372-375. |
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| A. Wester, M. Devocelle, E. A. Tallant, M. C. Chappell, P. E. Gallagher, F. Paradisi (2017) 'Stabilization of Angiotensin-(1-7) by key substitution with a Cyclic Non-natural Amino Acid'. Amino Acids, Peptides and Proteins . |
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| M.L. Contente, M. Planchestainer, F. Molinari, F. Paradisi (2016) 'Stereoelectronic effects in the reaction of aromatic substrates catalysed by Halomonas elongata transaminase and its mutants'. Organic & biomolecular chemistry, 14 :9306-9311. |
|
| Professor Ron Pinhasi |
| Beckers A; Fernandes D; Fina F; Novak M; Abati A; Rostomyan L; Thiry A; Ouafik L; Pasture B; Pinhasi R; Daly AFS (2017) 'Genetic Investigation of a Historical Case of X-Linked Acrogigantism'. Endocrine-Related Cancer . |
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| Jones, ER; Zarina, G; Moiseyev, V; Lightfoot, E; Nigst, PR; Manica, A; Pinhasi, R; Bradley, DG. (2017) 'In review. The Neolithic transition in the Baltic was not driven by admixture with early European farmers'. Current Biology . |
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| Siska, V; Jones, E; Jeon, S; Bhak, Y; Kim, H-M; Cho, YS; Kim, H; Lee, K; Veselovskaya, E; Balueva, T; Gallego Llorente, M; Hofreiter, M; Bradley, D; Eriksson, A; Pinhasi, R; Bhak, J; Manica, A. (2017) 'Genome-wide data from two early Neolithic East Asian individuals dating to 7,700 years ago'. Science Advances . |
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| Skoglund P, Posth C, Sirak K, Spriggs M, Valentin F, Bedford S, Clark GA, Reepmeyer C, Fernandes D, Fu Q, Harney E, Lipson M, Mallick S, Novak M, Rohland N, Stewardson K, Abdullah S, Cox MP, Friedlaender FR, Friedlaender JS, Kivisild T, Koki G, Kusuma P, Merriwether DA, Ricaut F-X, Wee JTS, Patterson N, Krause J, Pinhasi R^, Reich D (2016) 'Ancient genomics and the peopling of the Southwest Pacific'. Nature . |
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| Cheronet O, Finarelli J, Pinhasi R^. (2016) 'Morphological change in cranial shape following the transition to agriculture across western Eurasia'. Scientific Reports . |
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| Cheronet, O; Finarelli, JA; Pinhasi, R (2016) 'Morphological change in cranial shape following the transition to agriculture across western Eurasia'. Scientific Reports, 6 :33316. |
|
| Professor Helen Roche |
| Fallaize R, Carvalho-Wells AL, Tierney AC, Marin C, Kieć-Wilk B, Dembińska-Kieć A, Drevon CA, DeFoort C, Lopez-Miranda J, Risérus U, Saris WH, Blaak EE, Roche HM, Lovegrove JA. (2017) 'APOE genotype influences insulin resistance, apolipoprotein CII and CIII according to plasma fatty acid profile in the Metabolic Syndrome'. Scientific Reports . |
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| Lenighan YM, Nugent AP, Li KF, Brennan L, Walton J, Flynn A, Roche HM, McNulty BA. (2017) 'Processed red meat contribution to dietary patterns and the associated cardio-metabolic outcomes'. British Journal of Nutrition . |
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| Ralston JC, Lyons CL, Kennedy EB, Kirwan AM, Roche HM. (2017) 'Fatty Acids and NLRP3 Inflammasome-Mediated Inflammation in Metabolic Tissues'. Annual Review of Nutrition . |
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| Kirwan AM, Lenighan YM, O'Reilly ME, McGillicuddy FC, Roche HM. (2017) 'Nutritional modulation of metabolic inflammation'. Biochemical Society Transactions . |
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| López-Moreno J, García-Carpintero S, Jimenez-Lucena R, Haro C, Rangel-Zúñiga OA, Blanco-Rojo R, Yubero-Serrano EM, Tinahones FJ, Delgado-Lista J, Pérez-Martínez P, Roche HM, López-Miranda J, Camargo A. (2017) 'Effect of Dietary Lipids on Endotoxemia Influences Postprandial Inflammatory Response'. Journal of Agricultural and Food Chemistry . |
