Biomolecular & Biomedical Science

Book Chapters

Dr Bruce Moran
Das S; Moran B; Perry AS (2018) 'Assessing DNA methylation in cancer stem cells' In: Methods in Molecular Biology.: Humana Press (Springer). , pp.157-178
Dr Tanja Narancic
Wierckx N., Narancic T., Eberlein C., Wei R., Drzyzga O., Magnin A., Ballerstedt H., Kenny S. T., Pollet E., Avérous L., O'Connor K. E., Zimmermann W., Heipieper H. J., Prieto A., Jimenez J., Blank L. M. (2017) 'Plastic biodegradation: challenges and opportunities' In: Handbook of Hydrocarbon and Lipid Microbiology. Consequences of Microbial Interaction with Hydrocarbons, Oils and Lipids. Biodegradation and Bioremediation.Germany: Springer.
Professor Kevin O'Connor
Wierckx N., Narancic T., Eberlein C., Wei R., Drzyzga O., Magnin A., Ballerstedt H., Kenny S. T., Pollet E., Avérous L., O'Connor K. E., Zimmermann W., Heipieper H. J., Prieto A., Jimenez J., Blank L. M. (2017) 'Plastic biodegradation: challenges and opportunities' In: Handbook of Hydrocarbon and Lipid Microbiology. Consequences of Microbial Interaction with Hydrocarbons, Oils and Lipids. Biodegradation and Bioremediation.Germany: Springer.
Dr Jennie Rothwell
Rothwell, Jennie (2017) 'Los documentales de Isabel Coixet: una vocación social' In: Tras las lentes de Isabel Coixet: cine, compromiso y feminismo.Zaragoza, Spain: Prensas de la Universidad de Zaragoza. , pp.379-394

Professor Orina Belton
Bruen R; Curley S; Kajani S; Crean D; O'Reilly ME; Lucitt MB; Godson CG; McGillicuddy FC; Belton O (2017) 'Liraglutide dictates macrophage phenotype in apolipoprotein E mice during early atherosclerosis'. Cardiovascular Diabetology 16 (1).
Assoc Professor Oliver Blacque
Scheidel N; Kennedy J; Blacque OE (2018) 'Endosome maturation factors Rabenosyn-5/VPS45 and caveolin-1 regulate ciliary membrane and polycystin-2 homeostasis'. EMBO Journal 37 (9).
Kazatskaya A; Kuhns S; Lambacher NJ; Kennedy JE; Brear AG; McManus GJ; Sengupta P; Blacque OE (2017) 'Primary cilium formation and ciliary protein trafficking is regulated by the atypical MAP kinase MAPK15 in Caenorhabditis elegans and human cells'. Genetics 207 (4) :1423-1440.
Blacque OE; Scheidel N; Kuhns S (2018) 'Rab GTPases in cilium formation and function'. Small GTPases 9 (43132) :76-94.
Professor Geraldine Butler
Lyden A; Lombardi L; Sire W; Li P; Simpson JC; Butler G; Lee GU (2017) 'Characterization of carboxylate nanoparticle adhesion with the fungal pathogen: Candida albicans'. Nanoscale 9 (41) :15911-15922.
Donovan PD; Gonzalez G; Higgins DG; Butler G; Ito K (2018) 'Identification of fungi in shotgun metagenomics datasets'. PLoS ONE 13 (2).
Turner SA; Ma Q; Ola M; Vicente KMDS; Butler G (2018) 'Dal81 regulates expression of arginine metabolism genes in Candida parapsilosis'. mSphere 3 (2).
Lombardi L; Turner SA; Zhao F; Butler G (2017) 'Gene editing in clinical isolates of Candida parapsilosis using CRISPR/Cas9'. Scientific Reports 7 (1).
Wolfe KH; Butler G (2017) 'Evolution of Mating in the Saccharomycotina'. Annual Review of Microbiology 71 :197-214.
Salazar SB; Wang C; Münsterkötter M; Okamoto M; Takahashi-Nakaguchi A; Chibana H; Lopes MM; Güldener U; Butler G; Mira NP (2018) 'Comparative genomic and transcriptomic analyses unveil novel features of azole resistance and adaptation to the human host in Candida glabrata'. FEMS yeast research 18 (1).
Donovan PD; Holland LM; Lombardi L; Coughlan AY; Higgins DG; Wolfe KH; Butler G (2018) 'TPP riboswitch-dependent regulation of an ancient thiamin transporter in Candida'. PLoS Genetics 14 (5).
Venkatesh A; Murray AL; Boyle AB; Farrington LQ; Maher TJ; Ó'Gaora P; Wolfe KH; O'Brien CE; Butler G (2018) 'Draft genome sequence of a highly heterozygous yeast strain from the Metschnikowia pulcherrima subclade, UCD127'. Genome Announcements 6 (25).
O'Boyle S; Bergin SA; Hussey ÉE; McLaughlin AD; Riddell LR; Byrne KP; Wolfe KH; O'Brien CE; Butler G (2018) 'Draft genome sequence of the yeast Nadsonia starkeyi-henricii UCD142, isolated from forest soil in Ireland'. Genome Announcements 6 (25).
Mullen AA; Lynch CD; Hill SM; Holohan CP; Cróinín T; Wolfe KH; O'Brien CE; Butler G (2018) 'Draft genome sequences of two natural isolates of the yeast Barnettozyma californica from Ireland, UCD09 and UCD89'. Genome Announcements 6 (25).
