Below is the list of research publications for the School of Biomolecular and Biomedical Science in the academic year 2022/23.
Dr Gary Brennan | |
Quinlan, S., Henke, C., Brennan, G. P., Henshall, D. C., & Jimenez-Mateos, E. M. (2023). Detection of MicroRNAs in Brain Slices Using In Situ Hybridization. In Methods in Molecular Biology (Vol. 2595, pp. 93-100). doi:10.1007/978-1-0716-2823-2_6 |
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Dr Hilary Cassidy | |
Gaspar, V. I., Cassidy, H., Slattery, C., Connolly, L., & McMorrow, T. (2023). In vitro-, ecological-, murine, and human models for examining the effects of EDCs. In Environmental Contaminants and Endocrine Health (pp. 45-53). doi:10.1016/B978-0-12-824464-7.00024-6 |
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Ms Harsha Ganesan | |
Shruthi, N. R., Jain, M. S., Ganesan, H., Banerjee, A., Zhang, H., Sun, X. F., & Pathak, S. (2023). Drug Repurposing in Cancer. In Drug Repurposing for Emerging Infectious Diseases and Cancer (pp. 159-179). doi:10.1007/978-981-19-5399-6_8 |
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Assoc Professor Carmel Hensey | |
Azzi, A. M., Bartoli, G., Boscoboinik, D., Hensey, C., & Szewczyk, A. (2023). a-Tocopherol and Protein Kinase C Regulation of Intracellular Signaling. In Vitamin E in Health and Disease (pp. 371-384). doi:10.1201/9781003418160-35 |
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Dr Mohd Faheem Khan | |
Khan, M. F., & Murphy, C. D. M. (2023). Environmental Remediation by Novel Nanomaterials and Fungi with High-degradation Capacity of Hazardous Contaminants. In Bio and Nanoremediation of Hazardous Environmental Pollutants (pp. 283-310). doi:10.1201/9781003052982-14 |
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Luqueño, F. F., López-Valdez, F., & Pérez, G. M. (n.d.). Bio and Nanoremediation of Hazardous Environmental Pollutants. CRC Press. doi:10.1201/9781003052982 |
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Professor Patricia Maguire | |
Szklanna, P. B., Weiss, L., Namee, B. M., Faryal, R., Kevane, B., Áinle, F. N., & Maguire, P. B. (2023). AI in Haematology. In AI in Clinical Medicine: A Practical Guide for Healthcare Professionals (pp. 184-191). doi:10.1002/9781119790686.ch18 |
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Assoc Professor Tara McMorrow | |
Gaspar, V. I., Cassidy, H., Slattery, C., Connolly, L., & McMorrow, T. (2023). In vitro-, ecological-, murine, and human models for examining the effects of EDCs. In Environmental Contaminants and Endocrine Health (pp. 45-53). doi:10.1016/B978-0-12-824464-7.00024-6 |
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Dr Jennifer Mitchell | |
Mitchell, J. (2023). ISBN: 978-1-910963-67-8. In L. Padden, D. Elliot, J. Tonge, & L. Hyland (Eds.), Learning from UDL Leaders: UCD University for All Faculty Partner Case Studies. Ireland: UCD Access & Lifelong Learning. |
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Professor Cormac Murphy | |
Khan, M. F., & Murphy, C. D. M. (2023). Environmental Remediation by Novel Nanomaterials and Fungi with High-degradation Capacity of Hazardous Contaminants. In Bio and Nanoremediation of Hazardous Environmental Pollutants (pp. 283-310). doi:10.1201/9781003052982-14 |
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Luqueño, F. F., López-Valdez, F., & Pérez, G. M. (n.d.). Bio and Nanoremediation of Hazardous Environmental Pollutants. CRC Press. doi:10.1201/9781003052982 |
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Dr Emmanuel Reynaud | |
Walter, A., Slezak, P., Mueller, R., & Kerckhofs, G. (Eds.) (2023). Bioimaging in Tissue Engineering and Regeneration. In . Springer International Publishing. doi:10.1007/978-3-030-85569-7 |
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Dr Craig Slattery | |
Gaspar, V. I., Cassidy, H., Slattery, C., Connolly, L., & McMorrow, T. (2023). In vitro-, ecological-, murine, and human models for examining the effects of EDCs. In Environmental Contaminants and Endocrine Health (pp. 45-53). doi:10.1016/B978-0-12-824464-7.00024-6 |
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Dr Luisa Weiss | |
Szklanna, P. B., Weiss, L., Namee, B. M., Faryal, R., Kevane, B., Áinle, F. N., & Maguire, P. B. (2023). AI in Haematology. In AI in Clinical Medicine: A Practical Guide for Healthcare Professionals (pp. 184-191). doi:10.1002/9781119790686.ch18 |
Dr Derek Costello | |
Galvin, D., Woods, M., McCormack, C., Paulose, A., Creaven, B., & Costello, D. (2023). A novel therapy for the treatment of TLR mediated neuroinflammation. In Brain and Neuroscience Advances Vol. 7 (pp. 156). Brighton, UK: SAGE Publishing. doi:10.1177/23982128231180246 |
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Ralph, A., Fitzsimons, A., Galvin, D., Creaven, B., Blacque, O., & Costello, D. (2023). Investigating a novel coumarin-derivative in models of Alzheimer’s disease in vitro and in vivo. In Brain and Neuroscience Advances Vol. 7 (pp. 157). Brighton, UK: SAGE Publishing. doi:10.1177/2398212823118024 |
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Abstract (2019). In Brain and Neuroscience Advances Vol. 3. SAGE Publications. doi:10.1177/2398212819855490 |
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Dr Jessica Davis | |
Clerkin, S., Wychowaniec, J. K., Singh, K., Davis, J. L., Treacy, N. J., Krupa, I., et al. (2023). UTILITY OF GELATIN METHACRYLOYL (GELMA) HYDROGELS AS TUNEABLE BIOPHYSICAL SCAFFOLDS FOR THE DERIVATION OF HIPSC-DERIVED KIDNEY ORGANOIDS. In TISSUE ENGINEERING PART A Vol. 29 (pp. 1523). |
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Dr Joanna Drabinska | |
Duggan, N., O’Donoghue, É., Drabinksa, J., Schaffer, K., & McClean, S. (2023). P234 Investigating the role of hypoxia in driving the adaptation of Mycobacterium abscessus infection in cystic fibrosis. In Journal of Cystic Fibrosis Vol. 22 (pp. S137). Elsevier BV. doi:10.1016/s1569-1993(23)00606-9 |
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Drabinska, J., Mazhova, A., Duggan, N., & McClean, S. (2023). WS07.03 A long-term study of Pseudomonas aeruginosa early patient isolate adaptation to the hypoxic environment. In Journal of Cystic Fibrosis Vol. 22 (pp. S14-S15). Elsevier BV. doi:10.1016/s1569-1993(23)00225-4 |
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Assoc Professor Caroline Herron | |
Gil, B., & Herron, C. (2023). CANNABIDIOLIC ACID TREATMENT REVERSES DEFICITS IN SYNAPTIC PLASTICITY IN HIPPOCAMPAL SLICES FROM THE APP/PS1 MOUSE MODEL OF ALZHEIMER'S DISEASE. In 32nd Annual Symposium on the Cannabinoids, International Cannabinoid Research Society, Research Triangle Park, NC, USA Vol. 32 (pp. 149). Galway, Ireland: International Cannabinoid Research Society. |
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Professor Breandán Kennedy | |