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| Murphy AM, Thomas A, Crinion SJ, Kent BD, Tambuwala MM, Fabre A, Pepin JL, Roche HM, Arnaud C, Ryan S. (2017) 'Intermittent hypoxia in obstructive sleep apnoea mediates insulin resistance through adipose tissue inflammation'. European Respiratory Journal . |
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| Lopez-Moreno J, Quintana-Navarro GM, Camargo A, Jimenez-Lucena R, Delgado-Lista J, Marin C, Tinahones FJ, Striker GE, Roche HM, Perez-Martinez P, Lopez-Miranda J, Yubero-Serrano EM. (2017) 'Dietary fat quantity and quality modifies advanced glycation end products metabolism in patients with metabolic syndrome'. Molecular Nutrition and Food Research . |
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| O'Gorman A, Gibbons H, Ryan MF, Gibney ER, Gibney MJ, Frost GS, Roche HM, Brennan L. (2017) 'Exploring the Links between Diet and Health in an Irish Cohort: A Lipidomic Approach'. Journal of Proteome Research, 16 (3):1280-1287. |
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| McParland, D; Phillips, CM; Brennan, L; Roche, HM and Gormley, IC. (2017) 'Clustering high-dimensional mixed data to uncover sub-phenotypes: joint analysis of phenotypic and genotypic data'. Statistics in Medicine . |
|
| Assoc Professor Brian Rodriguez |
| R. Al-Shammari, M. Manzo, K. Gallo, J. Rice, Brian J. Rodriguez (2017) 'Tunable Wettability of Ferroelectric Lithium Niobate Surfaces: The Role of Engineered Microstructure and Tailored Metallic Nanostructures'. Journal of Physical Chemistry C, 121 (12):6643-6649. |
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| Arwa Bazaid, Sabine M Neumayer, Anna Sorushanova, Jill Guyonnet, Dimitrios Zeugolis and Brian J Rodriguez (2017) 'Non-destructive determination of collagen fibril width in extruded collagen fibres by piezoresponse force microscopy'. Biomedical Physics & Engineering Express . |
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| Liam Collins, Jason Kilpatrick, Sergei Kalinin, Brian J Rodriguez (2017) 'Nanoscale electrical measurements in liquids using AFM - progress and outlook'. Reports on Progress in Physics, ROPP-100858.R1 . |
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| Steven J. Brewer, Samuel C. Williams, Carmen Z. Deng, Aaron B. Naden, Sabine M. Neumayer, Brian J. Rodriguez, Amit Kumar, Nazanin Bassiri-Gharb (2017) 'Functional and structural effects of layer periodicity in chemical solution-deposited Pb(Zr,Ti)O3 thin films'.Journal of the American Ceramic Society . |
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| D. Denning, J. I. Kilpatrick, E. Fukada, N. Zhang, S. Habelitz, A. Fertala, M. D. Gilchrist, Y. Zhang, S. A. M. Tofail, and B. J. Rodriguez (2017) 'Piezoelectric Tensor of Collagen Fibrils Determined at the Nanoscale'. ACS Biomaterials Science & Engineering, 3 (6):929-935. |
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| Ryan, K; Neumayer, SM; Maraka, HVR; Buchete, NV; Kholkin, AL; Rice, JH; Rodriguez, BJ (2017) 'Thermal and aqueous stability improvement of graphene oxide enhanced diphenylalanine nanocomposites'. Science and Technology of Advanced Materials, 18 (1):172-179. |
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| D. Kilinc, A. Blasiak, M. A. Baghban, N. C. Carville, A. Al-Adli, R. M. Al-Shammari, J. H. Rice, G. U. Lee, K. Gallo, and B. J. Rodriguez (2017) 'Charge and topography patterned lithium niobate provides physical cues to fluidically isolated cortical axons'. Applied Physics Letters, 110 :053702. |
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| Professor Denis Shields |
| Wild, Philipp S and Felix, Janine F and Schillert, Arne and Teumer, Alexander and Chen, Ming-Huei and Leening, Maarten JG and V\"olker, Uwe and Gro\ssmann, Vera and Brody, Jennifer A and Irvin, Marguerite R and others (2017) 'Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function'. The Journal of clinical investigation, 127 (5):1798-1812. |
