New Therapeutics

As pioneers in predictive modelling, precision medicine and bio-clinical informatics, UCD experts are pushing frontiers in translational research and the development of new therapeutics. Our researchers are bringing the lived experience of patients to the fore, in order to improve the quality of research and its relevance to society, and to positively impact patient outcomes.

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Research Units and Programmes

NIBRT: Ireland's world-class bioprocessing facility

Established in 2011 by UCD in partnership with TCD, DCU and Sligo IT, NIBRT is a global leader in the development of innovative technologies to advance biopharmaceutical manufacturing. This innovative collaboration between Industry, Government and Academia is an invaluable resource for the global biopharmaceutical industry, making transformative discoveries across multidisciplinary areas for the manufacturing of accessible and affordable medicines.

Featured Researchers

New research reveals power of nanoinformatics

In a major collaborative work, an international team including UCD's Professor Vladimir Lobaskin, has discovered a new response mechanism specific to exposure to nanoparticles that is common to multiple species. By analysing a large collection of datasets, they have revealed an ancestral epigenetic mechanism of defence that explains how different species, from humans to simpler creatures, adapt to this type of exposure. Their paper published in Nature Nanotechnology is the first demonstration of the power of nanoinformatics, a new field of research extending the ideas from cheminformatics and bioinformatics.

Using digital models to transform child cancer treatment

  • Seán Duke, The Irish Times

A consortium of five Irish universities, six Irish charities and seven industrial partners with funding from SFI and industry, Precision Oncology Ireland is coordinated by Systems Biology Ireland. A core project is using samples from patients with neuroblastoma, a cancer affecting children aged five and under, to develop digital twin treatment models. These twins help doctors to better monitor individual patients, and devise optimal treatments which reduce patient exposure to toxins to the absolute minimum that is needed, and reduce severe side effects for children with cancer. 

 

August 2015

The dynamic control of signal transduction networks in cancer cells

Nature Reviews

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July 2021

Pro-resolving lipid mediators: regulators of inflammation, metabolism and kidney function

Nature Reviews Nephrology

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September 2017

Clustal Omega for making accurate alignments of many protein sequences

Protein Science

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July 2015

A randomized, controlled trial of 3.0 mg of liraglutide in weight management

New England Journal of Medicine

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