Brugnera, M., Messina, F., Reynolds, A., O'Reilly, N., Kalesnykas, G., Herrero-Vanrell, R., et al. (2022). Brain-derived neurotrophic factor-mimetic compounds in biodegradable microspheres as novel neuroprotective approaches for retinal diseases. In Acta Ophthalmologica Vol. 100. Wiley. doi:10.1111/j.1755-3768.2022.0369 |
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Pendino, M., Garcia Mulero, S., Sanz Pamplona, R., Marcone, S., O'Connell, F., O'Sullivan, J., et al. (2023). Evaluating cannabinoid receptors as a therapeutic target for uveal melanoma. In BRITISH JOURNAL OF PHARMACOLOGY Vol. 180 (pp. 492-493). |
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Professor Patricia Maguire | |
Kelliher, S., Ní Áinle, F., Weiss, L., Gamba, S., Fouhy, E., Marchetti, M., et al. (2022). Analysis of the Platelet Proteome Reveals Insights into the Pro-Inflammatory and Pro-Thrombotic State Associated with the Philadelphia Chromosome-Negative Myeloproliferative Neoplasms. In Blood Vol. 140 (pp. 2654-2655). American Society of Hematology. doi:10.1182/blood-2022-167119 |
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Assoc Professor Siobhán McClean | |
Duggan, N., O’Donoghue, É., Drabinksa, J., Schaffer, K., & McClean, S. (2023). P234 Investigating the role of hypoxia in driving the adaptation of Mycobacterium abscessus infection in cystic fibrosis. In Journal of Cystic Fibrosis Vol. 22 (pp. S137). Elsevier BV. doi:10.1016/s1569-1993(23)00606-9 |
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Drabinska, J., Mazhova, A., Duggan, N., & McClean, S. (2023). WS07.03 A long-term study of Pseudomonas aeruginosa early patient isolate adaptation to the hypoxic environment. In Journal of Cystic Fibrosis Vol. 22 (pp. S14-S15). Elsevier BV. doi:10.1016/s1569-1993(23)00225-4 |
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Carey, C., Drabinsak, J., & McClean, S. (2023). The effect of hypoxic conditions on Burkholderia cenocepacia clinical isolates from individuals with cystic fibrosis. In European Cystic Fibrosis Society Conference Vol. Journal of Cystic Fibrosis 22 (2023): S139-S140.. |
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Assoc Professor Tadhg Ó'Cróinín | |
Whelan, M., Simpson, J., & Ó'Cróinín, T. (2023). A DNA Supercoiling - induced secretory phenotype enhances tight junction disruption, adherens junction breakdown and actin remodelling in 3D intestinal Spheroids for Campylobacter jejuni. In Annual Conference Microbiology Society 2023. |
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Carney, G., Clyne, M., & Ó'Cróinín, T. (2023). Aerobic acclimation and acquisition of fluoroquinolone resistance have a similar impact on the phenotype of Campylobacter isolates. In Microbiology Society Annual Conference 2023. |
Dr Hilary Cassidy | |
Iban˜ez Gaspar, V., Cassidy, H., Slattery, C., Connolly, L., & McMorrow, T. (2023). Environmental Contaminants and Endocrine Health (1st edition ed.). O. Carnevali, & G. Hardiman (Eds.), London, United Kingdom: Elsevier Science Publishing Co Inc. |
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Assoc Professor Tara McMorrow | |
Iban˜ez Gaspar, V., Cassidy, H., Slattery, C., Connolly, L., & McMorrow, T. (2023). Environmental Contaminants and Endocrine Health (1st edition ed.). O. Carnevali, & G. Hardiman (Eds.), London, United Kingdom: Elsevier Science Publishing Co Inc. |
Professor Oliver Blacque | |
Chrystal, P. W., Lambacher, N. J., Doucette, L. P., Bellingham, J., Schiff, E. R., Noel, N. C. L., et al. (2022). The inner junction protein CFAP20 functions in motile and non-motile cilia and is critical for vision. Nature Communications, 13(1). doi:10.1038/s41467-022-33820-w |
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Dr Gary Brennan | |
Leavy, A., Brennan, G. P., & Jimenez-Mateos, E. M. (2022). MicroRNA Profiling Shows a Time-Dependent Regulation within the First 2 Months Post-Birth and after Mild Neonatal Hypoxia in the Hippocampus from Mice. Biomedicines, 10(11). doi:10.3390/biomedicines10112740 |
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Engel, T., Brennan, G. P., & Soreq, H. (2022). Editorial: The molecular mechanisms of epilepsy and potential therapeutics. Frontiers in Molecular Neuroscience, 15. doi:10.3389/fnmol.2022.1064121 |
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Brindley, E., Heiland, M., Mooney, C., Diviney, M., Mamad, O., Hill, T. D. M., et al. (2023). Brain cell-specific origin of circulating microRNA biomarkers in experimental temporal lobe epilepsy. Frontiers in Molecular Neuroscience, 16. doi:10.3389/fnmol.2023.1230942 |
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Dr Kieran Brennan | |
Kulka, M., Brennan, K., & Gee, M. M. (2022). Investigation of canine extracellular vesicles in diffuse large B-cell lymphomas. PLoS ONE, 17(9 September). doi:10.1371/journal.pone.0274261 |
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Brennan, K., Iversen, K. F., Blanco-Fernández, A., Lund, T., Plesner, T., & Mc Gee, M. M. (2022). Extracellular Vesicles Isolated from Plasma of Multiple Myeloma Patients Treated with Daratumumab Express CD38, PD-L1, and the Complement Inhibitory Proteins CD55 and CD59. Cells, 11(21). doi:10.3390/cells11213365 |
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Gorry, R., Brennan, K., Lavin, P. T. M., Sheridan, R., & Mc Gee, M. M. (2023). Phosphorylation of the prolyl isomerase Cyclophilin A regulates its localisation and release from the centrosome during mitosis. Cell Cycle, 22(8), 951-966. doi:10.1080/15384101.2023.2167430 |
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Gorry, R. L., Brennan, K., Lavin, P. T. M., Mazurski, T., Mary, C., Matallanas, D., et al. (2023). Cyclophilin A Isomerisation of Septin 2 Mediates Abscission during Cytokinesis. International Journal of Molecular Sciences, 24(13). doi:10.3390/ijms241311084 |
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Professor Geraldine Butler | |
Bergin, S. A., Zhao, F., Ryan, A. P., Müller, C. A., Nieduszynski, C. A., Zhai, B., et al. (2022). Systematic Analysis of Copy Number Variations in the Pathogenic Yeast Candida parapsilosis Identifies a Gene Amplification in RTA3 That is Associated with Drug Resistance. mBio, 13(5). doi:10.1128/mbio.01777-22 |
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Igharo, B., Byrne, K. P., Ghnewa, H., Davey, R. P., Fubara, A., Welc, J., et al. (2022). Draft Genome Sequence of the Yeast Torulaspora quercuum Strain UCD657, Isolated from Soil in Ireland. Microbiology Resource Announcements, 11(11). doi:10.1128/mra.00952-22 |
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Don, A., Byrne, K. P., Alqaderi, F., Mazhova, A., Chaney, B. O. L., Redmond, S., et al. (2022). Draft Genome Sequence of the Yeast Blastobotrys aristata Strain UCD613, Isolated from Soil in Ireland. Microbiology Resource Announcements, 11(11). doi:10.1128/mra.00957-22 |