O’Brien CE; McCarthy CGP; Walshe AE; Shaw DR; Sumski DA; Krassowski T; Fitzpatrick DA; Butler G (2018) 'Genome analysis of the yeast Diutina catenulata, a member of the Debaryomycetaceae/Metschnikowiaceae (CTG-Ser) clade'. PLoS ONE 13 (6).
Dr Gerard Cagney
English JA; Lopez LM; O'Gorman A; Föcking M; Hryniewiecka M; Scaife C; Sabherwal S; Wynne K; Dicker P; Rutten BPF (2018) 'Blood-Based Protein Changes in Childhood Are Associated With Increased Risk for Later Psychotic Disorder: Evidence From a Nested Case-Control Study of the ALSPAC Longitudinal Birth Cohort'. Schizophrenia bulletin 44 (2) :297-306.
Drummond E; Flynn S; Whelan H; Nongonierma AB; Holton TA; Robinson A; Egan T; Cagney G; Shields DC; Gibney ER (2018) 'Casein Hydrolysate with Glycemic Control Properties: Evidence from Cells, Animal Models, and Humans'. Journal of Agricultural and Food Chemistry 66 (17) :4352-4363.
Daly C; Shine L; Heffernan T; Deeti S; Reynolds AL; O'Connor JJ; Dillon ET; Duffy DJ; Kolch W; Cagney G (2017) 'A Brain-Derived Neurotrophic Factor Mimetic Is Sufficient to Restore Cone Photoreceptor Visual Function in an Inherited Blindness Model'. Scientific Reports 7 (1).
Conway E; Jerman E; Healy E; Ito S; Holoch D; Oliviero G; Deevy O; Glancy E; Fitzpatrick DJ; Mucha M (2018) 'A Family of Vertebrate-Specific Polycombs Encoded by the LCOR/LCORL Genes Balance PRC2 Subtype Activities'. Molecular Cell 70 (3) :408-42100000000.
Streubel G; Watson A; Jammula SG; Scelfo A; Fitzpatrick DJ; Oliviero G; McCole R; Conway E; Glancy E; Negri GL (2018) 'The H3K36me2 Methyltransferase Nsd1 Demarcates PRC2-Mediated H3K27me2 and H3K27me3 Domains in Embryonic Stem Cells'. Molecular Cell 70 (2) :371-37900000.
Narancic T; Scollica E; Cagney G; O’Connor KE (2018) 'Three novel proteins co-localise with polyhydroxybutyrate (PHB) granules in Rhodospirillum rubrum S1'. Microbiology (United Kingdom) 164 (4) :625-634.
Farrelly L; Rosato-Siri MV; Föcking M; Codagnone M; Reines A; Dicker P; Wynne K; Farrell M; Cannon M; Cagney G (2017) 'The Effects of Prenatal Iron Deficiency and Risperidone Treatment on the Rat Frontal Cortex: A Proteomic Analysis'. Proteomics 17 (17-18).
Topol A; Zhu S; Hartley BJ; English J; Hauberg ME; Tran N; Rittenhouse CA; Simone A; Ruderfer DM; Johnson J (2017) 'Erratum: Dysregulation of miRNA-9 in a Subset of Schizophrenia Patient-Derived Neural Progenitor Cells (Cell Reports (2016) 15(5) (1024–1036) (S2211124716303965) (10.1016/j.celrep.2016.03.090))'. Cell Reports 20 (10) :2525.
Cotter D; English J; Foecking M; Cannon M; Rutten B; Zammit S; Lewis G; Sabhwerwal S; Lopez L; O’Gorman A (2018) 'O1.1 ALTERED COMPLEMENT PATHWAY PROTEIN EXPRESSION IS ASSOCIATED WITH PSYCHOTIC EXPERIENCES AT AGE 11 WHICH PERSIST AT AGE 18.'. Schizophrenia bulletin 44 (Suppl 1) :S72-S72.
Föcking M; Pollak T; Dicker P; Cagney G; Winter I; Kahn R; McGuire P; Cotter D (2018) 'O1.7. PROTEOMIC ANALYSIS OF BLOOD BASED SAMPLES FROM THE OPTiMiSE (OPTIMIZATION OF TREATMENT AND MANAGEMENT OF SCHIZOPHRENIA IN EUROPE) STUDY POINT TOWARDS COMPLEMENT PATHWAY PROTEIN CHANGES.'. Schizophrenia bulletin 44 (Suppl 1) :S74-S75.
Cotter D; English J; Foecking M; Cannon M; Rutten B; Zammit S; Lewis G; Sabhwerwal S; Lopez L; O’Gorman A (2018) '32.4 ALTERED COMPLEMENT PATHWAY PROTEIN EXPRESSION IS ASSOCIATED WITH PSYCHOTIC EXPERIENCES AT AGE 11 WHICH PERSIST AT AGE 18.'. Schizophrenia bulletin 44 (Suppl 1) :S53-S53.
Willsey AJ; Morris MT; Wang S; Willsey HR; Sun N; Teerikorpi N; Baum TB; Cagney G; Bender KJ; Desai TA (2018) 'The Psychiatric Cell Map Initiative: A Convergent Systems Biological Approach to Illuminating Key Molecular Pathways in Neuropsychiatric Disorders'. Cell 174 (3) :505-520.
Dr Federico Cerrone
Kataria R; Woods T; Casey W; Cerrone F; Davis R; O'Connor K; Ruhal R; Babu R (2018) 'Surfactant-mediated hydrothermal pretreatment of Ryegrass followed by enzymatic saccharification for polyhydroxyalkanoate production'. Industrial Crops and Products 111 :625-632.
