Current Openings

Systems Biology Ireland (SBI) / University College Dublin (UCD) is looking for a Research Scientist to work on the development of a novel class of signal transduction inhibitors. SBI is amongst the worldwide leading systems biology research institutes with a focus on understanding cancer and designing new therapies for cancer.

This position is part of a Research Ireland funded project, which aims to validate a new generation of inhibitors specifically targeting scaffolding proteins in the RAS-RAF-MEK-ERK pathway. This pathway drives >60% of all human cancers. Despite the availability of inhibitors against all components, there is still an urgent need for inhibitors that have higher response rates, are less toxic, and avoid the development of resistance.

The successful candidate will be responsible for conducting cell biology and molecular biology experiments as part of a collaborative team. A strong background in biochemistry and molecular biology is essential. Proficiency in techniques such as cell culture, cell transfection, viability assays, Western blotting, co-immunoprecipitation, and kinase assays is required. Experience in cancer biology, signal transduction, or drug development are an advantage. The ideal candidate will have a third level degree, be self-driven, collaborative, and comfortable working across disciplinary boundaries. The post is initially available for 8 months.

If interested, contact:
Prof. Walter Kolch
(opens in a new window)walter.kolch@ucd.ie