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Lombardi, L., Bergin, S. A., Ryan, A., Zuniga-Soto, E., & Butler, G. (2022). CRISPR-Cas9 Editing Induces Loss of Heterozygosity in the Pathogenic Yeast Candida parapsilosis. mSphere, 7(6). doi:10.1128/msphere.00393-22 |
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Branco, J., Ryan, A. P., Pinto e Silva, A., Butler, G., Miranda, I. M., & Rodrigues, A. G. (2022). Clinical azole cross-resistance in Candida parapsilosis is related to a novel MRR1 gain-of-function mutation. Clinical Microbiology and Infection, 28(12), 1655.e5-1655.e8. doi:10.1016/j.cmi.2022.08.014 |
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Nourrisson, C., Moniot, M., Lavergne, R. A., Robert, E., Bonnin, V., Hagen, F., et al. (2023). Acquired fluconazole resistance and genetic clustering in Diutina (Candida) catenulata from clinical samples. Clinical Microbiology and Infection, 29(2), 257.e7-257.e11. doi:10.1016/j.cmi.2022.09.021 |
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Barsh, G. S., Butler, G., Copenhaver, G. P., Crosson, S., Søgaard-Andersen, L., & Stukenbrock, E. H. (2023). Endless microbes most beautiful and most wonderful. PLoS Genetics, 19(4). doi:10.1371/journal.pgen.1010695 |
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Daneshnia, F., Hilmioglu-Polat, S., Ilkit, M., Fuentes, D., Lombardi, L., Binder, U., et al. (2023). Whole-genome sequencing confirms a persistent candidaemia clonal outbreak due to multidrug-resistant Candida parapsilosis. Journal of Antimicrobial Chemotherapy, 78(6), 1488-1494. doi:10.1093/jac/dkad112 |
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Daneshnia, F., Arastehfar, A., Lombardi, L., Binder, U., Scheler, J., Vahedi Shahandashti, R., et al. (2023). Candida parapsilosis isolates carrying mutations outside FKS1 hotspot regions confer high echinocandin tolerance and facilitate the development of echinocandin resistance. International Journal of Antimicrobial Agents, 62(1). doi:10.1016/j.ijantimicag.2023.106831 |
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Professor Annette Therese Byrne | |
Miller, I. S., Khan, S., Shiels, L. P., Das, S., O' Farrell, A. C., Connor, K., et al. (2022). Implementing subtype-specific pre-clinical models of breast cancer to study pre-treatment aspirin effects. Cancer Medicine, 11(20), 3820-3836. doi:10.1002/cam4.4756 |
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White, K., Connor, K., Meylan, M., Bougoüin, A., Salvucci, M., Bielle, F., et al. (2023). Identification, validation and biological characterisation of novel glioblastoma tumour microenvironment subtypes: implications for precision immunotherapy. Annals of Oncology, 34(3), 300-314. doi:10.1016/j.annonc.2022.11.008 |
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Caulfield, C., Wu, D., Miller, I. S., Byrne, A. T., Mac Aonghusa, P., Zhuk, S., et al. (2023). BF<inf>2</inf>-Azadipyrromethene Fluorophores for Intraoperative Vital Structure Identification. Molecules, 28(5). doi:10.3390/molecules28052167 |
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Virassamy, B., Caramia, F., Savas, P., Sant, S., Wang, J., Christo, S. N., et al. (2023). Intratumoral CD8<sup>+</sup> T cells with a tissue-resident memory phenotype mediate local immunity and immune checkpoint responses in breast cancer. Cancer Cell, 41(3), 585-601.e8. doi:10.1016/j.ccell.2023.01.004 |
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Biswas, A., Salvucci, M., Connor, K., Düssmann, H., Carberry, S., Fichtner, M., et al. (2023). Comparative analysis of deeply phenotyped GBM cohorts of ‘short-term’ and ‘long-term’ survivors. Journal of Neuro-Oncology, 163(2), 327-338. doi:10.1007/s11060-023-04341-3 |
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Li, R., Sant, S., Brown, E., Caramia, F., Nikolic, B., Clarke, K., et al. (2023). Tucatinib promotes immune activation and synergizes with programmed cell death-1 and programmed cell death-ligand 1 inhibition in HER2-positive breast cancer. Journal of the National Cancer Institute, 115(7), 805-814. doi:10.1093/jnci/djad072 |
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Assoc Professor Gerard Cagney | |
Zhang, W., Li, J., Silveira, C. P., Cai, Q., Dawson, K. A., Cagney, G., & Yan, Y. (2022). Nanoscale shape-dependent histone modifications.. PNAS nexus, 1(4), pgac172. doi:10.1093/pnasnexus/pgac172 |
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Davis, J. L., Kennedy, C., Clerkin, S., Treacy, N. J., Dodd, T., Moss, C., et al. (2022). Single-cell multiomics reveals the complexity of TGFß signalling to chromatin in iPSC-derived kidney organoids. Communications biology, 5(1), 1301. doi:10.1038/s42003-022-04264-1 |
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Susai, S. R., Healy, C., Mongan, D., Heurich, M., Byrne, J. F., Cannon, M., et al. (2022). Evidence that complement and coagulation proteins are mediating the clinical response to omega-3 fatty acids: A mass spectrometry-based investigation in subjects at clinical high-risk for psychosis. Translational Psychiatry, 12(1). doi:10.1038/s41398-022-02217-0 |
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Dr Hilary Cassidy | |
Liu, Z., Krstic, A., Neve, A., Casalou, C., Rauch, N., Wynne, K., et al. (2023). Kinase Suppressor of RAS 1 (KSR1) Maintains the Transformed Phenotype of BRAFV600E Mutant Human Melanoma Cells. International Journal of Molecular Sciences, 24(14). doi:10.3390/ijms241411821 |
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Ms Patrizia Colucci | |
Gómez Sánchez, A., Colucci, P., Moran, A., Moya López, A., Colligris, B., Álvarez, Y., & Kennedy, B. (2023). Systemic treatment with cigarette smoke extract affects zebrafish visual behaviour, intraocular vasculature morphology and outer segment phagocytosis. doi:10.12688/openreseurope.15491.1 |
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Colucci, P., Giannaccini, M., Baggiani, M., Kennedy, B. N., Dente, L., Raffa, V., & Gabellini, C. (2023). Neuroprotective Nanoparticles Targeting the Retina: A Polymeric Platform for Ocular Drug Delivery Applications. Pharmaceutics, 15(4). doi:10.3390/pharmaceutics15041096 |
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Dr Eric Conway | |
Healy, E., McCole, R., Monger, C., Nolan, J., Conway, E., Brien, G., et al. (2022). EZH1-PRC2 Identifies a Potential Reservoir for Disease Relapse in Quiescent Cancer Cells Refractory to EZH2 Enzymatic Inhibition. Blood, 140(Supplement 1), 3049-3050. doi:10.1182/blood-2022-168762 |
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Assoc Professor John Crean | |
McKiernan, E. P., Moloney, C., Chaudhuri, T. R., Clerkin, S., Behan, K., Straubinger, R. M., et al. (2022). Formation of hydrated PEG layers on magnetic iron oxide nanoflowers shows internal magnetisation dynamics and generates high in-vivo efficacy for MRI and magnetic hyperthermia. Acta Biomaterialia, 152, 393-405. doi:10.1016/j.actbio.2022.08.033 |