Professor Paul Engel
Ibrahim I; Engel PC (2018) 'Halophilic glutamate dehydrogenase activities of halobacterium salinarum strain NRC-36014 cultured in different growth conditions'. Malaysian Journal of Biochemistry and Molecular Biology 21 (1) :14-19.
Professor William Gallagher
Moran B; Silva R; Perry AS; Gallagher WM (2018) 'Epigenetics of malignant melanoma'. Seminars in Cancer Biology 51 :80-88.
Shields S; Conroy E; O'Grady T; McGoldrick A; Connor K; Ward MP; Useckaite Z; Dempsey E; Reilly R; Fan Y (2018) 'BAG3 promotes tumour cell proliferation by regulating EGFR signal transduction pathways in triple negative breast cancer'. Oncotarget 9 (21) :15673-15690.
Synnott NC; Bauer MR; Madden S; Murray A; Klinger R; O'Donovan N; O'Connor D; Gallagher WM; Crown J; Fersht AR (2018) 'Mutant p53 as a therapeutic target for the treatment of triple-negative breast cancer: Preclinical investigation with the anti-p53 drug, PK11007'. Cancer Letters 414 :99-106.
O'Brien KP; Khan S; Gilligan KE; Zafar H; Lalor P; Glynn C; O'Flatharta C; Ingoldsby H; Dockery P; De Bhulbh A (2018) 'Employing mesenchymal stem cells to support tumor-targeted delivery of extracellular vesicle (EV)-encapsulated microRNA-379'. Oncogene 37 (16) :2137-2149.
Prencipe M; Fabre A; Murphy TB; Vargyas E; O'Neill A; Bjartell A; Tasken KA; Grytli HH; Svindland A; Berge V (2018) 'Role of serum response factor expression in prostate cancer biochemical recurrence'. Prostate 78 (10) :724-730.
William Gallagher (2018) 'Translational study reveals a two-faced role of RBM3 in pancreatic cancer and suggests its potential value as a biomarker for improved patient stratification'. Oncotarget 9 (5) :6188-6200.
Elster N; Toomey S; Fan Y; Cremona M; Morgan C; Weiner Gorzel K; Bhreathnach U; Milewska M; Murphy M; Madden S (2018) 'Frequency, impact and a preclinical study of novel ERBB gene family mutations in HER2-positive breast cancer'. Therapeutic Advances in Medical Oncology 10.
Van Dijk E; Biesma HD; Cordes M; Smeets D; Neerincx M; Das S; Eijk PP; Murphy V; Barat A; Bacon O (2018) 'Loss of chromosome 18q11.2-q12.1 is predictive for survival in patients with metastatic colorectal cancer treated with bevacizumab'. Journal of Clinical Oncology 36 (20) :2052-2060.
Dr Jana Haase
Brown E; Mc Veigh CJ; Santos L; Gogarty M; Müller HK; Elfving B; Brayden DJ; Haase J (2018) 'TNFα-dependent anhedonia and upregulation of hippocampal serotonin transporter activity in a mouse model of collagen-induced arthritis'. Neuropharmacology 137 :211-220.
Assoc Professor Caroline Herron
Hughes B; Herron CE (2018) 'Cannabidiol Reverses Deficits in Hippocampal LTP in a Model of Alzheimer’s Disease'. Neurochemical Research :1-11.
Dr David Hughes
Butt J; Jenab M; Willhauck-Fleckenstein M; Michel A; Pawlita M; Kyrø C; Tjønneland A; Boutron-Ruault MC; Carbonnel F; Severi G (2018) 'Prospective evaluation of antibody response to Streptococcus gallolyticus and risk of colorectal cancer'. International Journal of Cancer 143 (2) :245-252.
Lemstrova R; Brynychova V; Hughes DJ; Hlavac V; Dvorak P; Doherty JE; Murray HA; Crockard M; Oliverius M; Hlavsa J (2017) 'Dysregulation of KRAS signaling in pancreatic canceris not associated with KRAS mutations and outcome'. Oncology Letters 14 (5) :5980-5988.
Mohelnikova-Duchonova B; Kocik M; Duchonova B; Brynychova V; Oliverius M; Hlavsa J; Honsova E; Mazanec J; Kala Z; Ojima I (2017) 'Hedgehog pathway overexpression in pancreatic cancer is abrogated by new-generation taxoid SB-T-1216'. Pharmacogenomics Journal 17 (5) :452-460.
Dr Andrew Irving
Kwasnik A; von Kriegsheim A; Irving A; Pennington SR (2018) 'Potential mechanisms of calcium dependent regulation of the mammalian cell cycle revealed by comprehensive unbiased label-free nLC-MS/MS quantitative proteomics'. Journal of Proteomics 170 :151-166.
Dr Cathriona Kearns
Melidou A; Broberg E; Adlhoch C; Snacken R; Penttinen P; Pereyaslov D; Brown C; Redlberger-Fritz M; Popow-Kraupp T; Thomas I (2018) 'Erratum to “Predominance of influenza A(H3N2) virus genetic subclade 3C.2a1 during an early 2016/17 influenza season in Europe – Contribution of surveillance data from World Health Organization (WHO) European region to the WHO vaccine composition consultation for northern hemisphere 2017/18” [Vaccine 35 (2017) 4828–4835] (S0264410X17309659) (10.1016/j.vaccine.2017.07.057))'. Vaccine 36 (19) :2740-2741.