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| Kranjc, Tilen and Dempsey, Eugene and Cagney, Gerard and Nakamura, Nobuhiro and Shields, Denis C and Simpson, Jeremy C (2017) 'Functional characterisation of the YIPF protein family in mammalian cells'. Histochemistry and cell biology, 147 (4):439-451. |
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| Warren, H.R.a b and Evangelou, E.c d and Cabrera, C.P.a b and Gao, H.c e and Ren, M.a b and Mifsud, B.a and Ntalla, I.a and Surendran, P.f and Liu, C.g h i and Cook, J.P.j and Kraja, A.T.k and Drenos, F.l m and Loh, M.c n and Verweij, N.o p q r and Marten, J.s and Karaman, I.c and Lepe, M.P.S.c t and O'Reilly, P.F.u and Knight, J.v and Snieder, H.w and Kato, N.x and He, J.y and Tai, E.S.z aa and Said, M.A.o and Porteous, D.ab and Alver, M.ac and Poulter, N.ad and Farrall, M.ae and Gansevoort, R.T.af and Padmanabhan, S.ag and Mägi, R.ac and Stanton, A.ah and Connell, J.ai and Bakker, S.J.L.aj and Metspalu, A.ac and Shields, D.C.ak and Thom, S.al and Brown, M.a b and Sever, P.al and Esko, T.p ac and Hayward, C.s and Van Der Harst, P.o and Saleheen, D.am an ao and Chowdhury, R.f and Chambers (2017) 'Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk'. Nature Genetics, 49 (3):403-415. |
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| Wild, P.S.a b c and Felix, J.F.d and Schillert, A.e f and Teumer, A.g h and Chen, M.-H.i and Leening, M.J.G.d j and Völker, U.h k and GroÃYmann, V.b and Brody, J.A.l and Irvin, M.R.m and Shah, S.J.n and Pramana, S.o and Lieb, W.p and Schmidt, R.q and Stanton, A.V.r s and Malzahn, D.t and Smith, A.V.u v and Sundström, J.w and Minelli, C.x and Ruggiero, D.y and Lyytikäinen, L.-P.z aa and Tiller, D.ab and Smith, J.G.ac ad ae and Monnereau, C.d af ag and Di Tullio, M.R.ah and Musani, S.K.ai and Morrison, A.C.aj and Pers, T.H.ak al am an and Morley, M.ao and Kleber, M.E.ap and Aragam, J.aq ar and Benjamin, E.J.as at and Bis, J.C.l and Bisping, E.au and Broeckel, U.av and Cheng, S.as aw and Deckers, J.W.j and Del Greco M, F.ax ay and Edelmann, F.az and Fornage, M.ba and Franke, L.bb and Fried (2017) 'Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function'. Journal of Clinical Investigation,127 (5):1798-1812. |
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| Manguy, J.a b c and Jehl, P.b c and Dillon, E.T.a b d and Davey, N.E.b c and Shields, D.C.a b c and Holton, T.A.a b c (2017) 'Peptigram: A Web-Based Application for Peptidomics Data Visualization'. Journal of Proteome Research, 16 (2):712-719. |
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| Professor Jeremy Simpson |
| Long M, Simpson JC (2017) 'Rho GTPases operating at the Golgi complex: Implications for membrane traffic and cancer biology'. Tissue and Cell, 49 :163-169. |
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| Kranjc T, Dempsey E, Cagney G, Nakamura N, Shields DC, Simpson JC. (2017) 'Functional characterisation of the YIPF protein family in mammalian cells'. Histochemistry and Cell Biology, 147 :439-451. |
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| Caruso ME, Jenna S, Baillie DL, Bossé R, Simpson JC, Chevet E, Taouji S. (2017) 'Systematic functional analysis of the Ras GTPase family unveils a conserved network required for anterograde protein trafficking'. Proteomics, 17 . |
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| Bexiga MG, Simpson JC (2016) 'Genome-Wide siRNA Screening Using Forward Transfection: Identification of Modulators of Membrane Trafficking in Mammalian Cells'.Methods in molecular biology (Clifton, N.J.), 1470 :39-48. |
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| Assoc Professor Albert Smolenski |
| Smolenski A (2017) 'Lighting up kinase action in platelets'. Journal of thrombosis and haemostasis : JTH, 15 (7):1484-1486. |
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| Professor Cormac Taylor |
| Cavadas MAS, Cheong A;Taylor CT (2017) 'The regulation of transcriptional repression in hypoxia'. Experimental Cell Research, 356 (2):173-181. |
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| Manresa MC, Taylor CT (2017) 'Hypoxia Inducible Factor (HIF) Hydroxylases as Regulators of Intestinal Epithelial Barrier Function'. Cellular and molecular gastroenterology and hepatology, 3 (3):303-315. |