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Davis, J. L., Kennedy, C., Clerkin, S., Treacy, N. J., Dodd, T., Moss, C., et al. (2022). Single-cell multiomics reveals the complexity of TGFß signalling to chromatin in iPSC-derived kidney organoids. Communications biology, 5(1), 1301. doi:10.1038/s42003-022-04264-1 |
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Treacy, N. J., Clerkin, S., Davis, J. L., Kennedy, C., Miller, A. F., Saiani, A., et al. (2023). Growth and differentiation of human induced pluripotent stem cell (hiPSC)-derived kidney organoids using fully synthetic peptide hydrogels.. Bioactive materials, 21, 142-156. doi:10.1016/j.bioactmat.2022.08.003 |
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Dr Jessica Davis | |
Davis, J. L., Kennedy, C., Clerkin, S., Treacy, N. J., Dodd, T., Moss, C., et al. (2022). Single-cell multiomics reveals the complexity of TGFß signalling to chromatin in iPSC-derived kidney organoids. Communications biology, 5(1), 1301. doi:10.1038/s42003-022-04264-1 |
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Treacy, N. J., Clerkin, S., Davis, J. L., Kennedy, C., Miller, A. F., Saiani, A., et al. (2023). Growth and differentiation of human induced pluripotent stem cell (hiPSC)-derived kidney organoids using fully synthetic peptide hydrogels.. Bioactive materials, 21, 142-156. doi:10.1016/j.bioactmat.2022.08.003 |
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Dr Monica De Gaetano | |
de Gaetano, M. (2023). Development of synthetic lipoxin-A4 mimetics (sLXms): New avenues in the treatment of cardio-metabolic diseases. Seminars in Immunology, 65. doi:10.1016/j.smim.2022.101699 |
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Millar, B., & de Gaetano, M. (2023). Posing the rationale for synthetic lipoxin mimetics as an adjuvant treatment to gold standard atherosclerosis therapies. Frontiers in Pharmacology, 14. doi:10.3389/fphar.2023.1125858 |
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Dr Joanna Drabinska | |
O'Connor, A., Jurado-Martín, I., Mysior, M. M., Manzira, A. L., Drabinska, J., Simpson, J. C., et al. (2023). A universal stress protein upregulated by hypoxia has a role in Burkholderia cenocepacia intramacrophage survival: Implications for chronic infection in cystic fibrosis. MicrobiologyOpen, 12(1). doi:10.1002/mbo3.1311 |
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Professor William Gallagher | |
Mazo, C., Aura, C., Rahman, A., Gallagher, W. M., & Mooney, C. (2022). Application of Artificial Intelligence Techniques to Predict Risk of Recurrence of Breast Cancer: A Systematic Review. Journal of Personalized Medicine, 12(9). doi:10.3390/jpm12091496 |
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Krzyzanowska, A., Barron, S., Loughman, T., Higgins, D. F., Sheehan, K. M., Chan-Ju Wang, A., et al. (2022). 1411P Development and validation of a novel six-gene signature to accurately risk stratify men with early-stage prostate cancer to aid in treatment decision making. Annals of Oncology, 33, S1190. doi:10.1016/j.annonc.2022.07.1897 |
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Antoranz, A., Van Herck, Y., Bolognesi, M. M., Lynch, S. M., Rahman, A., Gallagher, W. M., et al. (2022). Mapping the Immune Landscape in Metastatic Melanoma Reveals Localized Cell–Cell Interactions That Predict Immunotherapy Response. Cancer Research, 82(18), 3275-3290. doi:10.1158/0008-5472.CAN-22-0363 |
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Miller, I. S., Khan, S., Shiels, L. P., Das, S., O' Farrell, A. C., Connor, K., et al. (2022). Implementing subtype-specific pre-clinical models of breast cancer to study pre-treatment aspirin effects. Cancer Medicine, 11(20), 3820-3836. doi:10.1002/cam4.4756 |
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Azam, H., Maher, S., Clarke, S., Carruthers, N., Marcone, S., Gallagher, W., & Prencipe, M. (2022). Serum response factor and androgen receptor; partners in crime in prostate cancer progression. European Urology Open Science, 44, S216. doi:10.1016/s2666-1683(22)01976-0 |
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Connor, K., Conroy, E., White, K., Shiels, L., Keek, S., Ibrahim, A., et al. (2022). MODL-24. ESTABLISHING A CLINICALLY RELEVANT CT AND ASSOCIATED RADIOMICS PIPELINE FOR INTRACRANIAL RODENT TUMOUR MODELS. Neuro-Oncology, 24(Supplement_7), vii295-vii296. doi:10.1093/neuonc/noac209.1151 |
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Wahlin, S., Boman, K., Moran, B., Nodin, B., Gallagher, W. M., Karnevi, E., & Jirström, K. (2022). Pre-clinical and clinical studies on the role of RBM3 in muscle-invasive bladder cancer: longitudinal expression, transcriptome-level effects and modulation of chemosensitivity. BMC Cancer, 22(1). doi:10.1186/s12885-021-09168-7 |
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Krzyzanowska, A., Barron, S., Higgins, D. F., Loughman, T., O'Neill, A., Sheehan, K. M., et al. (2023). Development, Validation, and Clinical Utility of a Six-gene Signature to Predict Aggressive Prostate Cancer. European Urology Focus. doi:10.1016/j.euf.2023.04.004 |
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Azam, H., Maher, S., Clarke, S., Gallagher, W. M., & Prencipe, M. (2023). SRF inhibitors reduce prostate cancer cell proliferation through cell cycle arrest in an isogenic model of castrate-resistant prostate cancer. Cell Cycle, 22(14-16), 1759-1776. doi:10.1080/15384101.2023.2229713 |
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Slater, K., Bosch, R., Smith, K. F., Jahangir, C. A., Garcia-Mulero, S., Rahman, A., et al. (2023). 1,4-dihydroxy quininib modulates the secretome of uveal melanoma tumour explants and a marker of oxidative phosphorylation in a metastatic xenograft model. Frontiers in Medicine, 9. doi:10.3389/fmed.2022.1036322 |
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Krzyzanowska, A., Barron, S., Higgins, D., Loughman, T., Sheehan, K., Chan-Ju Wang, A., et al. (2023). Development and clinical validation of a novel biopsy-based six-gene signature to accurately risk-stratify men with early-stage prostate cancer to aid treatment decision making.. Journal of Clinical Oncology, 41(6_suppl), 374. doi:10.1200/jco.2023.41.6_suppl.374 |
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Krzyzanowska, A., Barron, S., Higgins, D. F., Loughman, T., Sheehan, K. M., Chan-Ju Wang, A., et al. (2023). MP17-08 CLINICAL VALIDATION OF A NOVEL SIX-GENE RISK-STRATIFICATION SIGNATURE TO SUPPORT TREATMENT DECISIONS FOR MEN DIAGNOSED WITH PROSTATE CANCER. Journal of Urology, 209(Supplement 4). doi:10.1097/ju.0000000000003237.08 |