Broberg EK; Waris M; Johansen K; Snacken R; Penttinen P; Trebbien R; Emborg HD; Krause TG; Fischer TK; Kuznetsova N (2018) 'Seasonality and geographical spread of respiratory syncytial virus epidemics in 15 european countries, 2010 to 2016'. Eurosurveillance 23 (5).
Professor Breandán Kennedy
Daly C; Shine L; Heffernan T; Deeti S; Reynolds AL; O'Connor JJ; Dillon ET; Duffy DJ; Kolch W; Cagney G (2017) 'A Brain-Derived Neurotrophic Factor Mimetic Is Sufficient to Restore Cone Photoreceptor Visual Function in an Inherited Blindness Model'. Scientific Reports 7 (1).
Daly C; Ward R; Reynolds AL; Galvin O; Collery RF; Kennedy BN (2018) 'Brain-derived neurotrophic factor as a treatment option for retinal degeneration'. 1074 :465-471.
Ward R; Sundaramurthi H; Di Giacomo V; Kennedy BN (2018) 'Enhancing understanding of the visual cycle by applying CRISPR/Cas9 gene editing in zebrafish'. Frontiers in Cell and Developmental Biology 6 (APR).
Raghupathy RK; Zhang X; Liu F; Alhasani RH; Biswas L; Akhtar S; Pan L; Moens CB; Li W; Liu M (2017) 'Rpgrip1 is required for rod outer segment development and ciliary protein trafficking in zebrafish'. Scientific Reports 7 (1).
Smith AJ; Carter SP; Kennedy BN (2017) 'Genome editing: the breakthrough technology for inherited retinal disease?'. Expert Opinion on Biological Therapy 17 (10) :1245-1254.
Professor Therese Kinsella
Mulvaney EP; O'Meara F; Khan AR; O'Connell DJ; Kinsella BT (2017) 'Identification of α-helix 4 (α4) of Rab11a as a novel Rab11-binding domain (RBD): Interaction of Rab11a with the Prostacyclin Receptor'. Biochimica et Biophysica Acta - Molecular Cell Research 1864 (10) :1819-1832.
O'Sullivan AG; Eivers SB; Mulvaney EP; Kinsella BT (2017) 'Regulated expression of the TPβ isoform of the human T prostanoid receptor by the tumour suppressors FOXP1 and NKX3.1: Implications for the role of thromboxane in prostate cancer'. Biochimica et Biophysica Acta - Molecular Basis of Disease 1863 (12) :3153-3169.
Reid HM; Kinsella BT (2017) 'Corrigendum to “Palmitoylation of the TPβ isoform of the human thromboxane A<inf>2</inf>receptor. Modulation of G protein: Effector coupling and modes of receptor internalization.” [Cell Signal. 19(5) (2007) 1056–1070](S0898656806003226)(10.1016/j.cellsig.2006.12.001)'. Cellular Signalling 38 :238.
Lawler OA; Miggin SM; Kinsella BT (2018) 'Erratum: Protein kinase A-mediated phosphorylation of serine 357 of the mouse prostacyclin receptor regulates its coupling to G<inf>s</inf>-, to G<inf>i</inf>-, and to G<inf>q</inf>-coupled effector signaling (Journal of Biological Chemistry (2001) 276, 36 (33596-33607) DOI: 10.1074/jbc.M104434200)'. Journal of Biological Chemistry 293 (28) :11046.
Adão R; Mendes-Ferreira P; Santos-Ribeiro D; Maia-Rocha C; Pimentel LD; Monteiro-Pinto C; Mulvaney EP; Reid HM; Kinsella BT; Potus F (2018) 'Urocortin-2 improves right ventricular function and attenuates pulmonary arterial hypertension'. Cardiovascular Research 114 (8) :1165-1177.
Dr Rut Klinger
Synnott NC; Bauer MR; Madden S; Murray A; Klinger R; O'Donovan N; O'Connor D; Gallagher WM; Crown J; Fersht AR (2018) 'Mutant p53 as a therapeutic target for the treatment of triple-negative breast cancer: Preclinical investigation with the anti-p53 drug, PK11007'. Cancer Letters 414 :99-106.
Van Dijk E; Biesma HD; Cordes M; Smeets D; Neerincx M; Das S; Eijk PP; Murphy V; Barat A; Bacon O (2018) 'Loss of chromosome 18q11.2-q12.1 is predictive for survival in patients with metastatic colorectal cancer treated with bevacizumab'. Journal of Clinical Oncology 36 (20) :2052-2060.
Kenny C; McDonagh N; Lazaro A; O'Meara E; Klinger R; O'Connor D; Roche F; Hokamp K; O'Sullivan MJ (2018) 'Dysregulated mitogen-activated protein kinase signalling as an oncogenic basis for clear cell sarcoma of the kidney'. Journal of Pathology 244 (3) :334-345.
Dr Lisa Lombardi
Lyden A; Lombardi L; Sire W; Li P; Simpson JC; Butler G; Lee GU (2017) 'Characterization of carboxylate nanoparticle adhesion with the fungal pathogen: Candida albicans'. Nanoscale 9 (41) :15911-15922.
Lombardi L; Turner SA; Zhao F; Butler G (2017) 'Gene editing in clinical isolates of Candida parapsilosis using CRISPR/Cas9'. Scientific Reports 7 (1).
Donovan PD; Holland LM; Lombardi L; Coughlan AY; Higgins DG; Wolfe KH; Butler G (2018) 'TPP riboswitch-dependent regulation of an ancient thiamin transporter in Candida'. PLoS Genetics 14 (5).