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| Schaible B, Rodriguez J, Garcia A, von Kriegsheim A, McClean S, Hickey C, Keogh CE, Brown E, Schaffer K, Broquet A, Taylor CT (2017) 'Hypoxia reduces the pathogenicity of Pseudomonas aeruginosa by decreasing the expression of multiple virulence factors'.Journal of Infectious Diseases, 215 (9):1459-1467. |
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| Fagundes RR, Taylor CT (2017) 'Determinants of hypoxia inducible factor (HIF) activity in the intestinal mucosa'. Journal of applied physiology (Bethesda, Md. : 1985) . |
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| McGettrick AF, Corcoran SE;Barry PJ;McFarland J;Cr¿¿s C;Curtis AM;Franklin E;Corr SC;Mok KH;Cummins EP;Taylor CT;O'Neill LA;Nolan DP (2016) 'Trypanosoma brucei metabolite indolepyruvate decreases HIF-1¿¿ and glycolysis in macrophages as a mechanism of innate immune evasion'. Proceedings of the National Academy of Sciences of the United States of America, 113 (48):1-1. |
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| Taylor CT, Doherty G;Fallon PG;Cummins EP (2016) 'Hypoxia-dependent regulation of inflammatory pathways in immune cells'. The Journal of clinical investigation, 126 (10):3716-3724. |
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| Manresa MC, Tambuwala MM;Radhakrishnan P;Harnoss JM;Brown E;Cavadas MA;Keogh CE;Cheong A;Barrett KE;Cummins EP;Schneider M;Taylor CT (2016) 'Hydroxylase inhibition regulates inflammation-induced intestinal fibrosis through the suppression of ERK-mediated TGF-¿¿1 signaling. [corrected]'. American journal of physiology. Gastrointestinal and liver physiology, 311 (6):1-1. |
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| Professor Bill Watson |
| Breen JK, O'Neill A, Murphy L, Fan Y, Boyce S, Fitzgerald N, Dorris E, Brady L, Finn SP, Hayes BD, Treacy A, Barrett C, Abdul Aziz E, Key E, Fitzpatrick JM, Watson RW (2017) 'Investigating the role of the IGF axis as a predictor of biochemical recurrence in prostate cancer patients post-surgery'. Prostate, epublished ahead of print . |
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| Dorris, E; O'Neill, A; Hanrahan, K; Treacy, A; and Watson, RW (2017) 'MARCKS promotes invasion and is associated with biochemical recurrence in prostate cancer'. Oncotarget,epublished ahead of print . |
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| O'Hare, FM; Watson, RW; O'Neill, A; Segurado, R; Sweetman, D; Downey, P; Mooney E; Murphy, J; Donoghue, V; Molloy, EJ (2017) 'Serial cytokine alterations and abnormal neuroimaging in newborn infants with encephalopathy'. Acta Paediatrica Scandinavica,106 (4):561-567. |
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| Walker SM, Knight LA, McCavigan AM, Logan GE, Berge V, Sherif A, Pandha H, Warren AY, Davidson C, Uprichard A, Blayney JK, Price B, Jellema GL, Steele CJ, Svindland A, McDade SS, Eden CG, Foster C, Mills IG, Neal DE, Mason MD, Kay EW, Waugh DJ, Harkin DP, Watson RW, Clarke NW1, Kennedy RD (2017) 'Molecular Subgroup of Primary Prostate Cancer Presenting with Metastatic Biology'. European Urology, published ahead of print . |
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| O'Hare FM, Watson RW, O'Neill A, Segurado R, Sweetman D, Downey P, Mooney E, Murphy J, Donoghue V, Molloy EJ. (2017) 'Serial cytokine alterations and abnormal neuroimaging in newborn infants with encephalopathy'. Acta Paediatrica, International Journal of Paediatrics, 106 (4):561-567. |
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| Hanrahan, O'Neill A, Prencipe M, Bugler J, Murphy L, Fabre A, Puhr M, Culig Z, Murphy K, Watson RW. (2017) 'The role of epithelial-mesenchymal transition drivers ZEB1 and ZEB2 in mediating docetaxel-resistant prostate cancer'. Molecular Oncology, 11 (3):251-265. |