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Kinsella, Z., Blümel, A., Lucas, M., Lindner, A., Gonzalez, C. A., Rahman, A., et al. (2023). Abstract 5787: Modelling the spatial heterogeneity of CD45-positive tumor infiltrating lymphocytes in early-stage, estrogen receptor-positive breast cancer. Cancer Research, 83(7_Supplement), 5787. doi:10.1158/1538-7445.am2023-5787 |
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Lucas, M. W., Hurley, C., Kinsella, Z., Gonzalez, C., Burke, C., Rahman, A., et al. (2023). 78P Multiplex immunohistochemistry and digital pathology analysis examining the prevalence and prognostic value of tertiary lymphoid structures in early stage hormone positive, HER2-negative breast cancer. ESMO Open, 8(1), 101301. doi:10.1016/j.esmoop.2023.101301 |
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Lucas, M., Kinsella, Z., Gonzalez, C. A., Hurley, C., O'Grady, A., Fay, J., et al. (2023). The immune microenvironment in hormone positive, HER2 negative breast cancer: A focus on tumour infiltrating lymphocytes, spatial phenotypes and tertiary lymphoid structures.. Journal of Clinical Oncology, 41(16_suppl), 2522. doi:10.1200/jco.2023.41.16_suppl.2522 |
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Thagaard, J., Broeckx, G., Page, D. B., Jahangir, C. A., Verbandt, S., Kos, Z., et al. (2023). Pitfalls in machine learning-based assessment of tumor-infiltrating lymphocytes in breast cancer: a report of the international immuno-oncology biomarker working group. Journal of Pathology, 260(5), 498-513. doi:10.1002/path.6155 |
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Page, D. B., Broeckx, G., Jahangir, C. A., Verbandt, S., Gupta, R. R., Thagaard, J., et al. (2023). Spatial analyses of immune cell infiltration in cancer: current methods and future directions. A report of the International Immuno-Oncology Biomarker Working Group on Breast Cancer. Journal of Pathology, 260(5), 514-532. doi:10.1002/path.6165 |
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Ms Harsha Ganesan | |
Ganesan, H., Nandy, S. K., Banerjee, A., Pathak, S., Zhang, H., & Sun, X. F. (2022). RNA-Interference-Mediated miR-122-Based Gene Regulation in Colon Cancer, a Structural In Silico Analysis. International Journal of Molecular Sciences, 23(23). doi:10.3390/ijms232315257 |
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Dr Daniel Hawtree | |
Görgü, L., Hawtree, D., O'Grady, M. J., Muldoon, C., Masterson, B., Meijer, W. G., et al. (2023). The MÉRA Data Extraction toolkit. Meteorological Applications, 30(1). doi:10.1002/met.2111 |
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Assoc Professor Caroline Herron | |
Li, Y., Zhang, F., Herron, C. E., Rosales, I., Heredia, A., Buchete, N. -V., & Rodriguez, B. J. (2023). Cannabidiol-Mediated Sequestration of Alzheimer’s Amyloid-&lt;i&gt;ß&lt;/i&gt; Peptides in ADDL Oligomers. American Journal of Molecular Biology, 13(02), 113-126. doi:10.4236/ajmb.2023.132008 |
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Dr David Hughes | |
Demircan, K., Chillon, T. S., Bracken, T., Bulgarelli, I., Campi, I., Du Laing, G., et al. (2022). Association of COVID-19 mortality with serum selenium, zinc and copper: Six observational studies across Europe. Frontiers in Immunology, 13. doi:10.3389/fimmu.2022.1022673 |
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Karavasiloglou, N., Hughes, D. J., Murphy, N., Schomburg, L., Sun, Q., Seher, V., et al. (2023). Prediagnostic serum calcium concentrations and risk of colorectal cancer development in 2 large European prospective cohorts. American Journal of Clinical Nutrition, 117(1), 33-45. doi:10.1016/j.ajcnut.2022.10.004 |
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Aglago, E. K., Cross, A. J., Riboli, E., Fedirko, V., Hughes, D. J., Fournier, A., et al. (2023). Dietary intake of total, heme and non-heme iron and the risk of colorectal cancer in a European prospective cohort study. British Journal of Cancer, 128(8), 1529-1540. doi:10.1038/s41416-023-02164-7 |
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Daniel, N., Genua, F., Jenab, M., Mayén, A. -L., Chrysovalantou Chatziioannou, A., Keski-Rahkonen, P., & Hughes, D. J. (2023). The role of the gut microbiome in the development of hepatobiliary cancers.. Hepatology (Baltimore, Md.). doi:10.1097/hep.0000000000000406 |
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Genua, F., Butt, J., Waterboer, T., & Hughes, D. J. (2023). Association of Antibody Responses to Fusobacterium nucleatum and Streptococcus gallolyticus Proteins with Colorectal Adenoma and Colorectal Cancer. Digestive Diseases and Sciences, 68(8), 3300-3311. doi:10.1007/s10620-023-08001-4 |
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Professor Breandán Kennedy | |
Moran, A. L., Fehilly, J. D., Floss Jones, D., Collery, R., & Kennedy, B. N. (2022). Regulation of the rhythmic diversity of daily photoreceptor outer segment phagocytosis in vivo. FASEB Journal, 36(10). doi:10.1096/fj.202200990RR |
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Smith, A. J., Advani, J., Brock, D. C., Nellissery, J., Gumerson, J., Dong, L., et al. (2022). GATD3A, a mitochondrial deglycase with evolutionary origins from gammaproteobacteria, restricts the formation of advanced glycation end products. BMC Biology, 20(1). doi:10.1186/s12915-022-01267-6 |
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Gómez Sánchez, A., Colucci, P., Moran, A., Moya López, A., Colligris, B., Álvarez, Y., & Kennedy, B. (2023). Systemic treatment with cigarette smoke extract affects zebrafish visual behaviour, intraocular vasculature morphology and outer segment phagocytosis. doi:10.12688/openreseurope.15491.1
Sundaramurthi, H., Tonelotto, V., Wynne, K., O'Connell, F., O’Reilly, E., Costa-Garcia, M., et al. (2023). Ergolide mediates anti-cancer effects on metastatic uveal melanoma cells and modulates their cellular and extracellular vesicle proteomes. doi:10.12688/openreseurope.15973.1
Slater, K., Bosch, R., Smith, K. F., Jahangir, C. A., Garcia-Mulero, S., Rahman, A., et al. (2023). 1,4-dihydroxy quininib modulates the secretome of uveal melanoma tumour explants and a marker of oxidative phosphorylation in a metastatic xenograft model. Frontiers in Medicine, 9. doi:10.3389/fmed.2022.1036322
Colucci, P., Giannaccini, M., Baggiani, M., Kennedy, B. N., Dente, L., Raffa, V., & Gabellini, C. (2023). Neuroprotective Nanoparticles Targeting the Retina: A Polymeric Platform for Ocular Drug Delivery Applications. Pharmaceutics, 15(4). doi:10.3390/pharmaceutics15041096
Dhami, S. P. S., Patmore, S., Comerford, C., Byrne, C., Cavanagh, B., Castle, J., et al. (2022). Breast cancer cells mediate endothelial cell activation, promoting von Willebrand factor release, tumor adhesion, and transendothelial migration. Journal of Thrombosis and Haemostasis, 20(10), 2350-2365. doi:10.1111/jth.15794