Assoc Professor Patricia Maguire
Parsons MEM; McParland D; Szklanna PB; Guang MHZ; O'Connell K; O'Connor HD; McGuigan C; Ainle FN; McCann A; Maguire PB (2017) 'A Protocol for Improved Precision and Increased Confidence in Nanoparticle Tracking Analysis Concentration Measurements between 50 and 120 nm in Biological Fluids'. FRONTIERS IN CARDIOVASCULAR MEDICINE 4.
Monteith C; Egan K; O'Connor H; Maguire P; Kevane B; Szklanna PB; Cooley S; Malone F; Áinle FN (2017) 'Early onset preeclampsia is associated with an elevated mean platelet volume (MPV) and a greater rise in MPV from time of booking compared with pregnant controls: Results of the CAPE study'. Journal of Perinatal Medicine .
Maguire PB; Donlon T; Parsons M; Wynne K; Dillon E; Ní Áinle F; Szklanna PB (2018) 'Proteomic Analysis Reveals a Strong Association of β-Catenin With Cadherin Adherens Junctions in Resting Human Platelets'. Proteomics 18 (9).
Parsons ME; O'Connell K; Allen S; Egan K; Szklanna PB; McGuigan C; Ní Áinle F; Maguire PB (2017) 'Thrombin generation correlates with disease duration in multiple sclerosis (MS): Novel insights into the MS-associated prothrombotic state.'. Multiple sclerosis journal - experimental, translational and clinical 3 (4).
Kevane B; Allen S; Walsh K; Egan K; Maguire PB; Galligan MC; Kenny D; Savage R; Doran E; Lennon (2018) 'Dual endothelin-1 receptor antagonism attenuates platelet-mediated derangements of blood coagulation in Eisenmenger syndrome'. Journal of Thrombosis and Haemostasis 16 (8) :1572-1579.
Parsons MEM; Szklanna PB; Guerrero JA; Wynne K; Dervin F; O'Connell K; Allen S; Egan K; Bennett C; McGuigan C (2018) 'Platelet Releasate Proteome Profiling Reveals a Core Set of Proteins with Low Variance between Healthy Adults'. Proteomics 18 (15).
Szklanna PB; Parsons ME; Wynne K; O'Connor H; Egan K; Allen S; Ní Áinle F; Maguire PB (2018) 'The Platelet Releasate is Altered in Human Pregnancy'. Proteomics - Clinical Applications .
Professor Gethin McBean
Egea J; Fabregat I; Frapart YM; Ghezzi P; Görlach A; Kietzmann T; Kubaichuk K; Knaus UG; Lopez MG; Olaso-Gonzalez G (2018) 'Corrigendum to “European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)” (Redox Biol. (2017) 13 (94–162)(S2213231717303373)(10.1016/j.redox.2017.05.007))'. Redox Biology 14 :694-696.
McBean GJ (2017) 'Cysteine, glutathione, and thiol redox balance in astrocytes'. Antioxidants 6 (3).
Egea J; Fabregat I; Frapart YM; Ghezzi P; Görlach A; Kietzmann T; Kubaichuk K; Knaus UG; Lopez MG; Olaso-Gonzalez G (2017) 'European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)'. Redox Biology 13 :94-162.
Dr Siobhán McClean
O'Connor A; McClean S (2017) 'The role of universal stress proteins in bacterial infections'. Current Medicinal Chemistry 24 (36) :3970-3979.
Roszniowski B; McClean S; Drulis-Kawa Z (2018) 'Burkholderia cenocepacia prophages—prevalence, chromosome location and major genes involved'. Viruses 10 (6).
Reece E; Doyle S; Greally P; Renwick J; McClean S (2018) 'Aspergillus fumigatus inhibits Pseudomonas aeruginosa in co-culture: Implications of a mutually antagonistic relationship on virulence and inflammation in the CF airway'. Frontiers in Microbiology 9 (JUN).
Freschi L; Bertelli C; Jeukens J; Moore MP; Kukavica-Ibrulj I; Emond-Rheault J-G; Hamel J; Fothergill JL; Tucker NP; McClean S (2018) 'Genomic characterisation of an international Pseudomonas aeruginosa reference panel indicates that the two major groups draw upon distinct mobile gene pools.'. FEMS microbiology letters 365 (14).
Assoc Professor Margaret McGee
Dhanda AS; Lulic KT; Vogl AW; Mc Gee MM; Chiu RH; Guttman JA (2018) 'Listeria Membrane Protrusion Collapse: Requirement of Cyclophilin A for Listeria Cell-to-Cell Spreading'. The Journal of Infectious Diseases .
Assoc Professor Tara McMorrow
Obaidi I; Higgins M; Bahar B; Davis JL; McMorrow T (2018) 'Identification of the Multifaceted Chemopreventive Activity of Curcumin Against the Carcinogenic Potential of the Food Additive, KBrO3'. CURRENT PHARMACEUTICAL DESIGN 24 (5) :595-614.
Rodríguez-Ribera L; Slattery C; Mc Morrow T; Marcos R; Pastor S (2017) 'Reactive carbonyl compounds impair wound healing by vimentin collapse and loss of the primary cilium'. Food and Chemical Toxicology 108 :128-138.
Obaidi I; Higgins M; Bahar B; Davis JL; McMorrow T (2018) 'Identification of the multifaceted chemopreventive activity of curcumin against the carcinogenic potential of the food additive, KBrO<inf>3</inf>'. Current Pharmaceutical Design 24 (5) :595-614.
