Biofilm Engineering
Research Group
Biofilms are formed when microorganisms form a community
at a solid-liquid interface. The complexity of biofilm metabolic behaviour
has simultaneously
limited our ability to fully exploit engineered biofilms as versatile
biocatalysts as well as limiting our complete understanding of why
unwanted biofilms are particularly resistant to antimicrobial agents.
Our approach involves a combination of experimental investigations
with mathematical modelling. We are
particularly interested in the
interactions between the physico-chemical microenvironment and microbial
physiology. Our group is interdisciplinary and we are engaged in
collaborative projects both nationally and internationally.
On-going research projects include:
(1) Investigation of the factors that determine physiological heterogeneity
in bacterial biofilms
(2) Development of a novel drug delivery system for biofilm associated
infections
(3) Scale-up of the membrane aerated biofilm reactor