Khan, M. F., & Murphy, C. D. (2022). Cytochrome P450 5208A3 is a promiscuous xenobiotic biotransforming enzyme in Cunninghamella elegans. Enzyme and Microbial Technology, 161. doi:10.1016/j.enzmictec.2022.110102
Dobson, L. S., Zhang, Q., McKay, B. A., Oke, O., Isanbor, C., Khan, M. F., et al. (2023). Aryl (ß,ß',ß"-Trifluoro)-tert-butyl: A Candidate Motif for the Discovery of Bioactives. Organic Letters. doi:10.1021/acs.orglett.3c02236
Khan, M. F., & Murphy, C. D. (2023). Fluorotelomer alcohols are efficiently biotransformed by Cunninghamella elegans. Environmental Science and Pollution Research, 30(9), 23613-23623. doi:10.1007/s11356-022-23901-0
Khan, M. F., Chowdhary, S., Koksch, B., & Murphy, C. D. (2023). Biodegradation of Amphipathic Fluorinated Peptides Reveals a New Bacterial Defluorinating Activity and a New Source of Natural Organofluorine Compounds. Environmental Science and Technology, 57(26), 9762-9772. doi:10.1021/acs.est.3c01240
Khan, M. F., Paul Guin, J., Thampi, R. K., Sullivan, J. A., & Murphy, C. D. (2023). Enhanced removal of perfluorooctanoic acid with sequential photocatalysis and fungal treatment. Environmental Science and Pollution Research, 30(39), 91478-91486. doi:10.1007/s11356-023-28588-5
Lombardi, L., Bergin, S. A., Ryan, A., Zuniga-Soto, E., & Butler, G. (2022). CRISPR-Cas9 Editing Induces Loss of Heterozygosity in the Pathogenic Yeast Candida parapsilosis. mSphere, 7(6). doi:10.1128/msphere.00393-22
Salzberg, L. I., Martos, A. A. R., Lombardi, L., Jermiin, L. S., Blanco, A., Byrne, K. P., & Wolfe, K. H. (2022). A widespread inversion polymorphism conserved among Saccharomyces species is caused by recurrent homogenization of a sporulation gene family. PLoS Genetics, 18(11). doi:10.1371/journal.pgen.1010525
Daneshnia, F., Arastehfar, A., Lombardi, L., Binder, U., Scheler, J., Vahedi Shahandashti, R., et al. (2023). Candida parapsilosis isolates carrying mutations outside FKS1 hotspot regions confer high echinocandin tolerance and facilitate the development of echinocandin resistance. International Journal of Antimicrobial Agents, 62(1). doi:10.1016/j.ijantimicag.2023.106831
Rohlfing, A. K., Kolb, K., Sigle, M., Ziegler, M., Bild, A., Münzer, P., et al. (2022). ACKR3 regulates platelet activation and ischemia-reperfusion tissue injury. Nature Communications, 13(1). doi:10.1038/s41467-022-29341-1
Contursi, A., Fullone, R., Szklanna-Koszalinska, P., Marcone, S., Lanuti, P., Taus, F., et al. (2023). Tumor-Educated Platelet Extracellular Vesicles: Proteomic Profiling and Crosstalk with Colorectal Cancer Cells. Cancers, 15(2). doi:10.3390/cancers15020350
O’Reilly, D., Murphy, C. A., Moore, C. M., Ní Áinle, F., Gormley, I. C., Morrell, C. N., et al. (2023). Markers of platelet activation foR identification of late onset sEpsis in infaNTs: PARENT study protocol. Pediatric Research. doi:10.1038/s41390-023-02812-x
Weiss, L., MacLeod, H., Comer, S. P., Cullivan, S., Szklanna, P. B., Ní Áinle, F., et al. (2023). An optimized protocol to isolate quiescent washed platelets from human whole blood and generate platelet releasate under clinical conditions. STAR Protocols, 4(2). doi:10.1016/j.xpro.2023.102150
Manresa, M. C., Miki, H., Miller, J., Okamoto, K., Dobaczewska, K., Herro, R., et al. (2022). A Deficiency in the Cytokine TNFSF14/LIGHT Limits Inflammation and Remodeling in Murine Eosinophilic Esophagitis. Journal of Immunology, 209(12), 2341-2351. doi:10.4049/jimmunol.2200326
Miki, H., Kiosses, W. B., Manresa, M. C., Gupta, R. K., Sethi, G. S., Herro, R., et al. (2023). Lymphotoxin beta receptor signaling directly controls airway smooth muscle deregulation and asthmatic lung dysfunction. Journal of Allergy and Clinical Immunology, 151(4), 976-990.e5. doi:10.1016/j.jaci.2022.11.016
Miki, H., & Manresa, M. C. (2023). Novel fibroblast phenotypes in homeostasis and chronic inflammation: From functions to potential regulators. Journal of Physiology, 601(12), 2273-2291. doi:10.1113/JP284620
Assoc Professor Siobhán McClean
Quinn, C., Tomás-Cortázar, J., Ofioritse, O., Cosgrave, J., Purcell, C., McAloon, C., et al. (2023). GlnH, a Novel Antigen That Offers Partial Protection against Verocytotoxigenic Escherichia coli Infection. Vaccines, 11(1). doi:10.3390/vaccines11010175
O'Connor, A., Jurado-Martín, I., Mysior, M. M., Manzira, A. L., Drabinska, J., Simpson, J. C., et al. (2023). A universal stress protein upregulated by hypoxia has a role in Burkholderia cenocepacia intramacrophage survival: Implications for chronic infection in cystic fibrosis. MicrobiologyOpen, 12(1). doi:10.1002/mbo3.1311
Dunne, K., Reece, E., McClean, S., Doyle, S., Rogers, T. R., Murphy, P., & Renwick, J. (2023). Aspergillus fumigatus Supernatants Disrupt Bronchial Epithelial Monolayers: Potential Role for Enhanced Invasion in Cystic Fibrosis. Journal of Fungi, 9(4). doi:10.3390/jof9040490
Roszkowiak, J., McClean, S., Mironczuk, A. M., & Augustyniak, D. (2023). The Direct Anti-Virulence but Not Bactericidal Activity of Human Neutrophil Elastase against Moraxella catarrhalis. International Journal of Molecular Sciences, 24(7). doi:10.3390/ijms24076607
Karah, N., Mateo-Estrada, V., Castillo-Ramírez, S., Higgins, P. G., Havenga, B., Khan, W., et al. (2023). The <i>Acinetobacter baumannii</i> website (Ab-web): a multidisciplinary knowledge hub, communication platform, and workspace.. FEMS microbes, 4, xtad009. doi:10.1093/femsmc/xtad009
Assoc Professor Margaret McGee
Kulka, M., Brennan, K., & Gee, M. M. (2022). Investigation of canine extracellular vesicles in diffuse large B-cell lymphomas. PLoS ONE, 17(9 September). doi:10.1371/journal.pone.0274261
Brennan, K., Iversen, K. F., Blanco-Fernández, A., Lund, T., Plesner, T., & Mc Gee, M. M. (2022). Extracellular Vesicles Isolated from Plasma of Multiple Myeloma Patients Treated with Daratumumab Express CD38, PD-L1, and the Complement Inhibitory Proteins CD55 and CD59. Cells, 11(21). doi:10.3390/cells11213365
Gorry, R., Brennan, K., Lavin, P. T. M., Sheridan, R., & Mc Gee, M. M. (2023). Phosphorylation of the prolyl isomerase Cyclophilin A regulates its localisation and release from the centrosome during mitosis. Cell Cycle, 22(8), 951-966. doi:10.1080/15384101.2023.2167430
Gorry, R. L., Brennan, K., Lavin, P. T. M., Mazurski, T., Mary, C., Matallanas, D., et al. (2023). Cyclophilin A Isomerisation of Septin 2 Mediates Abscission during Cytokinesis. International Journal of Molecular Sciences, 24(13). doi:10.3390/ijms241311084
Obaidi, I., Blanco Fernández, A., & McMorrow, T. (2022). Curcumin Sensitises Cancerous Kidney Cells to TRAIL Induced Apoptosis via Let-7C Mediated Deregulation of Cell Cycle Proteins and Cellular Metabolism. International Journal of Molecular Sciences, 23(17). doi:10.3390/ijms23179569