Dr Raul Miranda Caso Luengo
Miranda-CasoLuengo R; Lu J; Williams E; Miranda-CasoLuengo A; Carrington S; Evans ACO; Meijer W (2018) 'Delayed differentiation of vaginal and uterine microbiomes in dairy cows developing postpartum endometritis'. .
Dr Bruce Moran
Moran B; Silva R; Perry AS; Gallagher WM (2018) 'Epigenetics of malignant melanoma'. Seminars in Cancer Biology 51 :80-88.
Professor Cormac Murphy
Sweeney JB; Murphy CD; McDonnell K (2018) 'Development of a bacterial propionate-biosensor for anaerobic digestion monitoring'. Enzyme and Microbial Technology 109 :51-57.
Saccomanno M; Hussain S; O’Connor NK; Beier P; Somlyay M; Konrat R; Murphy CD (2018) 'Biodegradation of pentafluorosulfanyl-substituted aminophenol in Pseudomonas spp'. Biodegradation 29 (3) :259-270.
Rodil A; Bosisio S; Ayoup MS; Quinn L; Cordes DB; Slawin AMZ; Murphy CD; Michel J; O'Hagan D (2018) 'Metabolism and hydrophilicity of the polarised 'Janus face' all-: Cis tetrafluorocyclohexyl ring, a candidate motif for drug discovery'. Chemical Science 9 (11) :3023-3028.
Hussain S; Quinn L; Li J; Casey E; Murphy CD (2017) 'Simultaneous removal of malachite green and hexavalent chromium by Cunninghamella elegans biofilm in a semi-continuous system'. International Biodeterioration and Biodegradation 125 :142-149.
Almahboub SA; Narancic T; Devocelle M; Kenny ST; Palmer-Brown W; Murphy C; Nikodinovic-Runic J; O’Connor KE (2018) 'Biosynthesis of 2-aminooctanoic acid and its use to terminally modify a lactoferricin B peptide derivative for improved antimicrobial activity'. Applied Microbiology and Biotechnology 102 (2) :789-799.
Armstrong D; Kirk SM; Murphy C; Guerriero A; Peruzzini M; Gonsalvi L; Phillips AD (2018) 'Water-Soluble Silver(I) Complexes Featuring the Hemilabile 3,7-Dimethyl-1,3,5-triaza-7-phosphabicyclo[3.3.1]nonane Ligand: Synthesis, Characterization, and Antimicrobial Activity'. Inorganic Chemistry 57 (11) :6309-6323.
Dr Tanja Narancic
Narancic T; Scollica E; Cagney G; O’Connor KE (2018) 'Three novel proteins co-localise with polyhydroxybutyrate (PHB) granules in Rhodospirillum rubrum S1'. Microbiology (United Kingdom) 164 (4) :625-634.
Almahboub SA; Narancic T; Devocelle M; Kenny ST; Palmer-Brown W; Murphy C; Nikodinovic-Runic J; O’Connor KE (2018) 'Biosynthesis of 2-aminooctanoic acid and its use to terminally modify a lactoferricin B peptide derivative for improved antimicrobial activity'. Applied Microbiology and Biotechnology 102 (2) :789-799.
Narancic T; O'Connor KE (2017) 'Design of a tailor-made platform for syngas bioconversion into polyhydroxybutyrate'. Microbial Biotechnology 10 (6) :1300-1301.
Narancic T; O'Connor KE (2017) 'Microbial biotechnology addressing the plastic waste disaster'. Microbial Biotechnology 10 (5) :1232-1235.
Assoc Professor Peadar Ó Gaora
Fatima A; Connaughton RM; Weiser A; Murphy AM; O'Grada C; Ryan M; Brennan L; O'Gaora P; Roche HM (2018) 'Weighted Gene Co-Expression Network Analysis Identifies Gender Specific Modules and Hub Genes Related to Metabolism and Inflammation in Response to an Acute Lipid Challenge'. Molecular Nutrition and Food Research 62 (2).
Venkatesh A; Murray AL; Boyle AB; Farrington LQ; Maher TJ; Ó'Gaora P; Wolfe KH; O'Brien CE; Butler G (2018) 'Draft genome sequence of a highly heterozygous yeast strain from the Metschnikowia pulcherrima subclade, UCD127'. Genome Announcements 6 (25).
Assoc Professor Kathy O'Boyle
O'Connor JJ; O'Boyle KM; Lowry JP (2018) 'Effects of a combination of 3,4-methylenedioxymeth amphetamine and caffeine on real time stimulated dopamine release in the rat striatum: Studies using fast cyclic voltammetry'. Journal of Neuroscience Methods 300 :216-223.
Dr David O'Connell
Mulvaney EP; O'Meara F; Khan AR; O'Connell DJ; Kinsella BT (2017) 'Identification of α-helix 4 (α4) of Rab11a as a novel Rab11-binding domain (RBD): Interaction of Rab11a with the Prostacyclin Receptor'. Biochimica et Biophysica Acta - Molecular Cell Research 1864 (10) :1819-1832.
Mhurchú NN; Zoubak L; McGauran G; Linse S; Yeliseev A; O'Connell DJ (2018) 'Simplifying G Protein-Coupled Receptor Isolation with a Calcium-Dependent Fragment Complementation Affinity System'. Biochemistry 57 (30) :4383-4390.