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| Chee YR, Watson RW, McCarthy J, Chughtai JZ, Nölke L, Healy DG (2017) 'High dose statin prophylaxis in cardiopulmonary bypass related surgery: clinical utility'. Journal of Cardiothoracic Surgery, 12 (1):20. |
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| Lundon DJ, Boland A, Prencipe M, Hurley G, O'Neill A, Kay E, Aherne ST, Doolan P, Madden SF, Clynes M, Morrissey C, Fitzpatrick JM, Watson RW. (2017) 'The prognostic utility of the transcription factor SRF in docetaxel-resistant prostate cancer: in-vitro discovery and in-vivo validation'. BMC Cancer, 17 (1):163. |
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| Foley RW, Maweni RM;Gorman L;Murphy K;Lundon DJ;Durkan G;Power R;O'Brien F;O'Malley KJ;Galvin DJ;Murphy TB;Watson RW (2016) 'The ERSPC Risk Calculators Significantly Outperform The PCPT 2.0 In The Prediction Of Prostate Cancer; A Multi-Institutional Study'. BJU International, 118 (5):706-713. |
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| Mulvaney EP, Shilling C, Eivers SB, Perry AS, Bjartell A, Kay EW, Watson RW, Kinsella BT (2016) 'Expression of the TPα and TPβ isoforms of the thromboxane prostanoid receptor (TP) in prostate cancer: clinical significance and diagnostic potential'. Oncotarget, 7 (45):73171-73187. |
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| Professor Gerry Wilson |
| N Nair, AG Wilson, A Barton (2017) 'DNA methylation as a marker of response in rheumatoid arthritis'. Future Rheumatology . |
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| Jani M, Isaacs JD, Morgan AW, Wilson AG, Plant D, Hyrich KL, Chinoy H, Barton A. (2017) 'High frequency of antidrug antibodies and association of random drug levels with efficacy in certolizumab pegol-treated patients with rheumatoid arthritis: results from the BRAGGSS cohort'. Annals of the Rheumatic Diseases, 76 (1):208-213. |
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| Smith, S.L., Plant, D., Eyre, S., Hyrich, K., Morgan, A.W., Wilson, A.G., Isaacs, J.D. and Barton, A. (2017) 'The predictive value of serum S100A9 and response to etanercept is not confirmed in a large UK rheumatoid arthritis cohort'. Rheumatology . |
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| Dr Xiangming Zhu |
| Rao, J; Zhang, G; Zeng, X; Zhu, X (2017) 'Selective Anomeric S-Deacetylation Using Aqueous Sodium Methanethiolate'. Carbohydrate Chemistry, 3 :89-96. |
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| Dada, O; Curran, D; O'Beirne, C; Müller-Bunz, H; Zhu, X; Tacke, M (2017) 'Synthesis and Cytotoxicity Studies of Novel NHC-Gold(I) Pseudohalides and Thiolates'. Journal of Organometallic Chemistry, 840 :30-37. |
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| Walther, W; Dada, O; O¿Beirne, C; Ott, I; Sánchez-Sanz, G; Schmidt, C; Werner, C; Zhu, X; Tacke, M (2017) 'In Vitro and In Vivo Investigations into the Carbene Gold Chloride and Thiolate Anticancer Drug Candidates NHC-AuCl and NHC-AuSR'. Letters in Drug Design and Discovery, 14 (2):125-134. |
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| Tacke, M; Dada, O; O'Beirne, C; Zhu, X; Müller-Bunz, H (2016) 'The Nonisomorphous Crystal Structures of NHC-Au-Cl and NHC-Au-Br (NHC = 1,3-dibenzyl-4,5-diphenyl-imidazol-2-ylidene)'. Acta crystallographica. Section C, Structural chemistry, C72 (11):857-860. |
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| Dr Tadhg Ó'Cróinín |
| Eoin Scanlan, Laura Ardill, Matthew V.X. Whelan, Claire Shortt, Jarleth E. Nally, Billy Bourke and Tadhg O Croinin (2017) 'Relaxation of DNA Supercoiling leads to increased invasion of epithelial cells and protein secretion by Campylobacter jejuni'. Molecular Microbiology, 104 (1):92-104. |
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| Shortt C, Scanlan E, Hilliard A, Cotroneo CE, Bourke B, Ó Cróinín T. (2016) 'DNA Supercoiling Regulates the Motility of Campylobacter jejuni and Is Altered by Growth in the Presence of Chicken Mucus'. mBio, 13 (5):e01227-16-e01227-16. |
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