Ibáñez Gaspar, V., & McMorrow, T. (2023). The Curcuminoid EF24 in Combination with TRAIL Reduces Human Renal Cancer Cell Migration by Decreasing MMP-2/MMP-9 Activity through a Reduction in H<inf>2</inf>O<inf>2</inf>. International Journal of Molecular Sciences, 24(2). doi:10.3390/ijms24021043
Reynolds, L. J., Gonzalez, G., Sala-Comorera, L., Martin, N. A., Byrne, A., Fennema, S., et al. (2022). SARS-CoV-2 variant trends in Ireland: Wastewater-based epidemiology and clinical surveillance. Science of the Total Environment, 838. doi:10.1016/j.scitotenv.2022.155828
Mahon, J. M., Monleon, A. J. C., Gill, L. W., O’Sullivan, J. J., & Meijer, W. G. (2022). Wastewater-based epidemiology (WBE) for SARS-CoV-2 – A review focussing on the significance of the sewer network using a Dublin city catchment case study. Water Science and Technology, 86(6), 1402-1425. doi:10.2166/wst.2022.278
Steenbeek, R., Emke, E., Vughs, D., Matias, J., Boogaerts, T., Castiglioni, S., et al. (2022). Spatial and temporal assessment of crack cocaine use in 13 European cities through wastewater-based epidemiology. Science of the Total Environment, 847. doi:10.1016/j.scitotenv.2022.157222
Görgü, L., Hawtree, D., O'Grady, M. J., Muldoon, C., Masterson, B., Meijer, W. G., et al. (2023). The MÉRA Data Extraction toolkit. Meteorological Applications, 30(1). doi:10.1002/met.2111
Cogliati, M., Arikan-Akdagli, S., Barac, A., Bostanaru, A. C., Brito, S., Çerikçioglu, N., et al. (2023). Environmental and bioclimatic factors influencing yeasts and molds distribution along European shores. Science of the Total Environment, 859. doi:10.1016/j.scitotenv.2022.160132
Martin, N. A., Gonzalez, G., Reynolds, L. J., Bennett, C., Campbell, C., Nolan, T. M., et al. (2023). Adeno-Associated Virus 2 and Human Adenovirus F41 in Wastewater during Outbreak of Severe Acute Hepatitis in Children, Ireland. Emerging Infectious Diseases, 29(4), 751-760. doi:10.3201/eid2904.221878
Nolan, T. M., Reynolds, L. J., Sala-Comorera, L., Martin, N. A., Stephens, J. H., O'Hare, G. M. P., et al. (2023). Land use as a critical determinant of faecal and antimicrobial resistance gene pollution in riverine systems. Science of the Total Environment, 871. doi:10.1016/j.scitotenv.2023.162052
Gao, G., O’Sullivan, J. J., Corkery, A., Bedri, Z., O’Hare, G. M. P., & Meijer, W. G. (2023). The Use of Transport Time Scales as Indicators of Pollution Persistence in a Macro-Tidal Setting. Journal of Marine Science and Engineering, 11(5), 1073. doi:10.3390/jmse11051073
Martin, N. A., Sala-Comorera, L., Gao, G., Corkery, A., Reynolds, L. J., Nolan, T. M., et al. (2023). Inclusion of hydrodynamic properties of bathing waters is critical in selecting faecal indicators to assess public health impacts of faecal contamination. Water Research, 242. doi:10.1016/j.watres.2023.120137
Sweeney, J. B., McDonnell, K., & Murphy, C. D. (2022). Improving the specificity of E. coli acetate/propionate exclusion biosensors via iterative engineering. Enzyme and Microbial Technology, 160. doi:10.1016/j.enzmictec.2022.110091
Khan, M. F., & Murphy, C. D. (2022). Cytochrome P450 5208A3 is a promiscuous xenobiotic biotransforming enzyme in Cunninghamella elegans. Enzyme and Microbial Technology, 161. doi:10.1016/j.enzmictec.2022.110102
Dobson, L. S., Zhang, Q., McKay, B. A., Oke, O., Isanbor, C., Khan, M. F., et al. (2023). Aryl (ß,ß',ß"-Trifluoro)-tert-butyl: A Candidate Motif for the Discovery of Bioactives. Organic Letters. doi:10.1021/acs.orglett.3c02236
Bhatt, P., Chen, S., & Murphy, C. (2023). Editorial: Recent advancements in microbe-pesticide interaction: a smart-soil bioremediation approach. Frontiers in Microbiology, 14. doi:10.3389/fmicb.2023.1206179
Khan, M. F., & Murphy, C. D. (2023). Fluorotelomer alcohols are efficiently biotransformed by Cunninghamella elegans. Environmental Science and Pollution Research, 30(9), 23613-23623. doi:10.1007/s11356-022-23901-0
Khan, M. F., Chowdhary, S., Koksch, B., & Murphy, C. D. (2023). Biodegradation of Amphipathic Fluorinated Peptides Reveals a New Bacterial Defluorinating Activity and a New Source of Natural Organofluorine Compounds. Environmental Science and Technology, 57(26), 9762-9772. doi:10.1021/acs.est.3c01240
Khan, M. F., Paul Guin, J., Thampi, R. K., Sullivan, J. A., & Murphy, C. D. (2023). Enhanced removal of perfluorooctanoic acid with sequential photocatalysis and fungal treatment. Environmental Science and Pollution Research, 30(39), 91478-91486. doi:10.1007/s11356-023-28588-5
Holtby, A. R., McGivney, B. A., Browne, J. A., Katz, L. M., Murphy, K. J., & Hill, E. W. (2023). Variation in salivary cortisol responses in yearling Thoroughbred racehorses during their first year of training. PLoS ONE, 18(4 April). doi:10.1371/journal.pone.0284102
Holtby, A. R., Hall, T. J., McGivney, B. A., Han, H., Murphy, K. J., MacHugh, D. E., et al. (2023). Integrative genomics analysis highlights functionally relevant genes for equine behaviour. Animal Genetics, 54(4), 457-469. doi:10.1111/age.13320
Liu, S., Narancic, T., Tham, J. L., & O’Connor, K. E. (2023). ß-oxidation–polyhydroxyalkanoates synthesis relationship in Pseudomonas putida KT2440 revisited. Applied Microbiology and Biotechnology, 107(5-6), 1863-1874. doi:10.1007/s00253-023-12413-7
Wang, S., Malebari, A. M., Greene, T. F., Kandwal, S., Fayne, D., Nathwani, S. M., et al. (2023). Antiproliferative and Tubulin-Destabilising Effects of 3-(Prop-1-en-2-yl)azetidin-2-Ones and Related Compounds in MCF-7 and MDA-MB-231 Breast Cancer Cells.. Pharmaceuticals (Basel, Switzerland), 16(7), 1000. doi:10.3390/ph16071000
Assoc Professor David O'Connell
Ward, S. E., Guest, T., Byrne, C., Lopes, P., O'Sullivan, J. M., Doherty, D., et al. (2023). Macrophage Galactose Lectin Contributes to the Regulation of FVIII (Factor VIII) Clearance in Mice - Brief Report. Arteriosclerosis, Thrombosis, and Vascular Biology, 43(4), 540-546. doi:10.1161/ATVBAHA.122.317807
Moreton, N., Puzio, M., & O'Connor, J. J. (2022). The effects of the superoxide dismutase mimetic, MnTMPyP, post hypoxia and oxygen glucose deprivation in isolated rat hippocampal slices. Brain Research Bulletin, 190, 105-115. doi:10.1016/j.brainresbull.2022.09.021
Puzio, M., Moreton, N., Sullivan, M., Scaife, C., Glennon, J. C., & O’Connor, J. J. (2023). An Electrophysiological and Proteomic Analysis of the Effects of the Superoxide Dismutase Mimetic, MnTMPyP, on Synaptic Signalling Post-Ischemia in Isolated Rat Hippocampal Slices. Antioxidants, 12(4). doi:10.3390/antiox12040792
Offei, B., Braun-Galleani, S., Venkatesh, A., Casey, W. T., O'Connor, K. E., Byrne, K. P., & Wolfe, K. H. (2022). Identification of genetic variants of the industrial yeast Komagataella phaffii (Pichia pastoris) that contribute to increased yields of secreted heterologous proteins. PLoS Biology, 20(12). doi:10.1371/journal.pbio.3001877