Professor John O'Connor
Daly C; Shine L; Heffernan T; Deeti S; Reynolds AL; O'Connor JJ; Dillon ET; Duffy DJ; Kolch W; Cagney G (2017) 'A Brain-Derived Neurotrophic Factor Mimetic Is Sufficient to Restore Cone Photoreceptor Visual Function in an Inherited Blindness Model'. Scientific Reports 7 (1).
O'Connor JJ; O'Boyle KM; Lowry JP (2018) 'Effects of a combination of 3,4-methylenedioxymeth amphetamine and caffeine on real time stimulated dopamine release in the rat striatum: Studies using fast cyclic voltammetry'. Journal of Neuroscience Methods 300 :216-223.
Fanning RA; Campion DP; O'Shea M; Carey MF; O'Connor JJ (2017) 'A comparison of the effects of lindane and FeCl<inf>3</inf>/ADP on spontaneous contractions in isolated rat or human term myometrium'. Reproductive Toxicology 74 :164-173.
Lanigan SM; O'Connor JJ (2018) 'The Hypoxia Mimetic Protocatechuic Acid Ethyl Ester Inhibits Synaptic Signaling and Plasticity in the Rat Hippocampus'. Neuroscience 369 :168-182.
Professor Kevin O'Connor
Narancic T; Scollica E; Cagney G; O’Connor KE (2018) 'Three novel proteins co-localise with polyhydroxybutyrate (PHB) granules in Rhodospirillum rubrum S1'. Microbiology (United Kingdom) 164 (4) :625-634.
Kataria R; Woods T; Casey W; Cerrone F; Davis R; O'Connor K; Ruhal R; Babu R (2018) 'Surfactant-mediated hydrothermal pretreatment of Ryegrass followed by enzymatic saccharification for polyhydroxyalkanoate production'. Industrial Crops and Products 111 :625-632.
Almahboub SA; Narancic T; Devocelle M; Kenny ST; Palmer-Brown W; Murphy C; Nikodinovic-Runic J; O’Connor KE (2018) 'Biosynthesis of 2-aminooctanoic acid and its use to terminally modify a lactoferricin B peptide derivative for improved antimicrobial activity'. Applied Microbiology and Biotechnology 102 (2) :789-799.
Narancic T; O'Connor KE (2017) 'Design of a tailor-made platform for syngas bioconversion into polyhydroxybutyrate'. Microbial Biotechnology 10 (6) :1300-1301.
Narancic T; O'Connor KE (2017) 'Microbial biotechnology addressing the plastic waste disaster'. Microbial Biotechnology 10 (5) :1232-1235.
Davis R; Molloy S; Quigley B; Nikodinovic-Runic J; Solano F; O’Connor KE (2018) 'Biocatalytic versatility of engineered and wild-type tyrosinase from R. solanacearum for the synthesis of 4-halocatechols'. Applied Microbiology and Biotechnology 102 (12) :5121-5131.
Veselinović JB; Veselinović AM; Ilic-Tomic T; Davis R; O'Connor K; Pavic A; Nikodinovic-Runic J (2017) 'Potent anti-melanogenic activity and favorable toxicity profile of selected 4-phenyl hydroxycoumarins in the zebrafish model and the computational molecular modeling studies'. Bioorganic and Medicinal Chemistry 25 (24) :6286-6296.
Dr Tadhg Ó'Cróinín
Mullen AA; Lynch CD; Hill SM; Holohan CP; Cróinín T; Wolfe KH; O'Brien CE; Butler G (2018) 'Draft genome sequences of two natural isolates of the yeast Barnettozyma californica from Ireland, UCD09 and UCD89'. Genome Announcements 6 (25).
Dr Niamh O'Sullivan
Byrne DJ; Harmon MJ; Simpson JC; Blackstone C; O'Sullivan NC (2017) 'Roles for the VCP co-factors Npl4 and Ufd1 in neuronal function in Drosophila melanogaster'. Journal of Genetics and Genomics 44 (10) :493-501.
Dr Maria Prencipe
Prencipe M; Fabre A; Murphy TB; Vargyas E; O'Neill A; Bjartell A; Tasken KA; Grytli HH; Svindland A; Berge V (2018) 'Role of serum response factor expression in prostate cancer biochemical recurrence'. Prostate 78 (10) :724-730.
Charmsaz S; Prencipe M; Kiely M; Pidgeon GP; Collins DM (2018) 'Innovative technologies changing cancer treatment'. Cancers 10 (6).
Dr Emmanuel Reynaud
Doyle H; Callaghan E; Reynaud EG (2017) 'Blaschka invertebrate models in Irish institutions'. Journal of the History of Collections 29 (3) :439-450.
Gutierrez-Heredia L; Keogh C; Reynaud EG (2018) 'Assessing the capabilities of additive manufacturing technologies for coral studies, education, and monitoring'. Frontiers in Marine Science 5 (AUG).
Dr Marta Saccomanno
Saccomanno M; Hussain S; O’Connor NK; Beier P; Somlyay M; Konrat R; Murphy CD (2018) 'Biodegradation of pentafluorosulfanyl-substituted aminophenol in Pseudomonas spp'. Biodegradation 29 (3) :259-270.
Dr Craig Slattery
Rodríguez-Ribera L; Slattery C; Mc Morrow T; Marcos R; Pastor S (2017) 'Reactive carbonyl compounds impair wound healing by vimentin collapse and loss of the primary cilium'. Food and Chemical Toxicology 108 :128-138.
Dr Julen Tomás Cortázar
Tomás-Cortázar J; Martín-Ruiz I; Barriales D; Pascual-Itoiz MÁ; de Juan VG; Caro-Maldonado A; Merino N; Marina A; Blanco FJ; Flores JM (2017) 'The immunosuppressive effect of the tick protein, Salp15, is long-lasting and persists in a murine model of hematopoietic transplant'. Scientific Reports 7 (1).
Dr Yan Yan
Lara S; Perez-Potti A; Herda LM; Adumeau L; Dawson KA; Yan Y (2018) 'Differential Recognition of Nanoparticle Protein Corona and Modified Low-Density Lipoprotein by Macrophage Receptor with Collagenous Structure'. ACS Nano 12 (5) :4930-4937.

Professor Orina Belton
Bruen R; Curley S; Kajani S; O'reilly M; Hogan A; O'shea D; Mcgillicuddy F; Belton O (2018) GLUCAGON-LIKE PEPTIDE 1 RECEPTOR AGONIST LIRAGLUTIDE IMPACTS IMMUNE CELL PHENOTYPES IN APOLIPOPROTEIN E DEFICIENT MICE DURING PROGRESSION AND REGRESSION OF PRE-ESTABLISHED ATHEROSCLEROSIS In: ATHEROSCLEROSIS
Fitzsimons S; Mahon N; Belton O (2018) CIRCULATING URINARY EXTRACELLULAR VESICLE SECRETION AND MICRORNA-155 EXPRESSION ARE ALTERED IN PATIENTS WITH SEVERE CORONARY ARTERY DISEASE In: ATHEROSCLEROSIS
Dr Gerard Cagney
Ardill L; Cagney G; Ó'Cróinín T (2018) An investigation into the link between DNA supercoiling and protein secretion in Campylobacter jejuni In: Microbes and Mucosal Surfaces
Professor William Gallagher
Gallagher W; Ainscow EK; Leishman A; Sullivan E; Li B; Peal A; Clark C; Thompson S; Ali S; Coombes RC (2018) CT7001: An orally bioavailable CDK7 inhibitor is a potential therapy for breast, small-cell lung and haematological cancers In: AACR Annual Meeting 2018; April 14-18, 2018; Chicago, IL, Chicago, IL
Das S; Naicker K; Klinger R; Fan Y; Mallya G; Ponten F; Jirström K; O'Sullivan J; Gallagher W; Brennan D (2018) The loss of SATB2 promotes ulcerative colitis-related colon cancer progression through altered localized inflammatory response In: AACR Annual Meeting 2018; April 14-18, 2018; Chicago, IL, Chicago IL
Lynch SM; O'Neill KM; McKenna MM; Walsh CP; Watson W; Gallagher W; McKenna DJ (2018) Abstract 4418: Investigation of miR-205 expression and its methylation status in prostate cancer In: AACR Annual Meeting 2018; April 14-18, 2018; Chicago, IL, Chicago IL
Barron S; Jirstrom K; Nodin B; Jernstrom H; Ingvar C; Moran B; Wang C-JA; Loughman T; Fender B; Dynoodt P (2017) Prognostic value of master transcriptional regulators (MTRs) in early stage breast cancer In: ANNALS OF ONCOLOGY
Dr Antonio Garzon Vico
Garzon Vico A; Gibbons P; Rosier J; McNamara P (2018) The Impact of First-Hand and Others' Major Failure and Success Experience On Drug Development In: Academy of Management Proceedings, Chicago, Michigan, USA
Professor Breandán Kennedy
Sundaramurthi H; Rueckert H; Moran A; Reynolds A; Kennedy B (2018) Can histone deacetylase inhibitors uncover novel therapeutic agents for inherited retinal dystrophies In: Pharmacology 2017, London
comer S; mcloughlin S; Galvin O; Keoghegan C; Kennedy B; Daly C (2018) Promoting scientific enquiry and inherited disease awareness: UCD Science inherited blindness summer school In: Pharmacology 2017
Assoc Professor Patricia Maguire
Mone F; Szklanna P; Verjans M; Mulcahy C; McParland P; Parsons M; NiAilne F; Maguire P; McAuliffe FM (2018) The relationship between placental extracellular vesicle production with pre-eclampsia screening measures, aspirin use and the development of severe placental disease In: BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
Professor Wim Meijer
O'Sullivan J; Bedri Z; Corkery A; Deering L; Demeter K; Meijer W; Masterson B; O'Hare G (2018) Integrated modelling of urban, rural and coastal domains for bathing water quality prediction – Smart Coasts and Acclimatize Projects In: CIWEM UDG 2018
Professor John O'Connor
Campion D; Fanning R; Carey M; O'Connor J (2018) Effects of lindane and FeCl3/ADP on spontaneous contractions in isolated pregnant rat and human term non-labouring myometrium In: Pharmacology 2017, London, UK
Dr Tadhg Ó'Cróinín
Ardill L; Cagney G; Ó'Cróinín T (2018) An investigation into the link between DNA supercoiling and protein secretion in Campylobacter jejuni In: Microbes and Mucosal Surfaces
Whelan M; Simpson J; Ó'Cróinín T (2018) An imaging based investigation into the role of relaxation of negative DNA Supercoiling in Invasion of human epithelial cells and biofilm formation in Campylobacter jejuni In: Microbes and Mucosal Surfaces

UCD Biomolecular & Biomedical Science

UCD School of Biomolecular & Biomedical Science - Research Publications 2017/18

UCD Biomolecular & Biomedical Science

UCD School of Biomolecular & Biomedical Science - Research Publications 2017/18

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