Liu, S., Narancic, T., Tham, J. L., & O’Connor, K. E. (2023). ß-oxidation–polyhydroxyalkanoates synthesis relationship in Pseudomonas putida KT2440 revisited. Applied Microbiology and Biotechnology, 107(5-6), 1863-1874. doi:10.1007/s00253-023-12413-7
Gaffey, J., O’Donovan, C., Murphy, D., O’Connor, T., Walsh, D., Vergara, L. A., et al. (2023). Synergetic Benefits for a Pig Farm and Local Bioeconomy Development from Extended Green Biorefinery Value Chains. Sustainability (Switzerland), 15(11). doi:10.3390/su15118692
Assoc Professor Tadhg Ó'Cróinín
Carney, G., Weimer, B. C., Clyne, M., & Cróinín, T. (2023). Different stages of the infection cycle are enriched for Campylobacter strains with distinct phenotypes and levels of fluoroquinolone resistance. Microbiology (United Kingdom), 169(6). doi:10.1099/mic.0.001349
Assoc Professor Niamh O'Sullivan
Byrne, D. J., Garcia-Pardo, M. E., Cole, N. B., Batnasan, B., Heneghan, S., Sohail, A., et al. (2022). Liver X receptor-agonist treatment rescues degeneration in a Drosophila model of hereditary spastic paraplegia. Acta Neuropathologica Communications, 10(1). doi:10.1186/s40478-022-01343-6
O'Sullivan, N. (2023). The nilpotent genus of finitely generated residually nilpotent groups. Journal of Group Theory. doi:10.1515/jgth-2022-0098
Azam, H., Maher, S., Clarke, S., Carruthers, N., Marcone, S., Gallagher, W., & Prencipe, M. (2022). Serum response factor and androgen receptor; partners in crime in prostate cancer progression. European Urology Open Science, 44, S216. doi:10.1016/s2666-1683(22)01976-0
Azam, H., Maher, S., Clarke, S., Gallagher, W. M., & Prencipe, M. (2023). SRF inhibitors reduce prostate cancer cell proliferation through cell cycle arrest in an isogenic model of castrate-resistant prostate cancer. Cell Cycle, 22(14-16), 1759-1776. doi:10.1080/15384101.2023.2229713
Liu, Z., Krstic, A., Neve, A., Casalou, C., Rauch, N., Wynne, K., et al. (2023). Kinase Suppressor of RAS 1 (KSR1) Maintains the Transformed Phenotype of BRAFV600E Mutant Human Melanoma Cells. International Journal of Molecular Sciences, 24(14). doi:10.3390/ijms241411821
Imoto, H., Rauch, N., Neve, A. J., Khorsand, F., Kreileder, M., Alexopoulos, L. G., et al. (2023). A Combination of Conformation-Specific RAF Inhibitors Overcome Drug Resistance Brought about by RAF Overexpression. Biomolecules, 13(8). doi:10.3390/biom13081212
Reynaud, E. (2022). The Blaschka legacy, illuminating the oceans from the heart of Europe. FMR magazine (Franco Maria Ricci Magazine).
Trentelman, J. J. A., de Vogel, F. A., Colstrup, E., Sima, R., Coumou, J., Koetsveld, J., et al. (2022). Identification of novel conserved Ixodes vaccine candidates; a promising role for non-secreted salivary gland proteins. Vaccine, 40(52), 7593-7603. doi:10.1016/j.vaccine.2022.10.032
Quinn, C., Tomás-Cortázar, J., Ofioritse, O., Cosgrave, J., Purcell, C., McAloon, C., et al. (2023). GlnH, a Novel Antigen That Offers Partial Protection against Verocytotoxigenic Escherichia coli Infection. Vaccines, 11(1). doi:10.3390/vaccines11010175
Rana, V. S., Kitsou, C., Dutta, S., Ronzetti, M. H., Zhang, M., Bernard, Q., et al. (2023). Dome1-JAK-STAT signaling between parasite and host integrates vector immunity and development.. Science (New York, N.Y.), 379(6628), eabl3837. doi:10.1126/science.abl3837
Weiss, L., MacLeod, H., Comer, S. P., Cullivan, S., Szklanna, P. B., Ní Áinle, F., et al. (2023). An optimized protocol to isolate quiescent washed platelets from human whole blood and generate platelet releasate under clinical conditions. STAR Protocols, 4(2). doi:10.1016/j.xpro.2023.102150
Assoc Professor Margaret Worrall
Singh, S., O’Reilly, S., Gewaid, H., Bowie, A. G., Gautier, V., & Worrall, D. M. (2022). Reactive Centre Loop Mutagenesis of SerpinB3 to Target TMPRSS2 and Furin: Inhibition of SARS-CoV-2 Cell Entry and Replication. International Journal of Molecular Sciences, 23(20). doi:10.3390/ijms232012522
Zhang, W., Li, J., Silveira, C. P., Cai, Q., Dawson, K. A., Cagney, G., & Yan, Y. (2022). Nanoscale shape-dependent histone modifications.. PNAS nexus, 1(4), pgac172. doi:10.1093/pnasnexus/pgac172
Wang, Y. F., Zhou, Y., Sun, J. B., Wang, X., Jia, Y., Ge, K., et al. (2023). The Yin and Yang of the protein corona on the delivery journey of nanoparticles. Nano Research, 16(1), 715-734. doi:10.1007/s12274-022-4849-6
Behan, J. A., Xie, Z., Wang, Y. F., Yang, X., Aastrup, T., Yan, Y., et al. (2023). Quartz Crystal Microbalance Method to Measure Nanoparticle-Receptor Interactions and Evaluate Nanoparticle Design Efficiency. JACS Au, 3(6), 1623-1633. doi:10.1021/jacsau.3c00084
Dr Daniel Hawtree | |
Zurovec, O., Hawtree, D., Leach, S., & Lynch, B. (2023). Impact of agricultural land use and management on available soil phosphorus content in agricultural catchments of Ireland. doi:10.5194/egusphere-egu23-17071 |
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Mellander, P. -E., Hawtree, D., Ezzati, G., Murphy, C., Galloway, J., Jackson-Blake, L., et al. (2023). Land to water phosphorus transfer processes under climate change. doi:10.5194/egusphere-egu23-6014 |
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Hawtree, D., Galloway, J., Zurovec, O., Jackson-Blake, L., Norling, M., & Mellander, P. -E. (2023). Performance of a Parsimonious Phosphorus Model (SimplyP) in Two Contrasting Agricultural Catchments in Ireland. doi:10.5194/egusphere-egu23-7759 |
Dr Jana Haase | |
Jones, A. K. C., Spreng, S. A., Brown, E., Mc Veigh, C. J., Inoue, A., Ahnert-Hilger, G., & Haase, J. (2023). Serotonin transporter regulation by Ga proteins: evidence for coupling of serotonin transport and the G protein cycle. Poster session presented at the meeting of 20th Meeting of the International Society for Serotonin Research "Serotonin on the Mexican Caribbean”. |
Professor Oliver Blacque | |
Pir, M., Yenisert, F., Karaman, A., Begar, E., Tsiropoulou, S., Firat-Karalar, E. N., et al. (2023). CilioGenics: an integrated method and database for predicting novel ciliary genes. doi:10.1101/2023.03.31.535034 |
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Dr Eric Conway | |
Deevy, O., Monger, C., Matrà, F., Tuck, E., Conway, E., Rodighiero, S., et al. (2023). Dominant negative and directional dysregulation of Polycomb function in<i>EZH2</i>-mutant human growth disorders. doi:10.1101/2023.06.01.543208 |
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Dr Emmanuel Reynaud | |
Andrea, S., Kevin, M., Brian J, R., & Emmanuel G, R. (2023). The Use of Fluid-phase 3D Printing to Pattern Alginate-gelatin Hydrogel Properties to Guide Cell Growth and Behaviour<i>In Vitro</i>. doi:10.1101/2023.07.08.547691 |
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Reynaud, E., Gutierrez-Heredia, L., Garbett, A., Horn, E., Carlsson, J., & Collins, P. (2023). Rise of the Cybercrabs: how digital cloning in an integrated taxonomic framework can support deep-sea exploration. doi:10.1101/2023.03.16.532964 |